Protein Alignment Haspin and Haspin

DIOPT Version :10

• Sequence 1: NP_001015349.2
• Gene: Haspin / 3355064
• FlyBaseID: FBgn0046706
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_172416.2
• Gene: Haspin / 837468
• AraportID: AT1G09450
• Length: 599
• Species: Arabidopsis thaliana
• Alignment Length: 596
• Identity: 163/596 - (27%)
• Similarity: 263/596 - (44%)
• Gaps: 145/596 - (24%)

  Fly     4 ISKTKM----DFLEEGRWKDPFD--ELLD---SRTKLSKMNIVKQNVRVTYNIDSSVENSSYIEI 59
            |.|.|:    ||.:|..:....|  |||:   |..|.|...:.:|.|....::.:.:|  .::..
plant    97 IPKGKVVKAPDFQKEKEYFRDIDAFELLEESPSPNKSSTWTMGEQVVPEMPHLSTRLE--KWLIS 159

  Fly    60 KEPNHKNEPLT-----LEDCSI--KVYCPSD-----SISTPCDKRLGGTTGLF------ETDLS- 105
            |:.||...|.:     ||:.:|  :..|.:|     |:.|| ||...|.|.:|      :.:|:
plant   160 KKLNHTCGPSSTLSKILENSAIHQESVCDNDAFDSLSLKTP-DKSSAGNTSVFRLIPSCDENLAA 223

  Fly   106 ---PITRLKLEGVEDSRDKCADTNEADLYVNVEILFQNINSSPKKCSNFGKKRLSNLNKMVTAVH 167
               |:.::|:|.: |..|:.                               ||||
plant   224 EDVPVRKIKMESI-DLEDEL-------------------------------KRLS---------- 246

  Fly   168 PSISLNPGKWRKSLNNFIRSKITETNFTKKVERRSSICQDRKSLVLKGEHKFENKYEEDVLKYCH 232
                             :.|.:..|:            ||....:|            |:|..|.
plant   247 -----------------LTSDLIPTH------------QDFDQPIL------------DLLSACG 270

  Fly   233 QCTPLPFNTAY----EQHKLLNTKKIGEGAYGEVFRCSRNQEVLKDHISDIVLKIIPLEGSTVIN 293
            |..|..|..|:    |...::   |||||.|||.||...:           |.||:|::|...:|
plant   271 QMRPSNFIEAFSKFCEPESIV---KIGEGTYGEAFRAGSS-----------VCKIVPIDGDFRVN 321

  Fly   294 GEKQKTFSQILPEIIITKKMCSLRTSKTNSTN---GFVSIQKVSLVKGRYPPHFIKLWEKYDNEK 355
            ||.||...::|.|:|::..:..||..:|.:.|   .::..|.:.|.:|.|.|..||.||::|.:.
plant   322 GEVQKRADELLEEVILSWTLNQLRECETTAQNLCPTYIKTQDIKLCQGPYDPILIKAWEEWDAKH 386

  Fly   356 GSENDHPELFGDNQLFAVLELKFAGSDMANFKFLNSEQSYYALQQIILALAVGEEEYQFEHRDLH 420
            |||||||: |.:.|.:.:..|:..|.|:.:|..||.:::...|.|....|||.|..::|||||||
plant   387 GSENDHPD-FPEKQCYVMFVLEHGGKDLESFVLLNFDEARSLLVQATAGLAVAEAAFEFEHRDLH 450

  Fly   421 LGNILIEYTNKKHIVCTFKSSNLTLLSKGVNVTIIDYTLSRVTINDCCYFNDLSRDEELFQA-TG 484
            .||||:...|...:....:...:.:.:.||.::|||:||||:...:...|.||:.|..||:. .|
plant   451 WGNILLSRNNSDTLPFILEGKQVCIKTFGVQISIIDFTLSRINTGEKILFLDLTSDPYLFKGPKG 515

  Fly   485 DYQYDVYRMMRNELKNNWSSFSPKTNIIWLSYVIVKVLDSVKYKSINTKVHRMYIDKIKELKNII 549
            |.|.:.||.|:...::.|.....:||::||.| :|.:|.:.|....::|..|    :::.||..:
plant   516 DKQSETYRKMKAVTEDYWEGSFARTNVLWLIY-LVDILLTKKSFERSSKHER----ELRSLKKRM 575

  Fly   550 MTFESASHCAN 560
            ..:|||....:
plant   576 EKYESAKEAVS 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Haspin	NP_001015349.2	Protein Kinases, catalytic domain	225..547	CDD:473864	111/329 (34%)
Haspin	NP_172416.2	Protein Kinases, catalytic domain	265..586	CDD:473864	102/328 (31%)