Protein Alignment eIF4B and sce3

DIOPT Version :9

• Sequence 1: NP_001015319.1
• Gene: eIF4B / 3355041
• FlyBaseID: FBgn0020660
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_595728.1
• Gene: sce3 / 2540528
• PomBaseID: SPBC18H10.04c
• Length: 388
• Species: Schizosaccharomyces pombe
• Alignment Length: 421
• Identity: 115/421 - (27%)
• Similarity: 167/421 - (39%)
• Gaps: 113/421 - (26%)

  Fly    12 KGTVISLQSFLCNSDAPVGTTQVSKKIRNLDGDDSDDGSGTLPLV-------YQLPTA------- 62
            |.|.:||.:||  .|...|:|..:..|.:|.....|..:.|....       |..|::
pombe     5 KSTKMSLNAFL--GDESFGSTNWADDIDDLPALPQDRTTSTYRATPSSADAGYNAPSSTFESVRS 67

  Fly    63 -PRANR--------IFDDNSIPHKAPFIAYINNLPFDANEDDLYEFF-EGINLISLRLPREDGEN 117
             |.:.|        ..|...||.:.||.|::.||.||..|:||.:|| ||:..|.|.:   |...
pombe    68 PPESRREGGMGSGYQRDAIPIPSEPPFTAHVGNLSFDLTENDLGDFFGEGVTSIRLVI---DPLT 129

  Fly   118 GRSRGFGYVELENREDLIHVLSLPDPSIKGRRIRIELSNENDQQSRQKSNRRFDGFGNNGDNRDS 182
            .|||||||||.|..:.|...|:|....:.||.:||.::......:|::              |.:
pombe   130 ERSRGFGYVEFETADTLSAALALSGEDLMGRPVRITVAEPRRSFAREE--------------RST 180

  Fly   183 GNWRRDSQNNGSNFGYSSNFERSFNRERKSLPDRDDVNTP-GSWRT-SARPQSIDTSPTRREVEQ 245
            |:|.|                      |..||..:...:| |..|| |.|.:.....|:.|..|:
pombe   181 GDWVR----------------------RGPLPPAEPAESPFGKRRTNSGRFRDPARDPSDRVREE 223

  Fly   246 VSEKYREGRVKIADRYSREETSKVEEERPKLNLKPR------TLPLPDVKTIEFEKCDVDEFNLD 304
            ..|..|.|.:.     .||.:     |||:||||||      |...|...|....|...|.
pombe   224 PREWVRRGPLP-----PRESS-----ERPRLNLKPRSSSNVNTEATPSATTTTSSKPKRDP---- 274

  Fly   305 KQGGTSSLNVFGSAKPVDTAARELEIEQRLALA----RKQDKGRREQGLNEKLAELQVDKND-NE 364
                      ||.|||||..:....:|::||..    |::|...||:..:.|.:..:.:|.| .:
pombe   275 ----------FGGAKPVDNTSVLQRVEEKLAKRTQSFRREDNANRERSTSRKPSADKAEKTDKTD 329

  Fly   365 SLSATVSWRTNQDYKESDKINKCPGEKQRDE 395
            :::..||     |.:..|      |||:..|
pombe   330 AIAEKVS-----DIRLGD------GEKKSSE 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4B	NP_001015319.1	RRM	<72..268	CDD:223796	58/198 (29%)
		RRM_eIF4B	79..155	CDD:240848	34/76 (45%)
sce3	NP_595728.1	RRM	1..255	CDD:223796	85/300 (28%)
		RRM_SF	95..169	CDD:302621	32/76 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	50	1.000	Domainoid score	I3394
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto102008
orthoMCL	1	0.900	-	-		OOG6_105219
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1292
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840