Protein Alignment CG17684 and Dpp6

DIOPT Version :10

• Sequence 1: NP_001015352.3
• Gene: CG17684 / 3355066
• FlyBaseID: FBgn0263780
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_997165.2
• Gene: Dpp6 / 13483
• MGIID: 94921
• Length: 859
• Species: Mus musculus
• Alignment Length: 882
• Identity: 266/882 - (30%)
• Similarity: 431/882 - (48%)
• Gaps: 128/882 - (14%)

  Fly    11 GGGGGSWRL--------PPDETLQVQDPKQKDHDFDFDEGHNWRSIILSLLVISFVVSGIVTAIY 67
            ||.||..|.        ..::.|...:|.|:          ||:.|.::||||..:.|.|||::.
Mouse    55 GGAGGRPRFQYQARSDCDEEDELVGSNPPQR----------NWKGIAIALLVILVICSLIVTSVI 109

  Fly    68 LLGYVDELLYWSGRRMILDEYLQGDLIPRRLPSSWVTTQKYVFQSDDGSLAVLDTTTNLVKVLVT 132
            ||...::......:::.:::....|.......:.|::.::::::...||:.:.:..||...||:.
Mouse   110 LLTPAEDTSLSQKKKVTVEDLFSEDFKIHDPEAKWISNKEFIYRERKGSVILRNVETNNSTVLIE 174

  Fly   133 NHTLRQLNVRRYLCSSDLKYVLFTHNVKKNFQKSFTAFYTIYDVTNDHHTPVKLKDTLKVQRTRL 197
            ...:..|...||..|.|.:||||::||:..:|.|.|.:|.:..:  .|..|..| |..:|...:|
Mouse   175 GKKIESLRAIRYEISPDKEYVLFSYNVEPVYQHSHTGYYVLSKI--PHGDPQSL-DPPEVSNAKL 236

  Fly   198 QYASWLGNTTAIIFVVKNDIFIRQSPLVEEDIRITSSGHENHIYNGVPDWLYQEEIFETPEAIWT 262
            |||.|......:||:.:|:|:. .:.:.::.||:.|:|.|..||||:.||||:|||.::..|.|.
Mouse   237 QYAGWGPKGQQLIFIFENNIYY-CAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKSHIAHWW 300

  Fly   263 SSDGTHFMYALFNDTNVGMMTYPWLSSGALFSGSGIFSGSIFPETKMVRFPTPGTTNPEVELWAV 327
            |.|||...||..||:.|.:|..|            .::||::|..|...:|..|:.||.:.|..:
Mouse   301 SPDGTRLAYATINDSRVPLMELP------------TYTGSVYPTVKPYHYPKAGSENPSISLHVI 353

  Fly   328 DITN-LSDIQKFNIKPPATIYGQDYYLTSAGWISDSNCQVSVVYMGRSQNYSVISLCSKEEDWKC 391
            .:.. ..|::   :.||.....::||:|...|.:.:  :|:|.::.|:||.|:::||..... .|
Mouse   354 GLNGPTHDLE---MMPPDDPRMREYYITMVKWATST--KVAVTWLNRAQNVSILTLCDATTG-VC 412

  Fly   392 LEVHSERAPEDEWLDIFPH-----PVFSSDGSSFLFLANIQESENYQFTHIKHVMISQ-----RR 446
            .:.|.:.:  :.||    |     ||||.||..|.|:..|.:....:|.||. |..||     ..
Mouse   413 TKKHEDES--EAWL----HRQNEEPVFSKDGRKFFFVRAIPQGGRGKFYHIT-VSSSQPNSSNDN 470

  Fly   447 ISVISHGRYEVTKILCWDTINHKVYFMATQDKKPGQRHLYSVQDPIHDDIRKVEPQCITCDLGDD 511
            |..|:.|.::|||||.:|...:|:||::|:| .|.:|||||....  ||..:   ||::|||.:
Mouse   471 IQSITSGDWDVTKILSYDEKRNKIYFLSTED-LPRRRHLYSANTV--DDFNR---QCLSCDLVE- 528

  Fly   512 LWSSRYYYTNCTHFEAFITPSLGVATNYGIEFYILECQGPGLPVSGVHMQTTHSLVKILYDTRPF 576
                     |||:..|        :.::.::|::|:|:|||:|...||..|         |.|..
Mouse   529 ---------NCTYVSA--------SFSHNMDFFLLKCEGPGVPTVTVHNTT---------DKRRM 567

  Fly   577 Y----TERLQKLALPTQ------RSFEV---PLPHGGRAQVQLLLPPSWREELRDAAFPVIVEVN 628
            :    .|.:||.....|      |..||   .||      :|:|.|.::.:   .|.:|:::.|:
Mouse   568 FDLEANEEVQKAINDRQMPKIEYRKIEVEDYSLP------MQILKPATFTD---TAHYPLLLVVD 623

  Fly   629 GRPGSESVSEKFKIDWGTYMSSRNDVVYIRLDVRGSKGQSKKTLY---RHLGGVEVLDQISVIGY 690
            |.|||:||:|:|::.|.|.:.|.:..|.::.|.|||..|..|.|.   |.||.:|..||:..:..
Mouse   624 GTPGSQSVTERFEVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLQEVRRRLGFLEEKDQMEAVRT 688

  Fly   691 LLDTIGFLDETRVGMWGWGYGGYVTSMAL----GTQQDVFKCGIAVSPTADW-LY-STFTERILG 749
            :|.. .::|:|||.::|..||||:::..|    ..|...|.||.|:||..|: || |.|:||.||
Mouse   689 MLKE-QYIDKTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLG 752

  Fly   750 LPAENFKGYVEADATQRARLIKSNSYFLIHGLADTTAPFVHGVQLAKSLTSANILFRYQTYADEG 814
            |...:.:.|.......|...::...:.:||..||....|.|..:|...|......:..|.|.||.
Mouse   753 LHGLDNRAYEMTKLAHRVSALEDQQFLIIHATADEKIHFQHTAELITQLIKGKANYSLQIYPDES 817

  Fly   815 HDLSGVL--EHVYSSMEQYFAECLSLD---PDDTKPE 846
            |....|.  :|:..|:..:|.||..:.   |..|..|
Mouse   818 HYFHSVALKQHLSRSIIGFFVECFRVQDKLPTATAKE 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17684	NP_001015352.3	DPPIV_N	147..554	CDD:395744	136/417 (33%)
		Peptidase_S9	643..836	CDD:459761	65/203 (32%)
Dpp6	NP_997165.2	DPPIV_N	189..555	CDD:395744	136/418 (33%)
		Peptidase_S9	635..841	CDD:459761	66/206 (32%)