Protein Alignment Haspin and IRAK2

DIOPT Version :9

• Sequence 1: NP_001015349.2
• Gene: Haspin / 3355064
• FlyBaseID: FBgn0046706
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001561.3
• Gene: IRAK2 / 3656
• HGNCID: 6113
• Length: 625
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 57/282 - (20%)
• Similarity: 95/282 - (33%)
• Gaps: 93/282 - (32%)

  Fly     9 MDFLEEGRWKDPFDELLDSRTKLSKMNIVK--QNVRVT-----------YNIDSSVENSSYIEIK 60
            ||.|.|..|.:....::...|:|.|:..::  |.|.:|           ..:...|:....:|:.
Human    20 MDALSEWDWMEFASYVITDLTQLRKIKSMERVQGVSITRELLWWWGMRQATVQQLVDLLCRLELY 84

  Fly    61 EP-----NHKNEPLTLEDCSIKVYCP----SDSISTPCDKRLGGTTGLFETDLSPITRLKLEGVE 116
            ..     |.|..|        ::.||    .||:..             |..|:...|
Human    85 RAAQIILNWKPAP--------EIRCPIPAFPDSVKP-------------EKPLAASVR------- 121

  Fly   117 DSRDKCADTNEADLYVNVEILFQNINSSPKKCSNFGKKRLSNLNKMVTAVHPSISLNPGKWRKSL 181
                |..|..|....|.: ..|....|||.:                  .|....|.|.:  :..
Human   122 ----KAEDEQEEGQPVRM-ATFPGPGSSPAR------------------AHQPAFLQPPE--EDA 161

  Fly   182 NNFIRSKITETNFTKKVERRSSICQDRKSLVLKGEHKFENKYEEDVLKYCHQCTPLPFNTAYEQH 246
            .:.:||.:..::.:|  :..:||.:..|.|.|.|:..|.:  |.||:    |.|. .||
Human   162 PHSLRSDLPTSSDSK--DFSTSIPKQEKLLSLAGDSLFWS--EADVV----QATD-DFN------ 211

  Fly   247 KLLNTKKIGEGAYGEVFRCSRN 268
               ..:||.:|.:.:|:|..|:
Human   212 ---QNRKISQGTFADVYRGHRH 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Haspin	NP_001015349.2	PKc_like	252..>426	CDD:304357	6/17 (35%)
		DUF3635	479..>545	CDD:289128
IRAK2	NP_001561.3	Death_IRAK2	3..91	CDD:176773	13/70 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..181		17/116 (15%)
		STKc_IRAK2	216..504	CDD:271059	5/15 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	510..540

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153084
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930