Protein Alignment Haspin and haspin

DIOPT Version :10

• Sequence 1: NP_001015349.2
• Gene: Haspin / 3355064
• FlyBaseID: FBgn0046706
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_031759586.1
• Gene: haspin / 100496088
• XenbaseID: XB-GENE-29077271
• Length: 1278
• Species: Xenopus tropicalis
• Alignment Length: 568
• Identity: 185/568 - (32%)
• Similarity: 273/568 - (48%)
• Gaps: 119/568 - (20%)

  Fly    79 YCPSDSISTPCDKRLGGTTGLFETDLSPITRLKLEGVEDSRDKCADTNEADLYVNVEI------L 137
            :.|:|.......|||..         ||:    ||.:..:      .|.||.::.:::      .
 Frog   729 HLPTDPSGRKLHKRLCA---------SPL----LESITKT------PNLADSHIEIKVQSCRTRA 774

  Fly   138 FQNINSSPKKC-SNFGKKRLSNLNK---------------------------MVTAVHPS----- 169
            .:.:.:..|.| |.|..||..|..|                           :..|..||
 Frog   775 QETVGTGRKVCISGFSAKRWGNRLKKTRAQQQLSFRDSSDLSLRAFKELDPSLAAAQSPSSLLLS 839

  Fly   170 ----------------ISLNPG------------KW---RKSLNNFIRSKITETNFTKKVERRS- 202
                            :||:||            .|   |.:|:...:.|:..|........||
 Frog   840 SSLWNSSFMNSSAVMNMSLSPGTSGPRDPQRERRHWLRLRAALSLHRKKKVQATEPLIHPPERSL 904

  Fly   203 ------------SICQDRKSLVL-------KGEHKFENKYEEDVLKYCHQCTPLPFNTAYEQHKL 248
                        |:.....||:|       .|.....:  .|.|...|.|..|:||::...|.:|
 Frog   905 HFALYSPQSLNASLTLQTSSLLLLSSRCASAGADDLSD--AEKVYLECQQDGPIPFSSCLTQAQL 967

  Fly   249 LNTKKIGEGAYGEVFRCSRNQEVLKDHISDIVLKIIPLEGSTVINGEKQKTFSQILPEIIITKKM 313
            ..::||||||||||||..|.:       ..:.||:||:||:..:|||:||.||:|||||||:|::
 Frog   968 ACSQKIGEGAYGEVFRTFRGE-------LQVALKVIPIEGTHRVNGEEQKCFSEILPEIIISKEL 1025

  Fly   314 CSLRTSKTNSTNGFVSIQKVSLVKGRYPPHFIKLWEKYDNEKGSENDHPELFGDNQLFAVLELKF 378
            ..|...|.|.||||:|:.....|||.|||..::.|:::..|||:||:.|::|...|||.:||.:|
 Frog  1026 SLLNEGKENRTNGFISLHSAHCVKGCYPPELLRAWDQFAEEKGTENERPDMFSHEQLFMILEFEF 1090

  Fly   379 AGSDMANFKFLNSEQSYYALQQIILALAVGEEEYQFEHRDLHLGNILIEYTNKKHIVCTFKSSNL 443
            .|:|:.|.:..:...:...|.|:.:||||.|||.:|||||||.||:|||..:...|..:.....:
 Frog  1091 GGTDLENCQLPSVAVARSVLHQVTVALAVAEEELRFEHRDLHWGNLLIETCSSPTITASLHGDPI 1155

  Fly   444 TLLSKGVNVTIIDYTLSRVTINDCCYFNDLSRDEELFQATGDYQYDVYRMMRNELKNNWSSFSPK 508
            |:.:.||.|.||||||||:..:....|.|||.|||||...||.|:|:||.||.|.||.||::.|.
 Frog  1156 TIPTSGVQVKIIDYTLSRLDKDGLTVFCDLSADEELFLGEGDLQFDIYRAMREENKNAWSAYGPH 1220

  Fly   509 TNIIWLSYVIVKVLDSVKY-KSINTKVHRMYIDKIKELKNIIMTFESA 555
            :|::||.|:..|:|.:|:| :..::...|..:.|:::|:..|..|.||
 Frog  1221 SNVLWLHYLADKLLSAVRYTRKPSSAPQRRELRKLQDLRREIRKFGSA 1268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Haspin	NP_001015349.2	Protein Kinases, catalytic domain	225..547	CDD:473864	142/322 (44%)
haspin	XP_031759586.1	Protein Kinases, catalytic domain	940..1272	CDD:473864	146/338 (43%)