Protein Alignment CG17684 and Dpp4

DIOPT Version :10

• Sequence 1: NP_001015352.3
• Gene: CG17684 / 3355066
• FlyBaseID: FBgn0263780
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_034204.1
• Gene: Dpp4 / 13482
• MGIID: 94919
• Length: 760
• Species: Mus musculus
• Alignment Length: 819
• Identity: 257/819 - (31%)
• Similarity: 417/819 - (50%)
• Gaps: 89/819 - (10%)

  Fly    45 WRSIILSLLVISFVVSGIVTAIYLLGYVDELLYWSGRRMILDEYLQGDLIPRRLPSSWVTTQKYV 109
            |: ::|.||.::.:|:.|...|.||. .||....|.|...|.:||:.....:.....||:..:|:
Mouse     5 WK-VLLGLLGVAALVTIITVPIVLLS-KDEAAADSRRTYSLADYLKSTFRVKSYSLWWVSDFEYL 67

  Fly   110 FQSDDGSLAVLDTTTNLVKVLVTNHTLRQLNVRRYLCSSDLKYVLFTHNVKKNFQKSFTAFYTIY 174
            ::.:: ::.:|:.......:.:.|.|......  :..|.|..:||..:|..|.::.|:||.|.||
Mouse    68 YKQEN-NILLLNAEHGNSSIFLENSTFESFGY--HSVSPDRLFVLLEYNYVKQWRHSYTASYNIY 129

  Fly   175 DVTNDH-HTPVKLKDTLKVQRTRLQYASWLGNTTAIIFVVKNDIFIRQSPLVEEDIRITSSGHEN 238
            ||.... .|..|:.:       ..|:.:|......:.:|.||||:::..|.:... ||||:|.||
Mouse   130 DVNKRQLITEEKIPN-------NTQWITWSPEGHKLAYVWKNDIYVKVEPHLPSH-RITSTGEEN 186

  Fly   239 HIYNGVPDWLYQEEIFETPEAIWTSSDGTHFMYALFNDTNVGMMTYPWLSSGALFSGSGIFSGSI 303
            .||||:.||:|:||:|....|:|.|.:.|...||.||||.|.::.|.:.|..:|          .
Mouse   187 VIYNGITDWVYEEEVFGAYSALWWSPNNTFLAYAQFNDTGVPLIEYSFYSDESL----------Q 241

  Fly   304 FPETKMVRFPTPGTTNPEVELWAVDITNLSDIQK---FNIKPPATIYGQDYYLTSAGWISDSNCQ 365
            :|:|..:.:|..|..||.|:.:.|:|.:||....   ..|..||::...|:||....|.::.  :
Mouse   242 YPKTVWIPYPKAGAVNPTVKFFIVNIDSLSSSSSAAPIQIPAPASVARGDHYLCDVVWATEE--R 304

  Fly   366 VSVVYMGRSQNYSVISLCSKEE---DWKC--LEVHSERAPEDEWLDIF----PHPVFSSDGSSFL 421
            :|:.::.|.|||||:::|..::   .|.|  .:.|.|.:... |:..|    ||  |:||||||.
Mouse   305 ISLQWLRRIQNYSVMAICDYDKINLTWNCPSEQQHVEMSTTG-WVGRFRPAEPH--FTSDGSSFY 366

  Fly   422 FLANIQESENYQFTHIKHVMISQRRISVISHGRYEVTKI--LCWDTINHKVYFMATQDKK-PGQR 483
            .:  |.:.:.|:  ||.|....::..:.|:.|.:||..|  |..|.:    |:::.|.|: ||.|
Mouse   367 KI--ISDKDGYK--HICHFPKDKKDCTFITKGAWEVISIEALTSDYL----YYISNQYKEMPGGR 423

  Fly   484 HLYSVQDPIHDDIRKVEPQCITCDLGDDLWSSRYYYTNCTHFEAFITPSLGVATNYGIEFYILEC 548
            :||.:|...|.:::     |::|||..:         .|.::        .|:.:...::|.|.|
Mouse   424 NLYKIQLTDHTNVK-----CLSCDLNPE---------RCQYY--------AVSFSKEAKYYQLGC 466

  Fly   549 QGPGLPVSGVHMQTTHSLVKILYDTRPFYTERLQKLALPTQRSFEVPLPHGGRAQVQLLLPPSWR 613
            .|||||:..:|..|.|..:::|.|.... ...||.:.:|:::...:.| :..|...|::|||.:.
Mouse   467 WGPGLPLYTLHRSTDHKELRVLEDNSAL-DRMLQDVQMPSKKLDFIVL-NETRFWYQMILPPHFD 529

  Fly   614 EELRDAAFPVIVEVNGRPGSESVSEKFKIDWGTYMSSRNDVVYIRLDVRGSKGQSKKTLY---RH 675
            :..:   :|::::|...|.|:.....|:::|.||::|..:::....|.|||..|..|.::   |.
Mouse   530 KSKK---YPLLLDVYAGPCSQKADASFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRR 591

  Fly   676 LGGVEVLDQISVIGYLLDTIGFLDETRVGMWGWGYGGYVTSMALGTQQDVFKCGIAVSPTADWLY 740
            ||.:||.|||......: .:||:|..||.:|||.||||||||.||:...||||||||:|.:.|.|
Mouse   592 LGTLEVEDQIEAARQFV-KMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEY 655

  Fly   741 --STFTERILGL--PAENFKGYVEADATQRARLIKSNSYFLIHGLADTTAPFVHGVQLAKSLTSA 801
              |.:|||.:||  |.:|...|..:....||...|...|.||||.||....|....|::|:|..|
Mouse   656 YDSVYTERYMGLPIPEDNLDHYRNSTVMSRAEHFKQVEYLLIHGTADDNVHFQQSAQISKALVDA 720

  Fly   802 NILFRYQTYADEGHDL--SGVLEHVYSSMEQYFAECLSL 838
            .:.|:...|.||.|.:  |...:|:||.|..:..:|.||
Mouse   721 GVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSL 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17684	NP_001015352.3	DPPIV_N	147..554	CDD:395744	130/422 (31%)
		Peptidase_S9	643..836	CDD:459761	81/201 (40%)
Dpp4	NP_034204.1	DPPIV_rep	36..56	CDD:465875	5/19 (26%)
		DPPIV_N	102..472	CDD:395744	130/422 (31%)
		Peptidase_S9	553..757	CDD:459761	82/204 (40%)