DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17684 and SPAC14C4.15c

DIOPT Version :9

Sequence 1:	NP_001015352.3	Gene:	CG17684 / 3355066	FlyBaseID:	FBgn0263780	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_594920.2	Gene:	SPAC14C4.15c / 2542105	PomBaseID:	SPAC14C4.15c	Length:	853	Species:	Schizosaccharomyces pombe

Alignment Length:	896	Identity:	181/896 - (20%)
Similarity:	345/896 - (38%)	Gaps:	206/896 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LQVQDPKQKDHDFDFDEGHNWRSIILSLLVISFVVSGIVTAIYLLGYVDELLYWSGRRMIL---D 86
            ::.:..::|.|          |.|.|::.:. |:.|.:..||....|    |:.:.....|   |
pombe    54 IEAKKRRRKKH----------RYIYLAVCLF-FLASVLSCAIIFRFY----LHTNRENFSLFKND 103

  Fly    87 EYLQGD-----------LIPRRLPSSWVTTQKYVFQSDDGSLAVLDTTT--------------NL 126
            .|.|.:           .:|......|:|       |.:|::...|.:|              :.
pombe   104 SYKQKEPITVSHFGESIFLPYHQDIEWIT-------STEGTVLYYDQSTFSLSLFYPDGKEYGSN 161

  Fly   127 VKVLVTNHTLRQLNVRRYLCSSDLKYVLFTHNVKKNFQKSFTAFYTIYDVTNDHHTPVKLKDTLK 191
            |..|:|:..|...|:.|...|||::|:.|:.:..:.::.|:  :..:|.|   .....:::....
pombe   162 VDSLITSFVLTCKNLHRKRYSSDMEYIAFSCSKDRRWRHSY--YEDVYLV---ERATGRIEHLAS 221

  Fly   192 VQRTRLQYASWLGNTTAIIFVVKNDIFIRQSPLVEEDIRITSSGHENHIYNGVPDWLYQEEIFET 256
            .|..::..|.|......:::.:.:::||.:| ..|..:.||.....:.::||..||:|:|||.::
pombe   222 DQSKKIVVAEWSPIGHKLVYGLGSNLFIWES-FSEPPVCITDQSDLDGLFNGNSDWVYEEEILQS 285

  Fly   257 PEAIWTSSDGTHFMYALFNDTNVGMMTYPWLSSGALFSGSGIFSGSIFPETKMVRF---PTPGTT 318
            .:|:|.|.||....|...:|:.|.:...|:..          ....:..:.::..|   .||...
pombe   286 SKAVWWSPDGNCLSYLSIDDSKVPVHVLPFEQ----------LDSKVEDQNRVNNFFHYSTPKDP 340

  Fly   319 NPEVELWAVDITNLSD-IQKFNIKPPATIYGQDYYLTSAGWISDSNCQVSVVYMGRSQNY----S 378
            .|.|:|:....|:..: |:..:..|.:|   |..|:|...|..:.......|..|   ||    |
pombe   341 IPFVKLFVNCFTDSGESIEVDSSFPLST---QHRYITDVAWAGNEKLMFVEVLRG---NYERVTS 399

  Fly   379 VISLCSKEEDWKCLEVHSERAPEDEWLDIFPHPVFSSDG-----SSFLFLANIQESENYQFTHIK 438
            :..|.|::...:..|| ||            ||:..:..     .||..|.|::|      .:::
pombe   400 LFDLSSRKTTIENTEV-SE------------HPLALTSSLHLKYLSFESLGNLKE------RYVR 445

  Fly   439 HVMIS-QRRISVISHGRYEV-TKILCWDT------------INHKVYFMATQDKKPGQRHLYSVQ 489
            ...:| ::||::     ||: ..:..:.|            ||:.:||.|.....|..|
pombe   446 QYFLSNKKRIAI-----YELDNPVPIYLTPVNISFLSDLYLINNTLYFTAISSGSPFSR------ 499

  Fly   490 DPIHDDIRKVEPQCITCDLGDDLWSSRYYYTNCTHFEAFITPSLGVATNYGI---------EFYI 545
                                        .|..||  ::.|...:.:....|:         .:.:
pombe   500 ----------------------------VYRLCT--KSLILSEINIQIGSGLFGIKVSNDQNYLL 534

  Fly   546 LECQGPGLP---VSGVH-------------------MQTTHSLVKILYDTRPFYTERL----QKL 584
            :...||.:|   :..:|                   ..|:...||:.........|.|    :|.
pombe   535 VNYLGPEIPKQFIYSIHEDKVSTSNDHSKNNLPSDSSSTSLGKVKLELCNSLETNEELIITKEKF 599

  Fly   585 ALPTQRSFEVPLPHGGRAQVQLLLPPSWREELRDAAFPVIVEVNGRPGSESVSEKFKIDWGTYMS 649
            |.|:. .|:|.......|.:|.:.||::....|   :|.:..:.|.|.|..|:.|:::|....|:
pombe   600 AFPSV-FFKVIKVKNITAYIQEIRPPNFNPRKR---YPTVFHLYGAPQSALVTGKYEMDINELMA 660

  Fly   650 SRNDVVYIRLDVRGSKGQSKKTLYRHLGGVEVLDQISVIGYLLDTIGFLDETRVGMWGWGYGGYV 714
            |..:.:.|::|:......|.:.|:.....:.:...|.::...:|| .::|..|||:|||.:|||:
pombe   661 SVYNFLVIKVDIVDISDVSGQHLFSDSHELIIKSWIELLRSYVDT-PYIDRHRVGIWGWSFGGYL 724

  Fly   715 TSMALGTQQDVFKCGIAVSPTADWLY--STFTERILGLPAENFKGYVEADATQRA-RLIKSNSYF 776
            |...| ...|..|.|..|:|..||.|  :.::|.:||..::......:..|...: ...|.....
pombe   725 TLKIL-ENADFIKTGAVVAPVTDWRYYDAYYSENLLGAYSKQTTAIYDKTAVHYSENFRKLCGLL 788

  Fly   777 LIHGLADTTAPFVHGVQLAKSLTSANILFRYQTY--ADEGHDLSGVLEHVY 825
            ::||.:|......:.:||.|::....: :.|..:  .:..|:.|...::.:
pombe   789 VLHGTSDDNVHIENTMQLTKAMVEKGV-YNYYPFIVPNANHEFSDPTDYTF 838

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17684	NP_001015352.3	DPPIV_N	147..554	CDD:279298	86/442 (19%)
CG17684	NP_001015352.3	Abhydrolase	643..836	CDD:304388	44/188 (23%)
SPAC14C4.15c	NP_594920.2	DPPIV_N	182..543	CDD:279298	86/442 (19%)
SPAC14C4.15c	NP_594920.2	Abhydrolase	680..846	CDD:304388	38/162 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1506
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000419
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11731
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910