DRSC/TRiP Functional Genomics Resources

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Protein Alignment eIF4B and drr-2

DIOPT Version :9

Sequence 1:NP_001015319.1 Gene:eIF4B / 3355041 FlyBaseID:FBgn0020660 Length:459 Species:Drosophila melanogaster
Sequence 2:NP_499818.1 Gene:drr-2 / 259546 WormBaseID:WBGene00011730 Length:207 Species:Caenorhabditis elegans


Alignment Length:241 Identity:61/241 - (25%)
Similarity:88/241 - (36%) Gaps:70/241 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 FIAYINNLPFDANEDDLYEFFEGINLISLRLPR------EDGENGRSRGFGYVELENREDLIHVL 138
            |.|:|..||:|:...|:....:........|.:      .|.::|..:||.||..||.:.:...:
 Worm     6 FKAFIGGLPYDSIATDIETILKHCKFTDEELKKFDIHLVHDRDSGSFKGFAYVTFENEQQMNTAI 70

  Fly   139 SLPDPSIKGRRIRIELSNENDQQSRQKSNR------RFDGFGNNGD-NRDSGNWRRDSQ----NN 192
            |    .:.|......:...|..|.|.:|:|      |...||:.|. .|.:|.:||..:    |.
 Worm    71 S----GLNGADFGNRVLKVNRAQQRDRSDRGGGRGGRGGNFGDRGGRGRGAGGFRRGGEGGRFNE 131

  Fly   193 GSNFGYSSNFERSFNRERKSLPDRDDVNTPGSWRTSARPQSIDTSPTRREVEQVSEKYREGRVKI 257
            |...|   .|....:|              |.:|            .|||.|             
 Worm   132 GERRG---GFGGGGHR--------------GGYR------------QRRESE------------- 154

  Fly   258 ADRYSREETSKVE---EERPKLNLKPRTLPLPDVKTIEFEKCDVDE 300
             :::..||||...   .|||:|||||||   .|...||..|...:|
 Worm   155 -EQHKAEETSDPSAPPAERPRLNLKPRT---TDAAEIEARKKQEEE 196

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eIF4BNP_001015319.1 RRM <72..268 CDD:223796 45/204 (22%)
RRM_eIF4B 79..155 CDD:240848 18/80 (23%)
drr-2NP_499818.1 RRM_SF 6..88 CDD:388407 19/85 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1530583at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1292
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.040

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