DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Haspin and ZK177.2

DIOPT Version :9

Sequence 1:	NP_001015349.2	Gene:	Haspin / 3355064	FlyBaseID:	FBgn0046706	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_495058.1	Gene:	ZK177.2 / 191236	WormBaseID:	WBGene00022670	Length:	296	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	55/250 - (22%)
Similarity:	112/250 - (44%)	Gaps:	49/250 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 VLKGEHKFENKYEEDVLKYCHQCTPLPFNTAYEQHKLLNTKKIGEGAYGEVFRCSRNQEVLKDHI 276
            |.||.||..|.    :::.......:|::.|..|.|    |.:|:||.|..:..     |.:|
Worm    29 VSKGRHKDVNA----IVRETESKKIVPWSDAKVQIK----KFLGDGASGTAYLV-----VWED-- 78

  Fly   277 SDIVLKIIPLEGSTVINGEKQKTFSQILPEIIITKKMCSLRTSKTNSTNGFVSIQKVSLVKGRYP 341
            .::|:|         :.|...::.|.:..|::||:|:..|    :.|.:.|:.... |:|....|
Worm    79 KEVVMK---------VTGIHPQSISVLHDELLITQKIGKL----SKSCHNFLPYHG-SIVISDLP 129

  Fly   342 PHFIKLWEKYDNEKGSE-NDHPELFGDNQLFAVLELKFAGSDMANFKFLNSEQSYYALQQIILAL 405
            ...:         :.|| .:|..:|          :.:.|:.:|:::..:..:....:.|::||:
Worm   130 AKMM---------RNSECVNHLAIF----------MGYGGTVLADWRTSDYRRCITIMAQLVLAM 175

  Fly   406 AVGEEEYQFEHRDLHLGNILIEYTNKKHIVCTFKSSNLTLLSKGVNVTIIDYTLS 460
            .:..::.:|.|.|:::.||||..|.|:.|........:|:.:.|:...:||::.|
Worm   176 RIANDKMKFVHGDIYMMNILIAPTTKRWIEYNIDGKTITIQTFGIIPQLIDFSKS 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Haspin	NP_001015349.2	PKc_like	252..>426	CDD:304357	35/174 (20%)
Haspin	NP_001015349.2	DUF3635	479..>545	CDD:289128
ZK177.2	NP_495058.1	SPS1	58..>263	CDD:223589	46/216 (21%)
ZK177.2	NP_495058.1	PKc_like	63..>196	CDD:304357	34/172 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1374355at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24419
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920