DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17168 and slc4a1ap

DIOPT Version :9

Sequence 1:	NP_001015254.1	Gene:	CG17168 / 3354996	FlyBaseID:	FBgn0039943	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_002938467.3	Gene:	slc4a1ap / 100494917	XenbaseID:	XB-GENE-478512	Length:	1037	Species:	Xenopus tropicalis

Alignment Length:	454	Identity:	110/454 - (24%)
Similarity:	167/454 - (36%)	Gaps:	90/454 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TGHEGDTKMSDRNLSKTKKIKQRATADSSSSSDSSNESKKSNHS---------SLSPNRKQR--- 68
            ||...:|:...|........:.:...||.|...:.::|:..|.|         |..||..|.
Frog   106 TGTSAETQRDSRPTQGPNDSQSQGPNDSQSQGPNDSQSQGPNDSQSQGPNDSQSQGPNHAQSEGS 170

  Fly    69 --TAGKRQRDSSQSQEKRHKQLTHPSEDVHEQRSKWDSPERSNSHRNSTRQRRNTRSRSRERSER 131
              |..|...| ||.|...|.|...|:   |.|....:..:...||....:...||:||....::.
Frog   171 HVTQCKGPND-SQCQGPNHAQCQGPN---HAQCQGPNHAQSEGSHVTQCQGPNNTQSRGANNAQS 231

  Fly   132 ERDRDCERNKERDYNM-----------QSSKERWQRSPALRHRSRSSERKNRERDRQRRPT---- 181
            :......:..:...:.           |||.  |.......:.|.:|..|.....|....|
Frog   232 QGSHVTPKGPDNSQSQGPHVTQSHGEGQSSS--WTNEDEHSNASGASTPKESSSPRGISSTGPDS 294

  Fly   182 -----ERRPVRR-------SQSPR----DRCHGGRDLDQRRQRNQRHNNSNKNEDDHYVWGKEV- 229
                 |::|..|       |::|.    ..|...||.......:.|...|.|         |.:
Frog   295 AGATPEKQPSPRPSYGEIASRTPSKDGGSGCSAPRDSPMEGPDDARTTESFK---------KPIF 350

  Fly   230 ------DEKVPAENDVPV--------------DKEKPNFGLSGALTEDTNKLNGVVVKYSEPPEA 274
                  .||.....|.||              ..|.|..| :..|..|..: ....:.|.|||.:
Frog   351 AARPSGTEKAAQPRDKPVVHSQPSAPTCSRTPSAETPTDG-NARLPSDAYR-TCPAIPYREPPWS 413

  Fly   275 RKPKRRWRLYPFKGETALPTLHIHRQSCFLVGRDRKVVDLAVDHPSCSKQHAALQYRLVPFERED 339
            ..|:..:.|...||.:.:.|.::...|..:.|| .....::::|||.|:.||.||||.|.....|
Frog   414 GLPEALYCLEILKGGSIVSTKNLGNVSWTVFGR-LPSCHVSLEHPSVSRYHAVLQYRHVQGSGPD 477

  Fly   340 GSHGKRVRLYLIDLDSANGTFLNNKKIDARKYYELIEKDVIKFGFSSREYVLLHENSKEDQEDD 403
            ...|    .|:.||.|.:|||||.::|.|:.|..:....|:|||.|:|.::|  :..:||||::
Frog   478 EEPG----FYVYDLGSTHGTFLNKQRIQAKTYCRIRVGHVLKFGGSTRLFIL--QGPEEDQEEE 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17168	NP_001015254.1	FHA	280..395	CDD:238017	39/114 (34%)
CG17168	NP_001015254.1	FHA	<294..411	CDD:224630	40/110 (36%)
slc4a1ap	XP_002938467.3	PHA03307	9..>420	CDD:223039	67/330 (20%)
		ser_rich_anae_1	<121..>291	CDD:411418	35/175 (20%)
		FHA	419..526	CDD:238017	39/113 (35%)
		DSRM_Kanadaptin	613..695	CDD:380685
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D955935at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920