Protein Alignment CG17684 and Dpp10

DIOPT Version :10

• Sequence 1: NP_001015352.3
• Gene: CG17684 / 3355066
• FlyBaseID: FBgn0263780
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_950186.3
• Gene: Dpp10 / 269109
• MGIID: 2442409
• Length: 800
• Species: Mus musculus
• Alignment Length: 863
• Identity: 260/863 - (30%)
• Similarity: 430/863 - (49%)
• Gaps: 115/863 - (13%)

  Fly    20 PPDETLQVQDPKQKDHDFDFDEGHNWRSIILSLLVISFVVSGIVTAIYLLGYVDELLYWSGRRMI 84
            |.|:.|....|.|:          ||:.|.::|||| .||..::|...:|...|||...|..|:.
Mouse    21 PADQELGSNSPPQR----------NWKGIAIALLVI-LVVCSLITMSVILLTPDELTNSSETRLS 74

  Fly    85 LDEYLQGDLIPRRLPSSWVTTQKYVFQSDDGSLAVLDTTTNLVKVLVTNHTLRQLNVRRYLCSSD 149
            |:|.|............|:.....|:::::|.:..|:|.:|...:|:.|.|.......|:..|.|
Mouse    75 LEELLGKGFGLHNPEPRWINDTVVVYKTNNGHVMKLNTESNASTLLLDNSTFVTFKASRHSLSPD 139

  Fly   150 LKYVLFTHNVKKNFQKSFTAFYTIYDVTNDHHT-------PVKLKDTLKVQRTRLQYASWLGNTT 207
            |||||..::||:.|..||||.|.||::    ||       |.:::|::      ||||:|.....
Mouse   140 LKYVLLAYDVKQIFHYSFTASYLIYNI----HTGEVWELNPPEVEDSV------LQYAAWGVQGQ 194

  Fly   208 AIIFVVKNDIFIRQSPLVEEDIRITSSGHENHIYNGVPDWLYQEEIFETPEAIWTSSDGTHFMYA 272
            .:|::.:|:|:. |..:....:|:||||.|..|:||:.||||:||:..:..|.|.|.||....:.
Mouse   195 QLIYIFENNIYY-QPDIKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFL 258

  Fly   273 LFNDTNVGMMTYPWLSSGALFSGSGIFSGSIFPETKMVRFPTPGTTNPEVELWAVDITNLSDIQK 337
            :.||:.|..|..|            .|:|:::|:.|...:|..|..||.|:|:.|::  ......
Mouse   259 MINDSLVPNMIIP------------RFTGALYPKAKQYPYPKAGQANPSVKLYVVNL--YGPTHT 309

  Fly   338 FNIKPPATIYGQDYYLTSAGWISDSNCQVSVVYMGRSQNYSVISLCSKEEDWKCLEVHSERAPED 402
            ..:.||.....::||:|...|:  ||.:..|.::.|.||.|:::|| :.....|...:  ....|
Mouse   310 LELMPPDIFKSREYYITMVKWV--SNTRTVVRWLNRPQNISILTLC-ESTTGACSRKY--EMTSD 369

  Fly   403 EWLD-IFPHPVFSSDGSSFLFLANIQESENYQFTHIKHVMISQR--RISV--ISHGRYEVTKILC 462
            .||. ....||||.|||.|.....:::....:|.||...::..:  :|:|  ::.|.:||.:||.
Mouse   370 TWLSKQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQITVRHLTSGNWEVIRILA 434

  Fly   463 WDTINHKVYFMATQDKKPGQRHLY--SVQDPIHDDIRKVEPQCITCDLGDDLWSSRYYYTNCTHF 525
            :|....|:||::|:....| |.||  |.:..::.|       ||:|:         :...:||:|
Mouse   435 YDETTQKIYFLSTESSPQG-RQLYSASTEGLLNRD-------CISCN---------FMKEDCTYF 482

  Fly   526 EAFITPSLGVATNYGIEFYILECQGPGLPVSGVHMQTTHSLVKILYDTRPFYTERLQKLALPTQR 590
            :|..:|.        .:.::|.|:||.:||..:|: |.:.....|.:......|.:||..|..:.
Mouse   483 DASFSPM--------NQHFLLFCEGPKVPVVSLHI-TDNPSRYFLLENNSVMKETIQKKKLAKRE 538

  Fly   591 S-------FEVPLPHGGRAQVQLLLPPSWREELRDAAFPVIVEVNGRPGSESVSEKFKIDWGTYM 648
            :       :|:||        ||..|..:.|:.:   :.:::.::..||.:.|::||.:||.:.:
Mouse   539 TRILHIDDYELPL--------QLSFPKDFMEKNQ---YALLLIMDEEPGGQMVTDKFHVDWDSVL 592

  Fly   649 SSRNDVVYIRLDVRGSKGQSKKTL---YRHLGGVEVLDQISVIGYLLDTIGFLDETRVGMWGWGY 710
            ...::|:..|.|.|||..|..|.|   :|.:|.||..||::.:.|||.. .::|..|:.::|.||
Mouse   593 IDTDNVIVARFDGRGSGFQGLKVLQEIHRRIGSVEAKDQVAAVKYLLKQ-PYIDSKRLSIFGKGY 656

  Fly   711 GGYVTSMALGTQQDVFKCGIAVSPTADW-LY-STFTERILGLPAENFKGYVEADATQRARLIKSN 773
            |||:.||.|.:.:..||||..|:|.:|. || |.|:||.||:|::....|..:........:|..
Mouse   657 GGYIASMILKSDEKFFKCGAVVAPISDMKLYASAFSERYLGMPSKEESTYQASSVLHNIHGLKEE 721

  Fly   774 SYFLIHGLADTTAPFVHGVQLAKSLTSANILFRYQTYADEGHDLSGVLE-HVYSSMEQYFAECLS 837
            :..:|||.|||...|.|..:|.|.|..|.:.:..|.|.|||:.:|...: |.||::.::|::||
Mouse   722 NLLIIHGTADTKVHFQHSAELIKHLIKAGVNYTLQVYPDEGYHISDKSKHHFYSTILRFFSDCL- 785

  Fly   838 LDPDDTKPEVDNSIVPAE 855
                  |.||  |::|.|
Mouse   786 ------KEEV--SVLPQE 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17684	NP_001015352.3	DPPIV_N	147..554	CDD:395744	126/420 (30%)
		Peptidase_S9	643..836	CDD:459761	71/198 (36%)
Dpp10	NP_950186.3	DPPIV_N	137..503	CDD:395744	126/420 (30%)
		Peptidase_S9	584..786	CDD:459761	74/209 (35%)