Protein Alignment Gprk1 and grk5l

DIOPT Version :9

• Sequence 1: NP_001036438.1
• Gene: Gprk1 / 3355013
• FlyBaseID: FBgn0260798
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_005167309.1
• Gene: grk5l / 567452
• ZFINID: ZDB-GENE-081105-95
• Length: 584
• Species: Danio rerio
• Alignment Length: 547
• Identity: 199/547 - (36%)
• Similarity: 293/547 - (53%)
• Gaps: 42/547 - (7%)

  Fly     3 DLEAVLADVSYLMAMEKSKCTPAARASKK----LNLPDPSVRSVMYKYLEKEGELNFHKIFNEVL 63
            :||.::|:...|.|.|........| |||    |..|..|..:.:.|.:|::......:   :.:
Zfish     2 ELENIVANTVLLKAREGGGGKRKGR-SKKWREILRFPHISQCTELNKAIERDYVCLCER---QPI 62

  Fly    64 GYLLFKDFCENDSEEPIQQLKFFEQIKLFEKTECY----DERKKMARDIYDNFIMEEMLSHTYEY 124
            |.|||:.:||...|  :|:.     |:|.:..:.|    ||::|...|......:.:..|...:.
Zfish    63 GRLLFRLYCETQPE--LQRC-----IQLLDAMDDYEVSPDEKRKSRGDEIIKKFLNKQSSECVDV 120

  Fly   125 SKHAVASVQKYLLKNEVPVDLFEPYLEEIFTQLKGKPFKKFLESDKFTRFCQWKNLELNIQLTMN 189
            :: ::|...|..|:.....::|....:.:...|.|.||..:..|..|.||.|||.||.. .:|.:
Zfish   121 AE-SLAERCKENLELSPCKEIFSDCRKALHDYLSGAPFTDYQNSMYFDRFLQWKMLERQ-PITKD 183

  Fly   190 DFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGEMLALNERNMLQAVSTGIDCPF 254
            .|..:|::|:||||||..|:...||||||.|.|:|||||.::||.:||||:.:|:.|::    .|
Zfish   184 TFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNS----RF 244

  Fly   255 IVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGI--FSEDEMKFYAAEVILGLEHMHKRCIVYR 317
            :|.:.||:.|.|.||.:|.:||||||.:|:...|.  |.::.::.||||:..|||.:|:..|:||
Zfish   245 VVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGTPGFEKERVQLYAAEICCGLEDLHRESIIYR 309

  Fly   318 DLKPANILLDENGHIRISDLGLACDFSKKKP-----HASVGTHGYMAPEVLSKGTSYDSCADWFS 377
            ||||.|||||:||||||||||||.    |.|     ...|||.|||||||:: ...|....||:.
Zfish   310 DLKPENILLDDNGHIRISDLGLAI----KVPDGEQIRGRVGTVGYMAPEVIN-NERYSMSPDWWG 369

  Fly   378 FGCMLYKLLKGHSPFRQHKTKDKLE-IDKMTLTMNVELPESFSLELKNLLEMLLQRDVSKRLGCM 441
            .||::|::..|.||||..|.:.|.| ::|.......|..:.||.:.|.:..|||.:|..:||||.
Zfish   370 LGCLIYEMTAGRSPFRARKERVKREDVEKRVQEEEEEYSDKFSEDTKAICRMLLSKDPKQRLGCQ 434

  Fly   442 GNGADEVKMHNFFCGIDWHQVYIQKYTPPLVPPRGEVNAADAFDIGSFDEEDTKGIKLNDADQDL 506
            .:.|..||.|.||..|::.::......|..||....|...|..||..|  ...||:.|:..|.|.
Zfish   435 TDRASGVKAHPFFKNINFKRLEAGILEPSFVPDPRAVYCKDVLDIEQF--STVKGVNLDQTDNDF 497

  Fly   507 YKMFSL-TISERWQQEVSET-VFDTVN 531
            |..|:. ::|..||.|:.|| .|:.:|
Zfish   498 YSKFATGSVSIPWQNEMIETECFNDLN 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gprk1	NP_001036438.1	RGS_GRK2_GRK3	30..186	CDD:188701	40/163 (25%)
		PKc_like	185..531	CDD:304357	150/355 (42%)
		Pkinase	191..454	CDD:278497	124/270 (46%)
		PH_GRK2_subgroup	552..675	CDD:269946
		PH	559..657	CDD:278594
grk5l	XP_005167309.1	RGS	35..178	CDD:295367	37/153 (24%)
		STKc_GRK4_like	184..468	CDD:270756	130/292 (45%)
		S_TKc	185..447	CDD:214567	124/270 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0986
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1104340at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820