DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment su(f) and CSTF77

DIOPT Version :9

Sequence 1:	NP_001015241.3	Gene:	su(f) / 3354994	FlyBaseID:	FBgn0003559	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_173218.2	Gene:	CSTF77 / 838354	AraportID:	AT1G17760	Length:	734	Species:	Arabidopsis thaliana

Alignment Length:	780	Identity:	238/780 - (30%)
Similarity:	384/780 - (49%)	Gaps:	130/780 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 YDIESWSVMIREAQTRPIHEVRSLYESLVNVFPTTARYWKLYIEMEMRSRYYERVEKLFQRCLVK 95
            |.:|....:.:.|...||.:...:||.|::::||:||:||.|:|.:|.....:..:::|.|||:.
plant     5 YIVEEAEALAKRALHSPIAQATPIYEQLLSLYPTSARFWKQYVEAQMAVNNDDATKQIFSRCLLT 69

  Fly    96 ILNIDLWKLYLTYVKET--KSGLSTHKEKMAQAYDFALEKIGMDLHSFSIWQDYIYFLRGVEAVG 158
            .|.:.||:.|:.::::.  |.| :..:|:..:|::|.|..||.|:.|..||.:||.||:.:.|:.
plant    70 CLQVPLWQCYIRFIRKVYDKKG-AEGQEETTKAFEFMLNYIGTDIASGPIWTEYIAFLKSLPALN 133

  Fly   159 NYAENQKITAVRRVYQKAVVTPIVGIEQLWKDYIAFEQNINPIISEKMSLERSKDYMNARRVAKE 223
            ...:..:.||:|:||.:|::||...:|||||||..||..:|..:::.:..|....:.:||.|.:|
plant   134 LNEDLHRKTALRKVYHRAILTPTHHVEQLWKDYENFENTVNRQLAKGLVNEYQPKFNSARAVYRE 198

  Fly   224 LEYHTKGLNRNLPAVPPTLTKEEVKQVELWKRFITYEKSNPLRTEDTALVTRRVMFATEQCLLVL 288
            .:.:.:.::.|:.|||||.|.:|..|...||:|:::||.||.|. |||..|:|:::|.||||:.|
plant   199 RKKYIEEIDWNMLAVPPTGTSKEETQWVAWKKFLSFEKGNPQRI-DTASSTKRIIYAYEQCLMCL 262

  Fly   289 THHPAVWHQASQFLDTSARVLTEKGVRTSVENISPILCVPVVNQIEWVMAFAWWWAKDVQAAKIF 353
            .|:|.||:.                                         :|.|..|...
plant   263 YHYPDVWYD-----------------------------------------YAEWHVKSGS----- 281

  Fly   354 ADECANILERSINGVLNRNALLYFAYADFEEGRLKYEKVHTMYNKLLQLPDIDPTLVYVQYMKFA 418
            .|....:.:|::..:.: :.:|.:|:|:.||.|...:....:|..:|...  ..:|.::||::|.
plant   282 TDAAIKVFQRALKAIPD-SEMLKYAFAEMEESRGAIQSAKKLYENILGAS--TNSLAHIQYLRFL 343

  Fly   419 RRAEGIKSARSIFKKAREDVRSRYHIFVAAALMEYYCSKDKEIAFRIFELGLKRFGGSPEYVMCY 483
            |||||:::||..|..||:.....||:::|.|.|.:...|:.::|..|||.|||.:...|.|::.|
plant   344 RRAEGVEAARKYFLDARKSPSCTYHVYIAFATMAFCIDKEPKVAHNIFEEGLKLYMSEPVYILKY 408

  Fly   484 IDYLSHLNEDNNTRVLFERVLSSGGLSPHKSVEVWNRFLEFESNIGDLSSIVKVERRRSAVFENL 548
            .|:|:.||:|.|.|.||||.||:  |....|.|||.||::||...|||:||:|||:|.......
plant   409 ADFLTRLNDDRNIRALFERALST--LPVEDSAEVWKRFIQFEQTYGDLASILKVEQRMKEALSG- 470

  Fly   549 KEYEGKETAQ-----LVDRYKFLDLYPCTSTELKSIGYAENVGIILNKVGGGAQSQNT----GEV 604
            |..||....:     :|.||.::||:||||.:|..:...|.:...|||..|.....:.    |.|
plant   471 KGEEGSSPPESSLQDVVSRYSYMDLWPCTSNDLDHLARQELLVKNLNKKAGKTNLPHVPAAIGSV 535

  Fly   605 ETDSEATPPLPRPDFSQMI---PFKPRPCAHPGAHPL---AGGVFPQ------------------ 645
            .:.|:..    .||.|||:   |.|....| ..|:|:   |...||.
plant   536 ASSSKVV----YPDTSQMVVQDPTKKSEFA-SSANPVAASASNTFPSTVTATATHGSASTFDEIP 595

  Fly   646 ---PPALAALCATLPPPNSFRGPFVSVELLFDIFMRLNLPDS-------APQPNGDNELSPKIFD 700
               ||||.|..|.||..:   ||..:|:::..|.::.:.|..       |.:.|..::..|
plant   596 KTTPPALVAFLANLPIVD---GPTPNVDVVLSICLQSDFPTGQTVKQSFAAKGNPPSQNDP---- 653

  Fly   701 LAKSVHWIVDTSTYTGVQHSVTAVPPRRRRLLPGGD-DSDDELQTAV----PPSHDIYRLRQLKR 760
                          :|....|:...||.||.....| |..:|..||.    |...|::||||:::
plant   654 --------------SGPTRGVSQRLPRDRRATKRKDSDRQEEDDTATVQSQPLPTDVFRLRQMRK 704

Fly 761 760
plant 705 704

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(f)	NP_001015241.3	RNA14	19..550	CDD:227438	171/520 (33%)
		HAT	48..78	CDD:214642	12/29 (41%)
		Suf	408..682	CDD:283497	107/309 (35%)
CSTF77	NP_173218.2	RNA14	28..494	CDD:227438	172/519 (33%)
		TPR repeat	266..294	CDD:276809	8/73 (11%)
		TPR repeat	299..328	CDD:276809	7/28 (25%)
		Suf	333..632	CDD:399092	107/309 (35%)
		TPR repeat	333..361	CDD:276809	13/27 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	190	1.000	Domainoid score	I953
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1014
Inparanoid	1	1.050	351	1.000	Inparanoid score	I614
OMA	1	1.010	-	-		QHG57539
OrthoDB	1	1.010	-	-		D331411at2759
OrthoFinder	1	1.000	-	-		FOG0001614
OrthoInspector	1	1.000	-	-		oto3696
orthoMCL	1	0.900	-	-		OOG6_102277
Panther	1	1.100	-	-	LDO	PTHR19980
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1181
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.980