DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17683 and Narf

DIOPT Version :9

Sequence 1:	NP_001036428.1	Gene:	CG17683 / 3355011	FlyBaseID:	FBgn0262115	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001034296.1	Gene:	Narf / 360681	RGDID:	1310894	Length:	456	Species:	Rattus norvegicus

Alignment Length:	454	Identity:	180/454 - (39%)
Similarity:	271/454 - (59%)	Gaps:	20/454 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 RSKTGAKIKIKGD---GCFEESESGNL-KLNKVDISLQDCLACSGCITSAEEVLITQQSREELLK 93
            :|||..:..:..|   ...|..|.|.. ||....|.|.|||||..|:|..|.|.::|||.::...
  Rat    14 KSKTDDQENVSVDVPSPAQENEEKGEFHKLADAKIFLSDCLACDSCVTVEEGVQLSQQSAKDFFH 78

  Fly    94 VLQENSKNKASEDWDNVRTIVFTLATQPILSLAYRYQIGVEDAARHLNGYFRSLGADYVLSTKVA 158
            ||..|.:...|:.    :.:|.::..|.:...|.::.:.|.||:|.|.|:.:|||..||..|.:|
  Rat    79 VLNLNKRCDTSKH----KVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKSLGVHYVFDTTIA 139

  Fly   159 DDIALLECRQEFVDRY----RENENLTMLSSSCPGWVCYAEKTHGNFLLPYVSTTRSPQQIMGVL 219
            .|.::||.::|||.||    .|...|.||:|:|||||.|||:..|..::||:.|.:||||:||.|
  Rat   140 ADFSILESQKEFVRRYHQHSEEQRELPMLTSACPGWVRYAERVLGRPIIPYLCTAKSPQQVMGSL 204

  Fly   220 VKQILADKMNVPASRIYHVTVMPCYDKKLEASREDFFSKANNSRDVDCVITSVEVEQLLSEAQQP 284
            ||...|.:.::...:|:|:.|.|||||||||.||......|.:|..|||:||.|:.|::.  |..
  Rat   205 VKDYFARQQSLAPEKIFHIVVAPCYDKKLEALREGLSPTLNGARGTDCVLTSGEIAQIME--QSD 267

  Fly   285 LSQYDLLDLDWPWSNVRPEFMVWAHEKTLSGGYAEHIFKYAAKHIFNEDLKTELEFKQLKNRDFR 349
            ||..|:. :|..:.:|: |..|..|:...|.|:..|:|::|||.:|.|.:: |:.::.|:|:||.
  Rat   268 LSVKDIA-VDTLFGDVK-EMAVRRHDGVSSDGHLAHVFRHAAKELFGEHVE-EITYRALRNKDFH 329

  Fly   350 EIILKQNGKTVLKFAIANGFRNIQNLVQKLKREKVSNYHFVEVMACPSGCINGGAQIRPTTGQHV 414
            |:.|::||:.:|:||.|.|||||||::.|||:.|.. ||||||:|||.||:||..|.:...|...
  Rat   330 EVTLEKNGEVLLRFAAAYGFRNIQNMIMKLKKGKFP-YHFVEVLACPRGCLNGRGQAQTEDGHTD 393

  Fly   415 RELTRKLEELYQNLPRSEPENSL-TKHIYNDFLDGFQSDKSYDVLHTRYHDVVSELSISLNINW 477
            |.|.:::|.:|..:|...||:|. .:.:|.::|:|.:|.|..:||||.|.. :...:.||:|.|
  Rat   394 RALLQQMEGIYSGIPVWPPESSTHVQELYQEWLEGTESPKVQEVLHTSYQS-LEPCTDSLDIKW 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17683	NP_001036428.1	Nar1	29..464	CDD:226972	176/439 (40%)
		Fe_hyd_lg_C	111..406	CDD:280978	129/298 (43%)
		Fe_hyd_SSU	419..465	CDD:214899	16/46 (35%)
Narf	NP_001034296.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	12..36		5/21 (24%)
		Nar1	43..443	CDD:226972	167/409 (41%)
		Fe_hyd_lg_C	92..384	CDD:280978	129/297 (43%)
		Fe_hyd_SSU	398..446	CDD:214899	16/48 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335979
Domainoid	1	1.000	297	1.000	Domainoid score	I1407
eggNOG	1	0.900	-	-		E1_COG4624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54208
OrthoDB	1	1.010	-	-		D370258at33208
OrthoFinder	1	1.000	-	-		FOG0002027
OrthoInspector	1	1.000	-	-		otm45972
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11615
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1333
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.860