Protein Alignment Gprk1 and S6k

DIOPT Version :10

• Sequence 1: NP_001036438.1
• Gene: Gprk1 / 3355013
• FlyBaseID: FBgn0260798
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_308496.5
• Gene: S6k / 1269844
• VectorBaseID: AGAMI1_009257
• Length: 561
• Species: Anopheles gambiae
• Alignment Length: 342
• Identity: 124/342 - (36%)
• Similarity: 188/342 - (54%)
• Gaps: 32/342 - (9%)

  Fly   184 IQLTMNDFSVHRIIGRGGFGEVYGCRK---ADTGKMYAMKCLDKKRIKMKQGEMLALN-ERNMLQ 244
            |:|...||.:.:::|:||:|:|:..||   ||....:|||.|.|..|...|.:..... |||:|:
Mosquito    60 IKLGPQDFELKKVLGKGGYGKVFQVRKTTGADANSYFAMKVLKKASIVRNQKDTAHTRAERNILE 124

  Fly   245 AVSTGIDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGIFSEDEMKFYAAEVILGLEHM 309
            ||..    ||||.:.|||.|..||..||:.::||:|..||.:.|||.||...||..|:||.|||:
Mosquito   125 AVRH----PFIVELVYAFQTGGKLYLILEYLSGGELFMHLEREGIFLEDTACFYLCEIILALEHL 185

  Fly   310 HKRCIVYRDLKPANILLDENGHIRISDLGLACDFSKK--KPHASVGTHGYMAPEVLSKGTSYDSC 372
            |...|:||||||.|:|||..||::::|.||..:..::  ..|...||..|||||:|:: :.:...
Mosquito   186 HNLGIIYRDLKPENVLLDAKGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTR-SGHGKA 249

  Fly   373 ADWFSFGCMLYKLLKGHSPF---RQHKTKDKLEIDKMTLTMNVELPESFSLELKNLLEMLLQRDV 434
            .||:|.|.:::.:|.|..||   .:.||.|.:..||:      .:|...:.:.::|:..|::|.|
Mosquito   250 VDWWSLGALMFDMLTGMPPFCADNRKKTVDAILKDKL------NIPGYLTPDSRDLIRRLMKRQV 308

  Fly   435 SKRLGCMGNGADEVKMHNFFCGIDWHQVYIQKYTPPLVPPRGEVNAADAFDIGSFDEEDTKGIKL 499
            |:|||........|:.|.||..::|..|..::..||:.|.     .|...|:..||.:.||.|.:
Mosquito   309 SQRLGSGPTDGQAVRAHPFFKNVNWDDVVKRRLDPPIKPV-----LASEDDVSQFDTKFTKEIPV 368

  Fly   500 NDADQDLYKMFSLTISE 516
            :..|:       .|:||
Mosquito   369 DSPDE-------TTLSE 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gprk1	NP_001036438.1	RGS_GRK2_GRK3	30..186	CDD:188701	1/1 (100%)
		Protein Kinases, catalytic domain	185..531	CDD:473864	123/341 (36%)
		PH_GRK2_subgroup	552..675	CDD:269946
S6k	XP_308496.5	None