Protein Alignment eIF4B and H05C05.1

DIOPT Version :9

• Sequence 1: NP_001015319.1
• Gene: eIF4B / 3355041
• FlyBaseID: FBgn0020660
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_001367918.1
• Gene: H05C05.1 / 259329
• WormBaseID: WBGene00019157
• Length: 903
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 112/520 - (21%)
• Similarity: 173/520 - (33%)
• Gaps: 184/520 - (35%)

  Fly     2 ASAGKKGKKNKGTVISLQSFLCNSDAPVG-----------TTQVSKKIRNLDG--DDSDDGSGTL 53
            |.:...|.||      ||  :|  |.|.|           ..|.:|...:.||  :::|.|..|
 Worm    76 AESSANGSKN------LQ--VC--DEPFGGAVSWAQLMEEDEQFNKITDDDDGETEEADGGETT- 129

  Fly    54 PLVYQLPTAPRANRIFDDNSIPHKAPFIAYINNLPFDANEDDLYEFFEG---INLISLRLPREDG 115
                :..:..|..|    .:||.:.||...|.|:.....|::|..:|.|   |..:.:|  :|||
 Worm   130 ----ENSSPERRGR----RNIPTEPPFRVQITNISSQHVEEELIYYFGGESHIKRVDIR--KEDG 184

  Fly   116 ENGRSRGFGYVELE--NREDLIHVLSLPDPSIKGRRIRIELSNENDQQSRQKSNRRFDGFGNNGD 178
            .         .|.|  .|:.|:..|...|...|||.:::.:....:..:|..|......:|...:
 Worm   185 N---------AEFEYFTRDGLLLALKKQDVEFKGRVLKVFVRQNRESVARVTSRHSQQEYGRPYE 240

  Fly   179 NRD--------SGNWRR---DSQNN------------------------------------GSN- 195
            :.|        |.|:||   :|||:                                    |||
 Worm   241 SNDSHFSGKSSSQNYRRSHYNSQNSLNSDKHGRYDKGNRSNHYGTMPAGGFHDRRGGGSYRGSND 305

  Fly   196 --FGYSSNFE--RSFNRERKSLPDRDD--------VNTPGSWRTS-------------------- 228
              |..:.:|.  |:.|.:|::...|||        :...||::.:
 Worm   306 CRFNNNGSFRAPRNPNYDRQNSSGRDDYHHGNGGPLQRSGSYQHNHNHSNTKDYGRQYSNHNHYS 370

  Fly   229 -----ARPQSIDTSPTRREVEQVSEKYREGRVKIADRYSREETSKVEEERPKLNLKPRTLPLPDV 288
                 ..|.|| ::.:|.|....:..| :...:.:.|.|...|..|||             .|..
 Worm   371 NYHGGGGPGSI-SARSRTESHSTTNNY-DAFSRTSSRMSLAATGTVEE-------------TPQR 420

  Fly   289 KTIEFEKCDVDEFNLDKQGGTSSLNVFGSAKPVDTAARELEIEQRLALARKQDKGRREQGLNEKL 353
            |:               .||  ..|.||.||||||..|.||:|:|.....|:.|...........
 Worm   421 KS---------------TGG--GANPFGDAKPVDTETRLLELEKRRQEKEKEQKAAAAAAAAAAA 468

  Fly   354 AELQVDKNDNESL---------SATVSWR-------TNQDYKESDKINKCPGEKQRDEEIHRLNH 402
            |.......|:|::         |:|.|.|       ....|:.|....   |.....::.|:.||
 Worm   469 AAADPVAGDHENIVSDSTQASRSSTSSHRGFHGPPSHRGSYQGSSGRG---GGGYHQQQHHQYNH 530

  Fly   403  402
             Worm   531  530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4B	NP_001015319.1	RRM	<72..268	CDD:223796	57/285 (20%)
		RRM_eIF4B	79..155	CDD:240848	22/80 (28%)
H05C05.1	NP_001367918.1	RRM_SF	143..220	CDD:418427	23/87 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58965
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23236
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110