Protein Alignment eIF4B and NAM8

DIOPT Version :10

• Sequence 1: NP_001015319.1
• Gene: eIF4B / 3355041
• FlyBaseID: FBgn0020660
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_011954.1
• Gene: NAM8 / 856486
• SGDID: S000001128
• Length: 523
• Species: Saccharomyces cerevisiae
• Alignment Length: 292
• Identity: 56/292 - (19%)
• Similarity: 98/292 - (33%)
• Gaps: 68/292 - (23%)

  Fly     9 KKNKGTVISLQSFLCNSDAPVGTTQVSKKIRNLDGDDSDDGSGTL-------PLVYQLPTAPRAN 66
            |.|:|        .|..|.|..|...:..::|          |.|       .|.....|:..:|
Yeast   103 KNNQG--------YCFVDFPSSTHAANALLKN----------GMLIPNFPNKKLKLNWATSSYSN 149

  Fly    67 RIFDDNSIPHKAPFIAYINNLPFDANEDDLYEFFEGINLISLRLPRE---DGENGRSRGFGYVEL 128
            .....|::........::.:|..:..|..|:|.|  ||..:.....:   |...|.|:|:|:|:.
Yeast   150 SNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELF--INRYASTSHAKIVHDQVTGMSKGYGFVKF 212

  Fly   129 ENREDLIHVLS-LPDPSIKGRRIRIELSNENDQQSRQKSNRRFDGFGNNGDNRDSGNWRRDS--- 189
            .|.::....|| :....:.||.|::..::...|...          |||..||.|.:...::
Yeast   213 TNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVS----------GNNDYNRSSSSLNNENVDS 267

  Fly   190 ----------QNNGSNFGYSSNFERSFNRERKSLPDRDDVNTPGSWRTSARPQSIDTSPTRREVE 244
                      .|..:|.|:..|....|....:..|..:....|.:  |:.....:.:..|..|:.
Yeast   268 RFLSKGQSFLSNGNNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNN--TTVFIGGLSSLVTEDELR 330

  Fly   245 QVSEKYRE------------GRVKIADRYSRE 264
            ...:.:..            |.|:..||.|.|
Yeast   331 AYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAE 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4B	NP_001015319.1	RRM_eIF4B	78..159	CDD:409836	19/84 (23%)
NAM8	NP_011954.1	RRM1_NGR1_NAM8_like	55..144	CDD:410023	11/58 (19%)
		RRM2_SECp43_like	162..241	CDD:409781	19/80 (24%)
		RRM3_NGR1_NAM8_like	312..383	CDD:409782	9/53 (17%)