Protein Alignment CG17684 and Dpp8

DIOPT Version :10

• Sequence 1: NP_001015352.3
• Gene: CG17684 / 3355066
• FlyBaseID: FBgn0263780
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001381020.1
• Gene: Dpp8 / 315758
• RGDID: 1310901
• Length: 892
• Species: Rattus norvegicus
• Alignment Length: 752
• Identity: 183/752 - (24%)
• Similarity: 285/752 - (37%)
• Gaps: 215/752 - (28%)

  Fly   209 IIFVVKNDIFIRQSPLV-EEDIRIT------SSGHENHIYNGVPDWLYQEEI------FETPEAI 260
            |.|:..|||:|  |.|| .|:.|:|      :|..|:....||..::.|||.      :..|:|.
  Rat   222 IAFIHSNDIWI--SNLVTREERRLTYVHNELASMEEDPRSAGVATFVLQEEFDRYSGYWWCPQAE 284

  Fly   261 WTSSDG--THFMYALFNDTNVGM--MTYPWLSSGALFSGSGIFSGSIFPETKMV---RFPTPGTT 318
            .|.|.|  ...:|...:::.|.:  :|.|.|                  ||:..   |:|..||.
  Rat   285 RTPSGGKILRILYEENDESEVEIIHVTSPML------------------ETRRADSFRYPKTGTA 331

  Fly   319 NPEV-----------ELWAVDITNLSDIQKFNIKPPATIYGQDYYLTSAGWISDSNCQVSVVYMG 372
            ||:|           |...:|:.:...:|.|.|     ::....|:..|||..:.....|:: :.
  Rat   332 NPKVTFKMSEIVVDAEGGIIDVIDKELVQPFEI-----LFEGVEYIARAGWTPEGKYAWSIL-LD 390

  Fly   373 RSQNYSVISLCSK------EEDWKCLEVHSERAPE------------DEWLDIFPHPVF------ 413
            |||.:..|.|.|.      |:|....:...|..|:            |.|::|  |.:|
  Rat   391 RSQTHLQIVLISPELFIPVEDDAMDRQRLIESVPDSVTPLIIYEETTDIWINI--HDIFHVFPQT 453

  Fly   414 SSDGSSFLFLANIQES--ENYQFTHI----KHVMIS-------------QRRISVISHGRYEV-- 457
            ..|...|:|.:..:..  ..|:.|.|    |:...|             :..|::.| |.:||
  Rat   454 HEDEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITS-GEWEVLG 517

  Fly   458 ---TKILCW-DTINHKVYFMATQDKKPGQRHLYSVQDPIHDDIRKVEPQCITCDLGDDLWSSRYY 518
               :.|  | |.....|||..|:| .|.:.|||........|:.::              :.|.|
  Rat   518 RHGSNI--WVDEARKLVYFEGTKD-SPLEHHLYVTSYANPGDVVRL--------------TDRGY 565

  Fly   519 YTNC---THFEAFITPSLGVATNYGIEFY-------------------ILECQGPGLP------V 555
            ..:|   .|.:.||:......:.:.:..|                   ||:..|| ||      :
  Rat   566 SHSCCLSRHCDFFISKYSNQKSPHCVSLYKLSSPDDDPVHKTKEFWATILDSAGP-LPDYTPPEI 629

  Fly   556 SGVHMQTTHSLVKILYDTRPFYTERLQKLALPTQRSFEVPLPHGGRAQVQLLLPPSWREELRDAA 620
            ......|..:|..:||.                        ||.        |.|..:
  Rat   630 FSFESTTGFTLYGMLYK------------------------PHD--------LQPGKK------- 655

  Fly   621 FPVIVEVNGRPGSESVSEKFKIDWGTYMSSRNDV-----VYIRLDVRGS--KGQSKKTLYRH-LG 677
            :|.::.:.|.|..:.|:.:||   |......|.:     |.:.:|.|||  :|...:..::: :|
  Rat   656 YPTVLFIYGGPQVQLVNNRFK---GVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMG 717

  Fly   678 GVEVLDQISVIGYLLDTIGFLDETRVGMWGWGYGGYVTSMALGTQQDVFKCGIAVSPTADWL-YS 741
            .:|:.||:..:.||.....|:|..|||:.||.||||::.|||..:.|:|:..||.:|...|: |.
  Rat   718 QIEIDDQVEGLQYLASQYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYD 782

  Fly   742 T-FTERILGLPAENFKGYVEADATQRARLIKS--NSYFLIHGLADTTAPFVHGVQLAKSLTSANI 803
            | :|||.:|.|.:|.:||.......:|....|  |...|:||..|....|.|...|...|..|..
  Rat   783 TGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGK 847

  Fly   804 LFRYQTYADEGHDL----SGVLEHVYSSMEQYFAECL 836
            .:..|.|..|.|.:    ||  ||....:..|..|.|
  Rat   848 PYDLQIYPQERHSIRVPESG--EHYELHLLHYLQENL 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17684	NP_001015352.3	DPPIV_N	147..554	CDD:395744	100/446 (22%)
		Peptidase_S9	643..836	CDD:459761	66/208 (32%)
Dpp8	NP_001381020.1	Dpp_8_9_N	1..156	CDD:466112
		DPPIV_N	169..589	CDD:395744	95/412 (23%)
		Peptidase_S9	681..885	CDD:459761	66/204 (32%)