Protein Alignment eIF4B and eIF4H2

DIOPT Version :9

• Sequence 1: NP_001015319.1
• Gene: eIF4B / 3355041
• FlyBaseID: FBgn0020660
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_001263122.1
• Gene: eIF4H2 / 43645
• FlyBaseID: FBgn0039797
• Length: 459
• Species: Drosophila melanogaster
• Alignment Length: 398
• Identity: 79/398 - (19%)
• Similarity: 122/398 - (30%)
• Gaps: 171/398 - (42%)

  Fly    74 IPHKAPFIAYINNLPFDANEDDLYEFFEGINLISLRLPREDGENGRSRGFGYVELENREDLIHVL 138
            :|.:.|||||:.|||....:.|:.:.|....:.::||.: |.|....:|:||||.|....|...|
  Fly    57 VPTEPPFIAYVGNLPKGLVQGDVMKIFSDFEVKNVRLIK-DRETDEFKGYGYVEFETLAQLKSAL 120

  Fly   139 SLPDPSIKGR--------RIRIEL--------------------------------------SNE 157
                 :..||        .:||::                                      :|.
  Fly   121 -----NCNGRIKLDNFSAPLRIDIADHRRQNPGAPSGVGGAPPAGVGHERGGGVGRGGSTGAANG 180

  Fly   158 NDQQSRQKSNRRFD-----------------------------------------GF------GN 175
            |:...::::.||.|                                         ||      |.
  Fly   181 NNPYYQRRNYRRDDSVGSHQFRRREPRSNSSNHQMSNSSPTQSTTSINYNRTTRGGFNSRVAVGG 245

  Fly   176 NGDNRDSG-----NWRRDSQNNGSNFGYSSNFERSFNRE-------------RKSLPDRD----- 217
            ||:....|     |.|.|.|:.||. |:..|...:|||.             |...|.|:
  Fly   246 NGNRYQGGAPRNFNDREDQQSTGSG-GFQRNRTYNFNRSMNNSVGGGGAGVGRGGHPQRNFNGNG 309

  Fly   218 ------DVNTPGSWRTSARPQSIDT------------------------SPTRREVEQVSEKYRE 252
                  .||..|::....:.::.|.                        ......|...||....
  Fly   310 GGGGFGVVNGGGNYTNFVQNRNRDRRGHYNPNHSGSSGGYNNNGNNTFGGENNHPVHGASESASS 374

  Fly   253 GRVKIADRYSREETSKVEEERPKLNLKPRTLPLPDVKTIEFEKCDVDEFNLDKQGGTSSLNVFGS 317
            |   .....|.:...:.:::||||.|||||:..|           ::.....||...    :||.
  Fly   375 G---TGPSSSNQFAVRDDDDRPKLVLKPRTVTAP-----------INSLAETKQAAL----IFGK 421

  Fly   318 AKPVDTAA 325
            |||.|.::
  Fly   422 AKPRDDSS 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4B	NP_001015319.1	RRM	<72..268	CDD:223796	61/339 (18%)
		RRM_eIF4B	79..155	CDD:240848	26/121 (21%)
eIF4H2	NP_001263122.1	RRM	<58..247	CDD:223796	35/194 (18%)
		RRM_SF	62..140	CDD:302621	26/83 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466432
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1530583at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.850