Protein Alignment zyd and slc24a6a

DIOPT Version :9

• Sequence 1: NP_001015261.3
• Gene: zyd / 3354992
• FlyBaseID: FBgn0265767
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: XP_009289475.1
• Gene: slc24a6a / 561209
• ZFINID: ZDB-GENE-100922-39
• Length: 639
• Species: Danio rerio
• Alignment Length: 565
• Identity: 214/565 - (37%)
• Similarity: 312/565 - (55%)
• Gaps: 78/565 - (13%)

  Fly    26 AIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNMSNDVAGATFM 90
            ||.:||:|:|::.||:.||::|||..::|:|.|||:|||.:|||::||||..|::|.||||||||
Zfish    88 AIHEFPQDIFTKGQRRHGAILLHVFCAVYMFYALAIVCDVFFVPSLEKICENLHLSEDVAGATFM 152

  Fly    91 AAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMTIPLDWWPLTRDSIAY 155
            ||.:||||||.::||.|||:||:||||||||||||||.:...|||.||.||.|.||||.||||.|
Zfish   153 AAGSSAPELFTSLIGVFITKGDLGVGTIVGSAVFNILVIIGVCGIFAGQTITLTWWPLFRDSIFY 217

  Fly   156 GVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTF------------QKCAKGGVKQAR 208
            .::|..||.:::||:|.|:|.:||:|:|.||:.:|.|:...            |.|....:::..
Zfish   218 ILSVLALILIIYDEKVIWWETIILISMYGVYILIMKFNSQIWGWVEQRFGIPGQPCLVSSLRRDV 282

  Fly   209 SRSRSS-NCS----IHTKNSN---EKEPELVENRICQ------NMANIQLNGGLNKEQAKATSTS 259
            |...:| :|.    :..|..|   :..|.::.:.:..      :.:...|...:....:..|..|
Zfish   283 SVGEASPHCDTSMILLKKGQNAGGQDSPVVMVDELMSLHPHQFSFSEASLRVMITPHFSPRTRLS 347

  Fly   260 GAGTTAISITTSTMTTTLSTTHSAGGGGGAVGLCSGPGA-------------------------- 298
            .||...|: ....:....|...|:|.|.|......|||.
Zfish   348 MAGRMLIT-ERQRLIRNRSPGDSSGSGAGDTPGQDGPGMEAVPWGLENGGALESETQPLEEPRRR 411

  Fly   299 -----------IVQMAPLDDAEAESHVAVAAADEGRKEEGYSLLSYPKDKSCFAQFTWLIIWPIH 352
                       |....|.||.|.|         |...||.:...:.|:.:  :.|..|:..||:.
Zfish   412 SQGGELERVADIEDTQPKDDEEDE---------EEADEEPFRPFTVPEGR--WEQAKWMFSWPLS 465

  Fly   353 LLFRIAIPDCKKAKNNKIFPLTFIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTS 417
            .|....:|:|...:..:.|.:||:...:||...||::.||:|||..||.|||.||||||||||||
Zfish   466 CLLYYTVPNCVLPRWERWFMVTFVASTLWIAVFSYLMVWMVTIISFTLDIPDVVMGITFLAAGTS 530

  Fly   418 VPEAVSSVIVAKRGHGSMGICNSIGSNTFDILLCLGVPWLIKAVFFPIQPGQNYVAINSAGLEYS 482
            ||:.::|:|||::|.|.|.:.||||||.|||||.||.||.::.:.  :..|.. |:|||.||.||
Zfish   531 VPDCMASLIVARQGMGDMAVSNSIGSNIFDILLGLGFPWALRTLV--VDYGST-VSINSKGLVYS 592

  Fly   483 AITLLSTLFLLYLTFSTNKFKLDKKVGTACLVMYLVFMVFASLIE 527
            .|.||:::||..|:...|.::||:::|...:.:|.:|::.:...|
Zfish   593 VILLLASVFLTVLSVHLNHWRLDRRLGLGLMFLYAIFLLCSICFE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zyd	NP_001015261.3	ECM27	46..522	CDD:223604	203/538 (38%)
		Na_Ca_ex	48..192	CDD:279963	88/143 (62%)
		Na_Ca_ex	370..525	CDD:279963	74/154 (48%)
slc24a6a	XP_009289475.1	Na_Ca_ex	<85..637	CDD:332332	213/563 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577438
Domainoid	1	1.000	187	1.000	Domainoid score	I3263
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	407	1.000	Inparanoid score	I1859
OMA	1	1.010	-	-		QHG50092
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	1	1.000	-	-		otm25347
orthoMCL	1	0.900	-	-		OOG6_103920
Panther	1	1.100	-	-	O	PTHR10846
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1463
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.810