Protein Alignment zyd and ECM27

DIOPT Version :10

• Sequence 1: NP_001015261.3
• Gene: zyd / 3354992
• FlyBaseID: FBgn0265767
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_012640.4
• Gene: ECM27 / 853570
• SGDID: S000003867
• Length: 725
• Species: Saccharomyces cerevisiae
• Alignment Length: 733
• Identity: 116/733 - (15%)
• Similarity: 221/733 - (30%)
• Gaps: 287/733 - (39%)

  Fly    31 PRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKIC--------------AALNMS 81
            ||.|:.:.:.....:|..:...:..||.|.:...::..|.|..|.              .|.:.|
Yeast    10 PRLLYKDPKLSVTFIVPSLFHIIIAFVLLGICASDFLCPNVAHISDPNSLRSNGSLVSKTASHAS 74

  Fly    82 NDVA-GATFMAAATSAPELFVNVIG-------TFITEGDIGVGTIVGSAVFNILAVAACCGI--- 135
            :..| .|..::...|:|:||.|::.       |..|...:.:|.::|:           |||
Yeast    75 HTGALMAVLLSWCNSSPDLFSNLMSWATSTRETRSTSVSLSIGEVLGA-----------CGIILC 128

  Fly   136 ---GAGMTI---------PLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLA 188
               |:...|         .:....:.||.:.....:.::..|....:|.....|::..|||.||.
Yeast   129 IVEGSIFIIMSRTHIEISQIQKLSIMRDLLFSLAAMCVMSYVSLMNQVTVLNCLLMAFLYAFYLV 193

  Fly   189 VMYFDKTFQKCAKGGVKQARSRSRSSNCS---------------------IHTKNSNEKEPELVE 232
            |....|............|.:..|.::.|                     |....::..:|.|:.
Yeast   194 VKLTFKLNHSAETPDETAADTSLRENSVSPFLDDSLMASGLLPPIQPGFDISNSITHGIKPSLLS 258

  Fly   233 NRICQNMANIQLNGGLNKEQAK--------------------ATSTSGAGTTA---ISITTSTMT 274
            .....:..::..|..|.::.::                    :.:.:|..|:|   .|..|:..|
Yeast   259 AMDFNSFLSMLENSSLEEDDSRNEMAELNTLRSMTPGQHWSASATVAGEATSAGRPFSEPTNAFT 323

  Fly   275 TTLSTTHSAGGGGGAVGLCSGPGAIVQMAPL----DDAEAESHVAVAAADEG-----------RK 324
            ....:..:         :.|.|..   .||.    ||.|::..|.:.....|           ::
Yeast   324 EYRDSERA---------INSSPAV---FAPYRDNPDDEESQEQVLLETTTHGHFGAQEMRRFSKR 376

  Fly   325 EEGYSLLSYPKDKSCFAQ-------FTWLIIWPIHLLFRIAIPD--------------------- 361
            ..|:.:..:....|.|:|       |: :|..|..::|:::.|.
Yeast   377 SLGWIIKIFIPHLSNFSQKSISDAIFS-IITVPFFIIFKLSCPQPPSDILSYDPTLNRYSLTTLP 440

  Fly   362 ---------------C------------------------------------------------- 362
                           |
Yeast   441 IILLFIQSITAPFLLCSILSVLLTYHLGYLVYLFPLILAMALILLLTAFITKVNLHNKFTLSLDS 505

  Fly   363 -----KKAKNNKI------------FPLTFIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGIT 410
                 :|.:..|:            ..:..|..|:||..|:..:..|:.|....|.:..:::|:|
Yeast   506 SNILQEKLQKRKLLERLNTSIQIIFLAIGIINIIIWISLLANSLIEMMEIYQKILGLSKAILGLT 570

  Fly   411 FLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNT--------------FDILLCLGVPWLIKAV 461
            ..|.|.||.:.:|::          .:|....:.|              .....|||
Yeast   571 IFAWGNSVGDLISNI----------SMCRLYKTQTHYQDRVRLATKFFMISCASCLG-------- 617

  Fly   462 FFPIQPGQNYVAINS-AGLEYSAITLLSTLFLLYLTFSTNKFKLDKKV---GTACL--------V 514
                     .|.:|| .|:.:|.  |:|.||:  ..|:.|::...:||   .|:.|        :
Yeast   618 ---------GVMLNSMGGIGFSG--LVSMLFI--GAFNDNEWWFLRKVKLQETSQLDNTLNYKFI 669

  Fly   515 MYLVFMVFASLIELNVFF 532
            :..||::. .:|.|.:||
Yeast   670 VSCVFIIL-QIILLLLFF 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zyd	NP_001015261.3	2A1904	<29..527	CDD:273344	112/726 (15%)
ECM27	NP_012640.4	Na_Ca_ex	27..196	CDD:426387	35/179 (20%)
		PLN03151	<544..637	CDD:215604	23/121 (19%)