DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17683 and oxy-4

DIOPT Version :9

Sequence 1:	NP_001036428.1	Gene:	CG17683 / 3355011	FlyBaseID:	FBgn0262115	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_498092.4	Gene:	oxy-4 / 175702	WormBaseID:	WBGene00021902	Length:	457	Species:	Caenorhabditis elegans

Alignment Length:	493	Identity:	165/493 - (33%)
Similarity:	258/493 - (52%)	Gaps:	56/493 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SRLSRALQLTDIDDFITPSQICIKPVQ---IDKARSKTGAKIKIKGDGCFEESESGNLKLNKVDI 63
            |..|..::|:::.|||.|:..||.|::   ::|.:.::...|:.|.....|.|::...|  .|.|
Worm     4 SGFSGVVRLSNVSDFIAPNLDCIIPLETRTVEKKKEESQVNIRTKKPKDKESSKTEEKK--SVKI 66

  Fly    64 SLQDCLACSGCITSAEEVLITQQSREELLKVLQENSKNKASEDWDNVRTIVFTLATQPILSLAYR 128
            ||.|||||||||||||.||:.:||...:.:.:|            |.:..|.|::.|.|.|:|.:
Worm    67 SLADCLACSGCITSAETVLVEEQSFGRVYEGIQ------------NSKLSVVTVSPQAITSIAVK 119

  Fly   129 YQIGVEDAARHLNGYFRSLGADYVLSTKVADDIA--LLECRQEFVDRYRE-----NENLTMLSSS 186
            ......:.|:.:..:||.||..||:.:..|...|  |:         |.|     :.:..:|||:
Worm   120 IGKSTNEVAKIIASFFRRLGVKYVIDSSFARKFAHSLI---------YEELSTTPSTSRPLLSSA 175

  Fly   187 CPGWVCYAEKTHGNFLLPYVSTTRSPQQIMGVLVKQILADKMNVPASRIYHVTVMPCYDKKLEAS 251
            |||:||||||:||..|:|.:|..||||.|.|.::|..||.:..:....::|..||||:|||||||
Worm   176 CPGFVCYAEKSHGELLIPKISKIRSPQAISGAIIKGFLAKREGLSPCDVFHAAVMPCFDKKLEAS 240

  Fly   252 REDFFSKANNSRDVDCVITSVE-VEQLLSEAQQPLSQYDLLDLDWPWSNVRPEFMVWAHEKTLSG 315
            ||.|.....:.|:.||||::.| :|:::..........:....:..|.:...:..|...:...||
Worm   241 REQFKVDGTDVRETDCVISTAELLEEIIKLENDEAGDVENRSEEEQWLSALSKGSVIGDDGGASG 305

  Fly   316 GYAEHIFKYAAKHIFNEDLKTE-----LEFKQLKNRDFREIILKQNGKTVLKFAIANGFRNIQNL 375
            |||:.|.:         |...|     ::..:|....|...:..:.|:.:|:.|...||||:|||
Worm   306 GYADRIVR---------DFVLENGGGIVKTSKLNKNMFSTTVESEAGEILLRVAKVYGFRNVQNL 361

  Fly   376 VQKLKREKVSNYHFVEVMACPSGCINGGAQIRPTTGQHVRELTRKLEELYQNLPRSEPENSLTKH 440
            |:|:|.:| ....:||:||||.||.|||.|||..|.....|...|:|.||::|||.:.|.:..|
Worm   362 VRKMKTKK-EKTDYVEIMACPGGCANGGGQIRYETMDEREEKLIKVEALYEDLPRQDDEETWIK- 424

  Fly   441 IYNDFLDGFQSDKSY-DVLHTRYHDVVSELSISLNINW 477
            :..::   .:.||:| ::|.|.|..|  |.:::..:.|
Worm   425 VREEW---EKLDKNYRNLLFTDYRPV--ETNVAQVLKW 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17683	NP_001036428.1	Nar1	29..464	CDD:226972	152/448 (34%)
		Fe_hyd_lg_C	111..406	CDD:280978	103/307 (34%)
		Fe_hyd_SSU	419..465	CDD:214899	15/46 (33%)
oxy-4	NP_498092.4	Nar1	50..445	CDD:226972	148/431 (34%)
oxy-4	NP_498092.4	Fe_hyd_lg_C	102..391	CDD:280978	103/307 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	174	1.000	Domainoid score	I2197
eggNOG	1	0.900	-	-		E1_COG4624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I2003
Isobase	1	0.950	-	0	Normalized mean entropy	S1691
OMA	1	1.010	-	-		QHG54208
OrthoDB	1	1.010	-	-		D370258at33208
OrthoFinder	1	1.000	-	-		FOG0002027
OrthoInspector	1	1.000	-	-		oto18868
orthoMCL	1	0.900	-	-		OOG6_101268
Panther	1	1.100	-	-	LDO	PTHR11615
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R794
SonicParanoid	1	1.000	-	-		X1333
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.860