DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF4B and PHIP1

DIOPT Version :9

Sequence 1:	NP_001015319.1	Gene:	eIF4B / 3355041	FlyBaseID:	FBgn0020660	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_191094.1	Gene:	PHIP1 / 824700	AraportID:	AT3G55340	Length:	597	Species:	Arabidopsis thaliana

Alignment Length:	360	Identity:	74/360 - (20%)
Similarity:	124/360 - (34%)	Gaps:	106/360 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 QVSKKIRNLDGD---------DSDDGS-----------GTLPLV---YQLPTAPRANRIFDDNSI 74
            :|..|:|..||.         |::||:           |...|.   |...|.|         ||
plant   189 KVDCKMRPEDGAFSGIAFITFDTEDGAKRALAFDRAAMGDRYLTIQQYVKTTTP---------SI 244

  Fly    75 PHK------APFI------AYINNLPFDANEDDLYEFFEGINLISLRLPREDGENGRSRGFGYVE 127
            |.:      ||.:      .||.||.:|..|.|:.:.|....:.|:||.: :.|.|..:|:.:|:
plant   245 PRRKTSSGFAPEMVDGYNRVYIGNLAWDTTERDIRKLFSDCVINSVRLGK-NKETGEFKGYAHVD 308

  Fly   128 LENREDLIHVLSLPDPSIKGRRIRIELSNENDQQSRQKSNRRFDGFGNNGDNRDSGNWR------ 186
            .::...:...|.|....|.||.::|..:    .:.|..::.      ..|:..::|::.
plant   309 FKDSVSVAIALKLDQQVICGRPVKICCA----LKDRPATDH------TPGETNNAGSYNMEDTYA 363

  Fly   187 ----------RDSQNNGSNFG---YSSNFERSFNRE-------RKSLPDR-----DDVNTP-GSW 225
                      |...::|:.|.   .||..:|....|       ..:.|.:     |..|:. |..
plant   364 AADPVPALAGRSEVDDGNYFATTVSSSKVKRRVCYECGEKGHLSTACPIKLQKADDQANSKLGQE 428

  Fly   226 RTSARP--QSIDTSPTRREVEQVSEKYRE----------------GRVKIADRYSREETSKVEEE 272
            ....||  ||........:...::|.|..                |:||..:.|...|...:...
plant   429 TVDGRPAMQSYGLPKNSGDSYYMNETYASTNETYNGGYSASAVGTGKVKRRNCYECGEKGHLSTA 493

  Fly   273 RP-KLNLKPRTLPLPDVKTIEFEKCDVDEFNLDKQ 306
            .| ||.....|....|.:|:|.....|..::|.|:
plant   494 CPIKLQNTSHTNSTLDHQTVEAGPTQVTSYSLQKK 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF4B	NP_001015319.1	RRM	<72..268	CDD:223796	51/257 (20%)
eIF4B	NP_001015319.1	RRM_eIF4B	79..155	CDD:240848	22/81 (27%)
PHIP1	NP_191094.1	RRM	<129..327	CDD:223796	35/147 (24%)
		RRM1_PHIP1	163..234	CDD:240717	10/44 (23%)
		RRM2_PHIP1	263..334	CDD:240718	20/71 (28%)
		PTZ00368	393..592	CDD:173561	27/136 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910