Protein Alignment zyd and Slc24a1

DIOPT Version :9

• Sequence 1: NP_001015261.3
• Gene: zyd / 3354992
• FlyBaseID: FBgn0265767
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_659062.1
• Gene: Slc24a1 / 214111
• MGIID: 2384871
• Length: 1130
• Species: Mus musculus
• Alignment Length: 724
• Identity: 193/724 - (26%)
• Similarity: 297/724 - (41%)
• Gaps: 234/724 - (32%)

  Fly    29 DFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNMSNDVAGATFMAAA 93
            ::|.||||...|:.|.||||:...:|:|||||:|||||||||:..|...|.:|.||||||||||.
Mouse   406 EYPPDLFSVEDRRQGWVVLHIFGMMYVFVALAIVCDEYFVPALGVITHKLQISEDVAGATFMAAG 470

  Fly    94 TSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMTIPLDWWPLTRDSIAYGVT 158
            .||||||.::||.||:..::|:||||||||||||.|...|.:.:...:.|.||||.||...|.:.
Mouse   471 GSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPLFRDVSFYILD 535

  Fly   159 VAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTFQ----------------------KCAK 201
            :::||....|..:.|:|:|:|:..||:|:..|.::|..:                      |.::
Mouse   536 LSMLIVFFLDSFIAWWESLLLLLAYALYVFTMKWNKQIELWVKEQLSRRPVAKVMALGDLSKPSE 600

  Fly   202 GGVKQARSRSR------------SSNCSIH---------------------TKNSNEKEPEL-VE 232
            ..|::...:..            ||:.|:|                     .:.|.:|:..| .|
Mouse   601 DAVEENEQQDSKKLKLPSVLTRGSSSASLHNSIIRNTIYHLMLHSLDPLGEARPSKDKQESLNQE 665

  Fly   233 NRI----------------------------------------CQ-NMANIQLNGGLNKEQA-KA 255
            .|:                                        || ::...:..|.:..|:. |.
Mouse   666 ARVLSQTKAESSPDEDEPAELPAVTVTPAPAPDAKGDQEDDPGCQEDVDEAERRGEMTGEEGEKE 730

  Fly   256 TST-------------------------------------------------------------- 258
            |.|
Mouse   731 TETEGKKDEQEGETEAERKEDEQEEETEAEGKEQEGETEAEGKEDEQEGETEAEGKKDEQEGETE 795

  Fly   259 ---------------------------------------------------------SGAGTTAI 266
                                                                     .|.|.|..
Mouse   796 AEGKEEQEGETEAEGKEDEQEGETEAEGKEEQEGETEAESKEVEQERETEAEGKDKHEGQGETQP 860

  Fly   267 SITT------STMTTTLSTTHSAGGGGGAVGLCSGPGAIVQMAPLDDAEAESHVAVAAADEGRKE 325
            ..|.      .|.........:..|..||.|.....|...:....::.|.|........:|...|
Mouse   861 DDTEVKDGEGETEANAEDQCEATQGEKGADGGGESDGGDSEEEEDEEDEEEEEEEDEEEEEEENE 925

  Fly   326 EGYSLLSYPKDKSCFAQFTWLIIWPIHLLFRIAIPDCKKAKNNKIFPLTFIMCIVWIGSLSYVVA 390
            |..| |.:|..:.  .|..:|.:.||.....:.|||.::.::.|.|.:||:..|:||...||::.
Mouse   926 EPLS-LEWPDSRQ--KQAIYLFLLPIVFPLWLTIPDVRRQESRKFFVITFLGSIIWIAMFSYLMV 987

  Fly   391 WMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFDILLCLGVP 455
            |....:|:|:.|.:.:||:|.||||||:|:.::|||||::|.|.|.:.:|:|||.|||.:.|.||
Mouse   988 WWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVP 1052

  Fly   456 WLIKAVFFPIQPGQNYVAINSAGLEYSAITLLSTLFLLYLTFS--TNKFKLDKKVGTACLVMYLV 518
            ||:.::...:||    |.::|.|| :.||.|| .|.||::.||  :.|::::|.:|....::|.|
Mouse  1053 WLLFSLINALQP----VPVSSNGL-FCAIVLL-FLMLLFVIFSIASCKWRMNKILGFTMFLLYFV 1111

  Fly   519 FMVFASLIE 527
            |:|.:.::|
Mouse  1112 FLVISVMLE 1120

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zyd	NP_001015261.3	ECM27	46..522	CDD:223604	183/700 (26%)
		Na_Ca_ex	48..192	CDD:279963	73/143 (51%)
		Na_Ca_ex	370..525	CDD:279963	64/156 (41%)
Slc24a1	NP_659062.1	2A1904	1..1130	CDD:273344	193/724 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820