DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment su(f) and XB5939409

DIOPT Version :9

Sequence 1:	NP_001015241.3	Gene:	su(f) / 3354994	FlyBaseID:	FBgn0003559	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	XP_031756596.1	Gene:	XB5939409 / 100493745	XenbaseID:	XB-GENE-5939410	Length:	703	Species:	Xenopus tropicalis

Alignment Length:	801	Identity:	317/801 - (39%)
Similarity:	428/801 - (53%)	Gaps:	246/801 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EWGMERLVRAQQVVELRPYDIESWSVMIREAQTRPIHEVRSLYESLVNVFPTTARYWKLYIEMEM 77
            |:..|::.:|::.:|..|||:::||::|||||.:||.:.|..||.||..||::.|:||||||.|:
Frog    94 EYVPEKVKKAEKKLEDNPYDLDAWSILIREAQNQPIDKARKTYERLVAQFPSSGRFWKLYIEAEV 158

  Fly    78 RSRYYERVEKLFQRCLVKILNIDLWKLYLTYVKETKSGLSTHKEKMAQAYDFALEKIGMDLHSFS 142
            :::.|::|||||||||:|:|:|||||.|::||:|||..|.::||||||||||||:||||::.|:.
Frog   159 KAKNYDKVEKLFQRCLMKVLHIDLWKCYVSYVRETKRKLPSYKEKMAQAYDFALDKIGMEIMSYP 223

  Fly   143 IWQDYIYFLRGVEAVGNYAENQKITAVRRVYQKAVVTPIVGIEQLWKDYIAFEQNINPIISEKMS 207
            ||.|||..:..| .|.::.                          |             :|..:|
Frog   224 IWVDYINAMIAV-CVASFT--------------------------W-------------VSSTLS 248

  Fly   208 LERSKDYMNARRVAKELEYHTKGLNRNLPAVPPTLTKEEVKQVELWKRFITYEKSNPLRTEDTAL 272
            :..|.|
Frog   249 VCASLD----------------------------------------------------------- 254

  Fly   273 VTRRVMFATEQCLLVLTHHPAVWHQASQFLDTSARVLTEKGVRTSVENISPILCVPVVNQIEWVM 337
                                          .:|.:||
Frog   255 ------------------------------GSSFKVL---------------------------- 261

  Fly   338 AFAWWWAKDVQAAKIFADECANILERSINGVLNRNALLYFAYADFEEGRLKYEKVHTMYNKLLQL 402
              .::.::|:..||:|:||.|||.||:|:.:|.:|.||||||||:||.|:||||.|::||:||.:
Frog   262 --HFFLSQDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKTHSIYNRLLAI 324

  Fly   403 PDIDPTLVYVQYMKFARRAEGIKSARSIFKKAREDVRSRYHIFVAAALMEYYCSKDKEIAFRIFE 467
            .||||||||:||||||||||||||.|.||||||||.|:|:|::|.|||||||.|||..:||:|||
Frog   325 EDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDPRTRHHVYVTAALMEYYFSKDTSVAFKIFE 389

  Fly   468 LGLKRFGGSPEYVMCYIDYLSHLNEDNNTRVLFERVL---------------------------- 504
            ||||::|..||||:.||||||||||||||||||||.:
Frog   390 LGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERKIRVSLNINFVYGRPVIETAVRDDSLKSRT 454

  Fly   505 ---SSGGLSPHKSVEVWNRFLEFESNIGDLSSIVKVERRRSAVFENLKEYEGKETAQLVDRYKFL 566
               ::..|..:..:|:|.|||.||||||||:||:|||:||...|:  :||||||||.|||||||:
Frog   455 FPCAALSLLLYTVIEIWARFLAFESNIGDLASILKVEKRRYTAFK--EEYEGKETALLVDRYKFM 517

  Fly   567 DLYPCTSTELKSIGY-----AENVGIILNKVGGGAQSQNTGEVETDSEATPPLPRPDFSQMIPFK 626
            |||||:::|||::||     |:...:|.:.|...:.:.:   ::.|.:..|..|:||.||||||:
Frog   518 DLYPCSTSELKALGYKDVSRAKLAALIPDPVIAPSIAPS---LKDDVDRKPEYPKPDTSQMIPFQ 579

  Fly   627 PRPCAHPGAHPLAGGVFPQPPALAALCATLPPPNSFRGPFVSVELLFDIFMRLNLPDSAPQP--- 688
            ||..|.||.||:.|||||.|||...|...||||..|:||||.|:.:.:|..|..|||:..:.
Frog   580 PRHLAPPGLHPVPGGVFPVPPAAVILMKLLPPPICFQGPFVQVDEIMEILRRCKLPDTVEEAVRI 644

  Fly   689 ------------NGDNELSPKIFDLAKSVHWIVDTSTYTGVQHSVTAVPPRRRRLLPGGDDSDDE 741
                        ||..|::..   |.|||                       :|   ..:|||||
Frog   645 ITGSQAEMNMEGNGPVEVNTL---LNKSV-----------------------KR---PNEDSDDE 680

  Fly   742 LQ--TAVPPSHDIYRLRQLKR 760
            .:  :.|||.|||||.||.||
Frog   681 EEKGSVVPPVHDIYRTRQQKR 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(f)	NP_001015241.3	RNA14	19..550	CDD:227438	220/561 (39%)
		HAT	48..78	CDD:214642	16/29 (55%)
		Suf	408..682	CDD:283497	164/309 (53%)
XB5939409	XP_031756596.1	RNA14	86..518	CDD:227438	237/584 (41%)
		TPR repeat	113..142	CDD:276809	15/28 (54%)
		TPR repeat	147..174	CDD:276809	16/26 (62%)
		Suf	330..635	CDD:399092	164/309 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217087at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010