Protein Alignment Haspin and Irak1

DIOPT Version :10

• Sequence 1: NP_001015349.2
• Gene: Haspin / 3355064
• FlyBaseID: FBgn0046706
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_006229660.1
• Gene: Irak1 / 363520
• RGDID: 1563841
• Length: 711
• Species: Rattus norvegicus
• Alignment Length: 349
• Identity: 69/349 - (19%)
• Similarity: 111/349 - (31%)
• Gaps: 117/349 - (33%)

  Fly   155 RLSNLNKMVTAVHPSISL----------------------NPGKWRKSLNNFIRSKITETNFTKK 197
            :|.....::||.||..|:                      :|.|.:.|.:.|:......:....:
  Rat    91 QLLRARDIITAWHPPASVLPPSTGAPRPSSISAGSETEDWSPRKLQSSASTFLSPAFPGSQTHSE 155

  Fly   198 VERRSSICQDRKSLVLKGE--HKFENKYEEDVLKYCHQCTPLPF---------NTAYEQHKLLNT 251
            .|.......|.....|:..  ...:....|..:....:..|.||         .|.....:|
  Rat   156 SELLQVPLSDSLGPPLQSSAPSSIKQPSPESPVSGLQRARPSPFCWPFCEISQGTCNFSEEL--- 217

  Fly   252 KKIGEGAYGEVFRC-SRNQ----EVLKDHISDIVLKIIPLEGSTVINGEKQKTFSQILPEIIITK 311
             :||||.:|.|:|. .||.    :.||:. :|:...::  :.|.:...|:...|..  |.|:...
  Rat   218 -RIGEGGFGCVYRAVMRNTTYAVKRLKEE-ADLEWTVV--KQSFLTEVEQLSRFRH--PNIVDFA 276

  Fly   312 KMCSLRTSKTNSTNGFVSIQKVSLVKGRYPPHFIKLWEKYDNEKGSENDHPELFGDNQLFAVLEL 376
            ..|        :.:||     ..||.|..|             .||..|.            |.|
  Rat   277 GYC--------AESGF-----YCLVYGFLP-------------NGSLEDQ------------LHL 303

  Fly   377 KFAGSDMANFKFLNSEQSYYALQQIILALAVGEEEYQFEHRD----LHLGNILIEYTNKKHIVCT 437
            :....         |..|:.....|:|..|   ...||.|:|    :| |:|
  Rat   304 QTQAC---------SPLSWPQRLDILLGTA---RAIQFLHQDSPSLIH-GDI------------- 342

  Fly   438 FKSSNLTLLSKGVNVTIIDYTLSR 461
             ||||: ||.:.:...:.|:.|:|
  Rat   343 -KSSNV-LLDERLMPKLGDFGLAR 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Haspin	NP_001015349.2	Protein Kinases, catalytic domain	225..547	CDD:473864	56/255 (22%)
Irak1	XP_006229660.1	Death_IRAK1	17..100	CDD:260061	1/8 (13%)
		Protein Kinases, catalytic domain	219..522	CDD:473864	50/217 (23%)