DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Haspin and Y48B6A.10

DIOPT Version :9

Sequence 1:	NP_001015349.2	Gene:	Haspin / 3355064	FlyBaseID:	FBgn0046706	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_496965.1	Gene:	Y48B6A.10 / 175077	WormBaseID:	WBGene00012981	Length:	430	Species:	Caenorhabditis elegans

Alignment Length:	263	Identity:	56/263 - (21%)
Similarity:	105/263 - (39%)	Gaps:	44/263 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 KVERRSSICQDRKSLVLKGEHKFENKYEEDVLKYCHQCTPLPFNTAYEQHKLLNTKKIGEGAYGE 261
            |.||:.:..:.|::..|      |..:|:  ..|..:.|.......:...|:...:|:|.|..|:
Worm   146 KNERQRASERARRAKAL------EKDFEQ--FGYLPEMTTKKKVVQWPAMKIELEQKLGGGIAGD 202

  Fly   262 VFRCSRNQEVLKDHISDIVLKIIPLEGSTVINGEKQKTFSQILPEIIITKKMCSLRTSKTNSTNG 326
            .|.|:...       .:.|.|||||..|    ...:|.|.    |:....::..:    .:.|..
Worm   203 AFNCTWKG-------LERVAKIIPLHPS----HRNKKAFQ----EVAALNRLGDV----AHQTPN 248

  Fly   327 FVSIQKVSLVKGRYPPHFIKLWEKYDNEKGSENDHPELFGDNQLFAVLELKFAGSDMANF--KFL 389
            .|..:..::|.|.  |..:|            |...|.:..|.:..|: |...|..:|:.  ..|
Worm   249 LVKFEMAAVVTGM--PQDVK------------NQLRENWRTNHMLVVI-LSRGGRPVASQPPDSL 298

  Fly   390 NSEQSYYALQQIILALAVGEEEYQFEHRDLHLGNILIEYTNKKHIVCTFKSSNLTLLSKGVNVTI 454
            .::||...::|.::.:.:||...:..|.|.|..|:|:..|:.:::........:.:.|....:||
Worm   299 TAQQSIGIMKQFVMTMLIGETSLKLYHNDAHCRNVLLTDTDDEYLEYKPDGGAVKVKSYEKKLTI 363

  Fly   455 IDY 457
            ||:
Worm   364 IDF 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Haspin	NP_001015349.2	PKc_like	252..>426	CDD:304357	39/175 (22%)
Haspin	NP_001015349.2	DUF3635	479..>545	CDD:289128
Y48B6A.10	NP_496965.1	Pkinase_Tyr	189..>338	CDD:369480	40/182 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24419
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910