Protein Alignment CG17684 and Fap

DIOPT Version :10

• Sequence 1: NP_001015352.3
• Gene: CG17684 / 3355066
• FlyBaseID: FBgn0263780
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_032012.1
• Gene: Fap / 14089
• MGIID: 109608
• Length: 761
• Species: Mus musculus
• Alignment Length: 797
• Identity: 233/797 - (29%)
• Similarity: 392/797 - (49%)
• Gaps: 116/797 - (14%)

  Fly    81 RRMILDEYLQGDLIPRRLPSSWVTTQKYVFQSDDGSLAVLDTTTNLVKVLVTNHTLRQLNVRRYL 145
            |.:.|.:.|.|....:....:|::.|:|:.||:|.::...:..|....::::|.|::.:|...|.
Mouse    40 RALTLKDILNGTFSYKTYFPNWISEQEYLHQSEDDNIVFYNIETRESYIILSNSTMKSVNATDYG 104

  Fly   146 CSSDLKYVLFTHNVKKNFQKSFTAFYTIYDVTN-----DHHTPVKLKDTLKVQRTRLQYASWLGN 205
            .|.|.::|....:..|.::.|:||.|.|||:.|     .:..|           ..:||..|...
Mouse   105 LSPDRQFVYLESDYSKLWRYSYTATYYIYDLQNGEFVRGYELP-----------RPIQYLCWSPV 158

  Fly   206 TTAIIFVVKNDIFIRQSPLVEEDIRITSSGHENHIYNGVPDWLYQEEIFETPEAIWTSSDGTHFM 270
            .:.:.:|.:|:|:::|.| .:...:||.:|.||.|:||:|||:|:||:..|..|:|.|.||....
Mouse   159 GSKLAYVYQNNIYLKQRP-GDPPFQITYTGRENRIFNGIPDWVYEEEMLATKYALWWSPDGKFLA 222

  Fly   271 YALFNDTNVGMMTYPWLSSGALFSGSGIFSGSIFPETKMVRFPTPGTTNPEVELWAVDITNLSDI 335
            |..|||:::.::.|.:...|.            :|.|..:.:|..|..||.|.::.||.|....:
Mouse   223 YVEFNDSDIPIIAYSYYGDGQ------------YPRTINIPYPKAGAKNPVVRVFIVDTTYPHHV 275

  Fly   336 QKFNIKPPATIYGQDYYLTSAGWISDSNCQVSVVYMGRSQNYSVISLCSKEEDWKCLEVHSERAP 400
            ....:..|..|...|||.:...|:|..  :|.:.::.|.||.||:|:|...|||     |:...|
Mouse   276 GPMEVPVPEMIASSDYYFSWLTWVSSE--RVCLQWLKRVQNVSVLSICDFREDW-----HAWECP 333

  Fly   401 EDE---------WLDIF--PHPVFSSDGSSFLFLANIQESENYQFTHIKHVMISQRRISVISHGR 454
            :::         |...|  ..|.||.|.:|:..:  ..:.:.|:  ||.::..:......|:.|:
Mouse   334 KNQEHVEESRTGWAGGFFVSTPAFSQDATSYYKI--FSDKDGYK--HIHYIKDTVENAIQITSGK 394

  Fly   455 YEVTKILCWDTINHKVYFMATQDK----------KPGQRHLYSVQDPIHDDIRKVEP--QCITCD 507
            :|...|           |..|||.          .||:|::|.:      .|....|  :|:||.
Mouse   395 WEAIYI-----------FRVTQDSLFYSSNEFEGYPGRRNIYRI------SIGNSPPSKKCVTCH 442

  Fly   508 LGDDLWSSRYYYTNCTHFEAFITPSLGVATNYGIEFYILECQGPGLPVSGVHMQTTHSLVKILYD 572
            |..:         .|.::.|        :.:|..::|.|.|.|||||:|.:|...|...:::|.:
Mouse   443 LRKE---------RCQYYTA--------SFSYKAKYYALVCYGPGLPISTLHDGRTDQEIQVLEE 490

  Fly   573 TRPFYTERLQKLALPTQRSFEV-PLPHGGRA-QVQLLLPPSWREELRDAAFPVIVEVNGRPGSES 635
            .:.. ...|:.:.||   ..|: .|..||.. ..:::|||.:.   |...:|::::|.|.|.|:|
Mouse   491 NKEL-ENSLRNIQLP---KVEIKKLKDGGLTFWYKMILPPQFD---RSKKYPLLIQVYGGPCSQS 548

  Fly   636 VSEKFKIDWGTYMSSRNDVVYIRLDVRGSKGQSKKTL---YRHLGGVEVLDQISVIGYLLDTIGF 697
            |...|.::|.||::|:..:|...:|.||:..|..|.|   ||.||..||.||::.:...:: :||
Mouse   549 VKSVFAVNWITYLASKEGIVIALVDGRGTAFQGDKFLHAVYRKLGVYEVEDQLTAVRKFIE-MGF 612

  Fly   698 LDETRVGMWGWGYGGYVTSMALGTQQDVFKCGIAVSPTADWLY--STFTERILGLPA--ENFKGY 758
            :||.|:.:|||.|||||:|:||.:...:|||||||:|.:.|.|  |.::||.:|||.  :|.:.|
Mouse   613 IDEERIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASIYSERFMGLPTKDDNLEHY 677

  Fly   759 VEADATQRARLIKSNSYFLIHGLADTTAPFVHGVQLAKSLTSANILFRYQTYADEGHDLSG--VL 821
            ..:....||...::..|.||||.||....|.:..|:||:|.:|.:.|:...|:|:.|.:|.  ..
Mouse   678 KNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGISSGRSQ 742

  Fly   822 EHVYSSMEQYFAECLSL 838
            .|:|:.|..:..:|.||
Mouse   743 NHLYTHMTHFLKQCFSL 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17684	NP_001015352.3	DPPIV_N	147..554	CDD:395744	114/434 (26%)
		Peptidase_S9	643..836	CDD:459761	76/201 (38%)
Fap	NP_032012.1	DPPIV_N	106..473	CDD:395744	115/435 (26%)
		Peptidase_S9	553..757	CDD:459761	77/204 (38%)