DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment su(f) and LOC100496477

DIOPT Version :9

Sequence 1:	NP_001015241.3	Gene:	su(f) / 3354994	FlyBaseID:	FBgn0003559	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	XP_031756597.1	Gene:	LOC100496477 / 100496477	-ID:	-	Length:	770	Species:	Xenopus tropicalis

Alignment Length:	764	Identity:	415/764 - (54%)
Similarity:	539/764 - (70%)	Gaps:	89/764 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EWGMERLVRAQQVVELRPYDIESWSVMIREAQTRPIHEVRSLYESLVNVFPTTARYWKLYIEMEM 77
            |:..|::.:|::.:|..|||:::||::|||||.:||.:.|..||.||..||::.|:||||||.|:
Frog    78 EYVPEKVKKAEKKLEDNPYDLDAWSILIREAQNQPIDKARKTYEXLVAQFPSSGRFWKLYIEAEV 142

  Fly    78 RSRYYERVEKLFQRCLVKILNIDLWKLYLTYVKETKSGLSTHKEKMAQAYDFALEKIGMDLHSFS 142
            :::..::|||||||||:|:|:|||||.|::||:|||..|.::||||||||||||:||||::.|:.
Frog   143 KAKNDDKVEKLFQRCLMKVLHIDLWKCYVSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQ 207

  Fly   143 IWQDYIYFLRGVEAVGNYAENQKITAVRRVYQKAVVTPIVGIEQLWKDYIAFEQNINPIISEKMS 207
            ||.|||.||:||||||:|||||:|||||||||:..|.|::.|||||:||..:|:.||..:::||.
Frog   208 IWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMI 272

  Fly   208 LERSKDYMNARRVAKELEYHTKGLNRNLPAVPPTLTKEEVKQVELWKRFITYEKSNPLRTEDTAL 272
            .:||:|||||||||||.|...|||:||.|:|||..|.:|.:|||:.|::|.:||||||||||..|
Frog   273 EDRSRDYMNARRVAKEYETVMKGLDRNAPSVPPQNTPQEAQQVEMGKKYIQWEKSNPLRTEDQTL 337

  Fly   273 VTRRVMFATEQCLLVLTHHPAVWHQASQFLDTSARVLTEKGVRTSVENISPILCVPVVNQIEWVM 337
            :|:|||||.|||||||.|||.:|::|.|:|:.|:::|.|||
Frog   338 ITKRVMFAYEQCLLVLGHHPDIWYEAGQYLEQSSKLLAEKG------------------------ 378

  Fly   338 AFAWWWAKDVQAAKIFADECANILERSINGVLNRNALLYFAYADFEEGRLKYEKVHTMYNKLLQL 402
                    |:..||:|:||.|||.||:|:.:|.:|.||||||||:||.|:||||.|::||:||.:
Frog   379 --------DMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKTHSIYNRLLAI 435

  Fly   403 PDIDPTLVYVQYMKFARRAEGIKSARSIFKKAREDVRSRYHIFVAAALMEYYCSKDKEIAFRIFE 467
            .||||||||:|||:||||||||||.|.||||||||.|:|:|::|.|||||||||||..:||:|||
Frog   436 EDIDPTLVYIQYMEFARRAEGIKSGRMIFKKAREDPRTRHHVYVTAALMEYYCSKDTSVAFKIFE 500

  Fly   468 LGLKRFGGSPEYVMCYIDYLSHLNEDNNTRVLFERVLSSGGLSPHKSVEVWNRFLEFESNIGDLS 532
            ||||::|..||||:.||||||||||||||||||||||:||.|.|.||.|:|.|||.||||||||:
Frog   501 LGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLA 565

  Fly   533 SIVKVERRRSAVFENLKEYEGKETAQLVDRYKFLDLYPCTSTELKSIGY-----AENVGIILNKV 592
            ||:|||:||...|:  :||||||||.|||||||:|||||:::|||::||     |:...:|.:.|
Frog   566 SILKVEKRRYTAFK--EEYEGKETALLVDRYKFMDLYPCSTSELKALGYKDVSRAKLAALIPDPV 628

  Fly   593 GGGAQSQNTGEVETDSEATPPLPRPDFSQMIPFKPRPCAHPGAHPLAGGVFPQPPALAALCATLP 657
                            :..|..|:||.||||||:||..|.||.||:.|||||.|||...|...||
Frog   629 ----------------DRKPEYPKPDTSQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVILMKLLP 677

  Fly   658 PPNSFRGPFVSVELLFDIFMRLNLPDSAPQPNGDNELSPKIFDLAKSVHWIVDTSTYTGVQHSVT 722
            ||..|:||||.|:.:.:|..|..|||:                :.::|..|      ||.|..:.
Frog   678 PPICFQGPFVQVDEIMEILWRCKLPDT----------------VEEAVRII------TGSQAEMN 720

  Fly   723 AV---PPRRRRLL------PGGDDSDDELQ--TAVPPSHDIYRLRQLKR 760
            ..   |...:.||      | .:|||||.:  :.|||.|||||.||.||
Frog   721 MEGNGPVEGKTLLNKSVKRP-NEDSDDEEEKGSVVPPVHDIYRTRQQKR 768

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(f)	NP_001015241.3	RNA14	19..550	CDD:227438	318/530 (60%)
		HAT	48..78	CDD:214642	16/29 (55%)
		Suf	408..682	CDD:283497	170/278 (61%)
LOC100496477	XP_031756597.1	RNA14	66..598	CDD:227438	335/553 (61%)
LOC100496477	XP_031756597.1	Suf	441..702	CDD:399092	170/278 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217087at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010