DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17684 and CG11034

DIOPT Version :9

Sequence 1:	NP_001015352.3	Gene:	CG17684 / 3355066	FlyBaseID:	FBgn0263780	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001285638.1	Gene:	CG11034 / 33810	FlyBaseID:	FBgn0031741	Length:	751	Species:	Drosophila melanogaster

Alignment Length:	790	Identity:	227/790 - (28%)
Similarity:	367/790 - (46%)	Gaps:	81/790 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 TAIYLLGYVD----ELLYWSGRRMILDEYLQGDLIPRRLPSSWVTTQKYVFQSDDGSLAVLDTTT 124
            ||..::|.||    ....|.     |.|.|.|....|....:|:|...|.  :.|.|:...:..|
  Fly    23 TAAAVIGRVDGAEGNKTAWE-----LTEALYGTSGLRSFNGTWITGTYYT--ATDRSIHKFNAAT 80

  Fly   125 NLVKVLVTNHTLRQLNVRRYLCSSDLKYVLFTHNVKKNFQKSFTAFYTIYDV-TNDHHTPVKLKD 188
            ....:...:..|.......:..|.|...:|..||:.:.|:.|:.|.|.::|: ||         .
  Fly    81 KTDVIFQNSSFLNNYVGATFSLSPDNTKILIRHNLTEKFRHSYIAQYDVFDIETN---------T 136

  Fly   189 TLKVQR-TRLQYASWLGNTTAIIFVVKNDIFIRQSPLVEEDIRITSSGHENHIYNGVPDWLYQEE 252
            |:::.: .:|||..|......:.:|..|::||..|..:|  |.||..|.:..:|||||||:|:||
  Fly   137 TVQIHKGEKLQYCGWSPLRDRLAYVYLNNVFIHFSESLE--ISITDDGVDGVVYNGVPDWVYEEE 199

  Fly   253 IFETPEAIWTSSDGTHFMYALFNDTNVGMMTYPWLSSGALFSGSGIFSGSIFPETKMVRFPTPGT 317
            :..:..|||.||||:......||||.|...||       ...|.|..:...:|..:.:::|..|:
  Fly   200 VLSSGSAIWWSSDGSRLAVGFFNDTEVETFTY-------FLYGDGATTFYQYPHEEQLKYPKSGS 257

  Fly   318 TNPEVELWAVDITNLSDIQKFNIKPPATIYGQDYYLTSAGWISDSNCQVSVVYMGRSQNYSVISL 382
            .||.|.|...|::: :|.....|..|..|.|.|:.|.|..|  .::..:.:.:|.|.||.:.|..
  Fly   258 KNPVVSLRVYDVSD-NDPTMHTIVAPVDIVGDDHILQSVVW--SNSTHLLITWMNRRQNLTSIQS 319

  Fly   383 CSKEEDWKCLEVHSERAPEDEWLDIFPHPVFSSDGSSFLFLANIQESENYQFTHIKHVMISQRRI 447
            ||.|.|  |:||.....|:. |:|| ..|...|.|.|.:|...|   :|:.  .:.::.:.....
  Fly   320 CSYEGD--CVEVKRLEEPQG-WVDI-STPKCLSTGKSCIFGYFI---DNWH--QVWNLDLETGLN 375

  Fly   448 SVISHGRYEVTKILCWDTINHKVYFMATQDKKPGQRHLYSVQDPIHDDIRKVEPQCITCDLGDDL 512
            |..|.|.:.|..:..:|....|:|:.||....|...|::|            ..:|::|...|..
  Fly   376 SWQSRGNFTVLSVYGYDEARDKLYYQATLPGDPSVYHVFS------------NDECLSCGQIDAD 428

  Fly   513 WSSRYYYTNCTHFEAFITPSLGVATNYGIEFYILECQGPGLPVSGVHMQTTHSLVKILYDTRPFY 577
            .::      |.......:.|        ..:|.|.|.||....:.:...:|.:| ::.::....|
  Fly   429 GAA------CRSASGTFSKS--------FSYYTLSCTGPNPSYTRIFEASTKTL-QVDWEPNTAY 478

  Fly   578 TERLQKLALPTQRSFEVPLPHGGRAQVQLLLPPSWREELRDAAFPVIVEVNGRPGSESVSEKFKI 642
            .:::::...|:.|...|.|..|.....:|.|||::.|..:   :|:||.|...|.|..|:..|.:
  Fly   479 RKQIEEKLRPSYRFMNVTLADGSIGYAKLALPPNFVETKK---YPLIVVVYQGPNSVRVTNGFTL 540

  Fly   643 DWGTYMSSRNDVVYIRLDVRGSKGQSKKTLY---RHLGGVEVLDQISVIGYLLDTIGFLDETRVG 704
            .:..::::..|.:|..:|.||:..:.|..|:   ..||..||.||:.|..::...:.|:|..|.|
  Fly   541 GYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNLAFVDAERCG 605

  Fly   705 MWGWGYGGYVTSMALGTQQD-VFKCGIAVSPTADWLY--STFTERILGLPA--ENFKGYVEADAT 764
            :|||.||||:|:..:....| ||:||::|:|...|||  :.:|||.:|||.  :|.|.|.|:...
  Fly   606 IWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTSWLYYDTIYTERYMGLPTDDDNLKKYNESSVF 670

  Fly   765 QRARLIKSNSYFLIHGLADTTAPFVHGVQLAKSLTSANILFRYQTYADEGHDLSGVLEHVYSSME 829
            ......||:.:.||||..|....:.|.:.|||.|...:|.|..|||.||.|.:...|.|:|.:::
  Fly   671 GNLENFKSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQFEEQTYTDENHGIGNALPHLYHTID 735

  Fly   830 QYFAECLSLD 839
            .::..||:||
  Fly   736 AFWTNCLNLD 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17684	NP_001015352.3	DPPIV_N	147..554	CDD:279298	115/408 (28%)
CG17684	NP_001015352.3	Abhydrolase	643..836	CDD:304388	69/200 (35%)
CG11034	NP_001285638.1	DPPIV_N	103..457	CDD:279298	115/409 (28%)
CG11034	NP_001285638.1	Peptidase_S9	538..745	CDD:278741	72/206 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	78	1.000	Domainoid score	I5682
eggNOG	1	0.900	-	-		E1_COG1506
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1947
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D269253at2759
OrthoFinder	1	1.000	-	-		FOG0000419
OrthoInspector	1	1.000	-	-		mtm9241
orthoMCL	1	0.900	-	-		OOG6_100574
Panther	1	1.100	-	-	P	PTHR11731
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X274
	10	9.870