DRSC/TRiP Functional Genomics Resources

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Protein Alignment eIF4B and TIAL1

DIOPT Version :10

Sequence 1:NP_001015319.1 Gene:eIF4B / 3355041 FlyBaseID:FBgn0020660 Length:459 Species:Drosophila melanogaster
Sequence 2:NP_001029097.1 Gene:TIAL1 / 7073 HGNCID:11804 Length:392 Species:Homo sapiens


Alignment Length:111 Identity:25/111 - (22%)
Similarity:49/111 - (44%) Gaps:12/111 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 FIAYINNLPFDANEDDLYEFFEGINLISLRLPREDGENGRSRGFGYVELENRED----LIHVLSL 140
            |..::.:|..:...:|:...|.....||.....:|...|:|:|:|:|...|:.|    ::|   :
Human   114 FHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVH---M 175

  Fly   141 PDPSIKGRRIRIELSNEND--QQSRQKSNR---RFDGFGNNGDNRD 181
            ....:.||:||...:....  .:|.|::|.   ||:...|....::
Human   176 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKN 221

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eIF4BNP_001015319.1 RRM_eIF4B 78..159 CDD:409836 19/82 (23%)
TIAL1NP_001029097.1 RRM1_TIAR 10..107 CDD:410028
RRM2_TIAR 113..192 CDD:410029 19/80 (24%)
RRM3_TIAR 222..294 CDD:241064 25/111 (23%)
Blue background indicates that the domain is not in the aligned region.

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