Protein Alignment CG17684 and Apeh

DIOPT Version :10

• Sequence 1: NP_001015352.3
• Gene: CG17684 / 3355066
• FlyBaseID: FBgn0263780
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_666338.2
• Gene: Apeh / 235606
• MGIID: 88041
• Length: 732
• Species: Mus musculus
• Alignment Length: 802
• Identity: 158/802 - (19%)
• Similarity: 260/802 - (32%)
• Gaps: 249/802 - (31%)

  Fly    90 QGDLIPRRLPSSWVTTQKYVFQSDDGSLAVLDTTTNLVKVLVTNHTLRQLNVRR----------- 143
            :|:|:.|..||.   |.|.|.:...|  ||.......::|...|..|:..|:..
Mouse    89 RGELLSRESPSG---TMKAVLRKAGG--AVSGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDD 148

  Fly   144 -YLC---SSDLKYVLFTHNVKKNFQKSFTAFYT-IYDVT---NDHHTPVKLKDTLKVQRTRLQYA 200
             :.|   |....::|:....|:...:||  |.| ..||:   .:...|.|....:|..:. :.|.
Mouse   149 CFGCLSWSHSETHLLYVAEKKRPKAESF--FQTKALDVSASDEEMARPKKPDQAIKGDQF-VFYE 210

  Fly   201 SWLGNTTAIIFVVKNDIFIRQSPLVEEDIRITSSGHENHIYNGVPDWLYQEEIFETPEAIWTSSD 265
            .| |.|     :|...|.:    |...||   .||:.: :..|||      |.....:|.|...|
Mouse   211 DW-GET-----MVSKSIPV----LCVLDI---ESGNIS-VLEGVP------ENVSPGQAFWAPGD 255

  Fly   266 GTHFMYALFNDTNVGMMTYPWLSSGALFSGSGIFSGSIFPETKMVRFPTPGTTNPEVELWAVDIT 330
                         .|::...|...               |....:|:    .||....|:.||::
Mouse   256 -------------TGVVFVGWWHE---------------PFRLGIRY----CTNRRSALYYVDLS 288

  Fly   331 N-----LSDIQKFNIKPPATIYGQDYYLTSAGWISDSNCQVSVVYMGRSQNYSVISLCSKEEDWK 390
            .     ||| :...:..|.              :|...|:  |||:
Mouse   289 GGKCELLSD-ESLAVCSPR--------------LSPDQCR--VVYL------------------- 317

  Fly   391 CLEVHSERAPEDEWLDIFPHPVFSSDGSSFLFLANIQESENYQFTHIKHVMIS--QRRISVISHG 453
                        ::..:.||...|.     |||.:       .:|.:..:::.  .|::.....|
Mouse   318 ------------QYPSLAPHHQCSQ-----LFLYD-------WYTKVTSLVVDIVPRQLGESFSG 358

  Fly   454 RY-EVTKILCWDTINHKVYFMATQDKKPGQRHLYSVQDPIHDDIRKVEPQ--------------- 502
            .| .:..:.||...:.:|.|.:.|..:              .|:..|:.|
Mouse   359 IYCSLLPLGCWSADSQRVVFDSVQRSR--------------QDLFAVDTQTGSVTSLTAGGSAGS 409

  Fly   503 --CITCDLGDDLWSSRYYYTNCTHFEAFITPSLGVATNYGIEFYILECQGPGLPVSGVHMQTTHS 565
              .:|.|  .||..::           |.||:|..:...|    .|...|....||.|.::....
Mouse   410 WKLLTID--RDLMVAQ-----------FSTPNLPPSLKVG----FLPPAGKEQSVSWVSLEEAEP 457

  Fly   566 LVKILYDTRPFYTERLQKLALPTQRSFEVPLPHGGRAQVQLLLPPSWREELRDAAFPVIVEVNGR 630
            :..|.:..|..:....|:........||.           :||.||...:  .:..|::|..:|.
Mouse   458 IPDIHWGIRVLHPPPDQENVQYADLDFEA-----------ILLQPSNSPD--KSQVPMVVMPHGG 509

  Fly   631 PGSESVSEKFKIDWGTY--MSSRNDVVYIRLDVRGSKG---QSKKTLYRHLGGVEVLDQISVIGY 690
            |.|..|:.     |..:  |..:.....:.::.|||.|   .|..:|..::|..:|.|....:..
Mouse   510 PHSSFVTA-----WMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVQQ 569

  Fly   691 LLDTIGFLDETRVGMWGWGYGGYVTSMALGTQQDVFKCGIAVSPT------------ADW-LYST 742
            :|....| |..||.:.|..:||:::...:|...:.:...||.:|.            .|| :..|
Mouse   570 VLQEEHF-DARRVALMGGSHGGFLSCHLIGQYPETYSACIARNPVINIVSMMGTTDIPDWCMVET 633

  Fly   743 FTERILGLPAENFKGYVEADATQRARLIKS---------NSYFLIHGLADTTAPFVHGVQLAKSL 798
                  |.|..|  .|:.........|.||         ....|:.|..|...||..|::...:|
Mouse   634 ------GFPYSN--DYLPDLNVLEEMLDKSPIKYIPQVKTPVLLMLGQEDRRVPFKQGLEYYHAL 690

  Fly   799 TSANILFRYQTYADEGHDLSGV 820
            .:.|:..|...|....|.||.|
Mouse   691 KARNVPVRLLLYPKSTHALSEV 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17684	NP_001015352.3	DPPIV_N	147..554	CDD:395744	77/435 (18%)
		Peptidase_S9	643..836	CDD:459761	47/205 (23%)
Apeh	NP_666338.2	APEH_N	<86..285	CDD:466026	53/255 (21%)
		TolB	277..>410	CDD:440585	31/206 (15%)
		DAP2	481..731	CDD:441115	59/259 (23%)