DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17683 and Narf

DIOPT Version :9

Sequence 1:	NP_001036428.1	Gene:	CG17683 / 3355011	FlyBaseID:	FBgn0262115	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_080548.3	Gene:	Narf / 67608	MGIID:	1914858	Length:	462	Species:	Mus musculus

Alignment Length:	460	Identity:	184/460 - (40%)
Similarity:	275/460 - (59%)	Gaps:	26/460 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 RSKTGAKIKIKGDG---------CFEESESGNL-KLNKVDISLQDCLACSGCITSAEEVLITQQS 87
            :|||..:..:..||         ..|..|.|.. ||....|.|.|||||..|:|..|.|.::|||
Mouse    14 KSKTDDQENVSSDGAQPSDGASPAKESEEKGEFHKLADAKIFLSDCLACDSCVTVEEGVQLSQQS 78

  Fly    88 REELLKVLQENSKNKASEDWDNVRTIVFTLATQPILSLAYRYQIGVEDAARHLNGYFRSLGADYV 152
            .::.|.||..|.:...|:.    |.:|.::..|.:...|.::.:.|.||:|.|.|:.:|||..||
Mouse    79 AKDFLHVLNLNKRCDTSKH----RVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKSLGVHYV 139

  Fly   153 LSTKVADDIALLECRQEFVDRY----RENENLTMLSSSCPGWVCYAEKTHGNFLLPYVSTTRSPQ 213
            ..|.:|.|.::||.::|||.||    .|...|.||:|:|||||.|||:..|..::||:.|.:|||
Mouse   140 FDTTIAADFSILESQKEFVRRYHQHSEEQRELPMLTSACPGWVRYAERVLGRPIIPYLCTAKSPQ 204

  Fly   214 QIMGVLVKQILADKMNVPASRIYHVTVMPCYDKKLEASREDFFSKANNSRDVDCVITSVEVEQLL 278
            |:||.|||...|.:.|:...:|:||.|.|||||||||.||...:..|.:|..|||:||.|:.|::
Mouse   205 QVMGSLVKDYFARQQNLSPEKIFHVVVAPCYDKKLEALREGLSTTLNGARGTDCVLTSGEIAQIM 269

  Fly   279 SEAQQPLSQYDLLDLDWPWSNVRPEFMVWAHEKTLSGGYAEHIFKYAAKHIFNEDLKTELEFKQL 343
            .  |..||..|:. :|..:.::: |..|..|:...|.|:..|:|::|||.:|.|.:: |:.::.|
Mouse   270 E--QSDLSVKDIA-VDTLFGDMK-EVAVQRHDGVSSDGHLAHVFRHAAKELFGEHVE-EITYRAL 329

  Fly   344 KNRDFREIILKQNGKTVLKFAIANGFRNIQNLVQKLKREKVSNYHFVEVMACPSGCINGGAQIRP 408
            :|:||.|:.|::||:.:|:||.|.|||||||::||||:.|:. ||||||:|||.||:||..|.:.
Mouse   330 RNKDFHEVTLEKNGEVLLRFAAAYGFRNIQNMIQKLKKGKLP-YHFVEVLACPRGCLNGRGQAQT 393

  Fly   409 TTGQHVRELTRKLEELYQNLPRSEPENSL-TKHIYNDFLDGFQSDKSYDVLHTRYHDVVSELSIS 472
            ..|...|.|.:::|.:|..:|...||:|. .:.:|.::|:|.:|.|..:||||.|.. :...:..
Mouse   394 EDGHTDRALLQQMEGIYSGIPVRPPESSTHVQELYQEWLEGTESPKVQEVLHTSYQS-LEPCTDG 457

  Fly   473 LNINW 477
            |:|.|
Mouse   458 LDIKW 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17683	NP_001036428.1	Nar1	29..464	CDD:226972	181/445 (41%)
		Fe_hyd_lg_C	111..406	CDD:280978	132/298 (44%)
		Fe_hyd_SSU	419..465	CDD:214899	16/46 (35%)
Narf	NP_080548.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43		6/28 (21%)
		Nar1	49..449	CDD:226972	171/409 (42%)
		Fe_hyd_lg_C	98..390	CDD:280978	132/297 (44%)
		Fe_hyd_SSU	404..452	CDD:214899	16/48 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832324
Domainoid	1	1.000	296	1.000	Domainoid score	I1468
eggNOG	1	0.900	-	-		E1_COG4624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54208
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002027
OrthoInspector	1	1.000	-	-		otm43884
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11615
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1333
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.810