Protein Alignment Haspin and Irak2

DIOPT Version :9

• Sequence 1: NP_001015349.2
• Gene: Haspin / 3355064
• FlyBaseID: FBgn0046706
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_751893.3
• Gene: Irak2 / 108960
• MGIID: 2429603
• Length: 622
• Species: Mus musculus
• Alignment Length: 410
• Identity: 87/410 - (21%)
• Similarity: 137/410 - (33%)
• Gaps: 126/410 - (30%)

  Fly    74 CSIKV---------YCPSDSISTPCDKRLGGTTG--LF--ETDLSPITRLKLEGVE--DSRDKCA 123
            ||:|.         || |.|.|.|..:||.|..|  ||  |.|:       ::..|  |...:.:
Mouse   159 CSLKTDAPDSPQSKYC-STSTSAPKQERLLGLPGDRLFWSEADV-------VQATEDFDQSHRIS 215

  Fly   124 DTNEADLYV----NVEILFQNI----NSSPKKCSNFGKKRLSNLNKMVTA-VHPSISLNPGKWRK 179
            :...||:|.    .|...|:.:    .|||.....|.:..:....:...| |.|.:....|:...
Mouse   216 EGTFADIYQGQRNGVAFAFKKLREVAGSSPGSMDRFLQAEMQLCLRCCHANVLPLLGFCTGRQFH 280

  Fly   180 SL------NNFIRSKITETNFTKKV--ERRSSICQDRKSLVLKGEHK------FENKYEEDVL-- 228
            ||      |..:..::.....:..:  .:|:|||   ..|:|..||.      ..|....:||
Mouse   281 SLIYPYMANGSLHDRLWAQGNSDMLPWPQRASIC---SGLLLAVEHLHSLDIIHSNVKSANVLLD 342

  Fly   229 -----KYCHQCT-PLPFN----------------TAYEQHKLLN----TKKIGEGAYGEVFRCS- 266
                 |..|... |.|.|                .||.....:.    ||::      ::|.|.
Mouse   343 QHLNPKLAHPVAHPHPDNKKTKYTVMRTHLFQASAAYLPEHFIRVGQLTKQV------DIFSCGI 401

  Fly   267 RNQEVL-------KD----HISDIVLKIIPLEGSTVINGEKQKTFSQILPEIIITKKMCSLRTSK 320
            ...|||       ||    ::.|::|..||...|:|.:  ::.:..:     .:.|::|.....|
Mouse   402 VLAEVLTGIPAMDKDRSPVYLKDLLLSEIPNSTSSVCS--RKTSMGK-----AVVKEICQRHVEK 459

  Fly   321 --------------------TNSTNGFVSIQKVSL--VKGRYPPHFIKLWEKYDNEKGSENDHPE 363
                                ....|..|...:|||  |:.:........|.:.....||.::.||
Mouse   460 RAGLLPEACEEAWATAVSVCLRRRNASVEEARVSLAGVEEQLRGQLSLPWSRVSEATGSSSNTPE 524

  Fly   364 LFG--DNQLFAVLELKFAGS 381
            ...  ||...:|..|....|
Mouse   525 ETDDVDNSSLSVPSLVMMAS 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Haspin	NP_001015349.2	PKc_like	252..>426	CDD:304357	33/166 (20%)
		DUF3635	479..>545	CDD:289128
Irak2	NP_751893.3	Death_IRAK2	3..91	CDD:176773
		Pkinase	208..472	CDD:278497	53/279 (19%)
		PKc_like	214..502	CDD:304357	58/303 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..532		5/20 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..591

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843183
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930