Protein Alignment Haspin and C04G2.10

DIOPT Version :10

• Sequence 1: NP_001015349.2
• Gene: Haspin / 3355064
• FlyBaseID: FBgn0046706
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001255462.1
• Gene: C04G2.10 / 182234
• WormBaseID: WBGene00007309
• Length: 322
• Species: Caenorhabditis elegans
• Alignment Length: 406
• Identity: 77/406 - (18%)
• Similarity: 162/406 - (39%)
• Gaps: 108/406 - (26%)

  Fly   168 PSISLNPGKWRKSLNNFI-RSKITETNFTKKVERRSSICQDRKSLVLKGEHK---FENKYEEDVL 228
            |..||      |...||: .:|..:.|...:|:.|..:.|.:..  .:.|:|   .|.|..:|..
 Worm     3 PIFSL------KIFQNFLFETKKKKMNAVAEVKGRRGVQQKKNE--KQNEYKRIGREKKLADDSR 59

  Fly   229 KYCH--QCTPLPFNTAYEQHKLLNTKKIGEGAYGEVFRCSRNQEVLKDHISDIVLKIIPLEGSTV 291
            .|.:  ........|.:.|.:|:...|:|||..|..::. :::..:|      .||::||..::
 Worm    60 CYGNILDLVKRKKVTNWTQTRLVVEGKLGEGLRGIAYKV-KHRNTMK------CLKLLPLSWTS- 116

  Fly   292 INGEKQKTFSQILPEIIITKKMCSLRTSKTNSTNGFVSIQKVSLVKGRYPPHFIKLWEKY--DNE 354
                :.|   :.|.:::      :||:.||        |:|.:       |:::..::.:  .|.
 Worm   117 ----RNK---EALEDLV------ALRSLKT--------IKKET-------PNYLTFFDSFVLTNL 153

  Fly   355 KGSEND-----HPELFGDNQLFAVLELKFAGSDMANFKFLNSEQSYYALQQIILALAVGEEEYQF 414
            ..|..|     .|:....:.|..::||  ..:.:.|.....:.:....::|::|:|.:.:.....
 Worm   154 PASTQDKLNQLDPQCPATHYLGLLVEL--GSNSLDNTMLTTAVEGLSIVKQLVLSLVIAKRRLDT 216

  Fly   415 EHRDLHLGNILIEYT-NKKHIVCTFKSSNLTLLSKGVNVTIIDYTLSRVTINDCCYFNDLSRDEE 478
            .|.|:|.||:|::.: :.|.:..|.....:.:.|.|:.|.|||::                 :..
 Worm   217 NHNDVHPGNVLVKRSASPKTLKYTLDGKVIRIPSHGLVVGIIDFS-----------------EAS 264

  Fly   479 LFQATGDYQYDVYRMMRNELKNNWSSFSPKTNIIWLSYV---IVKVLDSVKYKSINTKVHRMYID 540
            ..:|.|:                       :::.:||::   |.|.|...:.::..|.     ||
 Worm   265 FGRANGN-----------------------SDVGFLSFITEEISKTLSKAENRTFQTA-----ID 301

  Fly   541 KIKELKNIIMTFESAS 556
            .:.:.::|...:.:||
 Worm   302 GLTDARSITAIYPNAS 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Haspin	NP_001015349.2	Protein Kinases, catalytic domain	225..547	CDD:473864	59/334 (18%)
C04G2.10	NP_001255462.1	Protein Kinases, catalytic domain	<72..>265	CDD:473864	47/247 (19%)