Protein Alignment Gprk1 and grk5

DIOPT Version :9

• Sequence 1: NP_001036438.1
• Gene: Gprk1 / 3355013
• FlyBaseID: FBgn0260798
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_001017316.1
• Gene: grk5 / 550070
• XenbaseID: XB-GENE-1008485
• Length: 594
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 209/576 - (36%)
• Similarity: 308/576 - (53%)
• Gaps: 42/576 - (7%)

  Fly     3 DLEAVLADVSYLMAMEKSKCTPAARASKK----LNLPDPSVRSVMYKYLEKEGELNFHKIFNEVL 63
            :||.::|:...|.|.|........| |||    |..|..|....:.|.||::......|   :.:
 Frog     2 ELENIVANTVLLKAREGGGGKRKGR-SKKWKEILKFPHISQCEDLRKQLERDYTSLCEK---QPI 62

  Fly    64 GYLLFKDFCENDSEEPIQQLKFFEQIKLFEKTECYDERKKMARD-IYDNFIMEEMLSHTYEYSKH 127
            |..||:.||:. .|..::.:.|.:.:..:|.:.  ||::|...| |...|...|...:..|....
 Frog    63 GRRLFRQFCDT-REHFLRCINFLDAVADYEVSP--DEKRKETGDEIISRFFNPESSDYMPEIPDA 124

  Fly   128 AVASVQKYLLKNEVPVDLFEPYLEEIFTQLKGKPFKKFLESDKFTRFCQWKNLELNIQLTMNDFS 192
            .:....:.|.||. ..::|...:.::...|.|.||::|.:|..|.||.|||:||..: :|.:.|.
 Frog   125 YMEECSENLGKNP-SKEIFTKCISQLHEFLSGSPFREFQDSMYFDRFLQWKSLERQL-VTKDTFR 187

  Fly   193 VHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGEMLALNERNMLQAVSTGIDCPFIVC 257
            .:|::|:||||||..|:...||||||.|.|:|||||.::||.:||||:.:|:.|::    .|:|.
 Frog   188 QYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMALNEKQILEKVNS----RFVVS 248

  Fly   258 MTYAFHTPDKLCFILDLMNGGDLHYHLSQHGI--FSEDEMKFYAAEVILGLEHMHKRCIVYRDLK 320
            :.||:.|.|.||.:|.:||||||.:|:...|.  |.|:.:.|||||:..||||:|:..|||||||
 Frog   249 LAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERVVFYAAEICCGLEHLHQEGIVYRDLK 313

  Fly   321 PANILLDENGHIRISDLGLACDFSK-KKPHASVGTHGYMAPEVLSKGTSYDSCADWFSFGCMLYK 384
            |.|||||::|||||||||||....: :.....|||.|||||||: |...|....||:..||::|:
 Frog   314 PENILLDDDGHIRISDLGLAIKIPEGESIRGRVGTVGYMAPEVI-KNERYTFSPDWWGLGCLIYE 377

  Fly   385 LLKGHSPFRQHKTKDKL-EIDKMTLTMNVELPESFSLELKNLLEMLLQRDVSKRLGCMGNGADEV 448
            :::|.||||..|.:.|. |::|............|:.:.|::.::||.:|..:||||..:||.||
 Frog   378 MIEGQSPFRARKERVKREEVEKRVQEDEESYSAKFTEDAKSICKVLLTKDPKQRLGCKEHGAGEV 442

  Fly   449 KMHNFFCGIDWHQVYIQKYTPPLVPPRGEVNAADAFDIGSFDEEDTKGIKLNDADQDLYKMFSL- 512
            |.|.|...|.:.::......||.||....|...|..||..|  ...||:.|:..|.|.|..|:.
 Frog   443 KQHPFLRNIHFKRLEAGIMKPPFVPDPRAVYCKDVLDIEQF--STVKGVNLDQTDNDFYVKFATG 505

  Fly   513 TISERWQQEVSET-------VFDTVNTETDKLE-------QKRKLKQK--QHFDAD 552
            .:...||.|:.||       :|....|.:..|:       .||.|.|:  :..:||
 Frog   506 CVPIPWQNEMIETECYKDLNIFGPNGTRSPDLDWRQLPEPPKRSLLQRLFRRHNAD 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gprk1	NP_001036438.1	RGS_GRK2_GRK3	30..186	CDD:188701	43/160 (27%)
		PKc_like	185..531	CDD:304357	150/357 (42%)
		Pkinase	191..454	CDD:278497	125/266 (47%)
		PH_GRK2_subgroup	552..675	CDD:269946	1/1 (100%)
		PH	559..657	CDD:278594
grk5	NP_001017316.1	RGS	35..179	CDD:383028	40/150 (27%)
		PKc_like	183..495	CDD:389743	139/318 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1104340at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010