Protein Alignment zyd and slc24a4b

DIOPT Version :9

• Sequence 1: NP_001015261.3
• Gene: zyd / 3354992
• FlyBaseID: FBgn0265767
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: XP_002665845.2
• Gene: slc24a4b / 100334346
• ZFINID: ZDB-GENE-081031-75
• Length: 636
• Species: Danio rerio
• Alignment Length: 558
• Identity: 236/558 - (42%)
• Similarity: 318/558 - (56%)
• Gaps: 92/558 - (16%)

  Fly    21 NCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNMSNDVA 85
            |||:|||.:||.|:|:.|:|:||||:||:||:||:|:|||:|||:|||.::||||..||:|.|||
Zfish   129 NCTEPAIHEFPDDVFTNAERKSGAVLLHIIAALYMFLALAIVCDDYFVTSLEKICEKLNLSEDVA 193

  Fly    86 GATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMTIPLDWWPLTR 150
            |||||||.:||||||.:|||.|||.||:||||||||||||||.:...|||.||..:.|.||.:.|
Zfish   194 GATFMAAGSSAPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVLLTWWAVFR 258

  Fly   151 DSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTFQKCAKGGVKQARSRSRSSN 215
            ||..|.::|..||..::||::.|:|:|:||.:||.|:.:|.|:...||
Zfish   259 DSFFYILSVVALIVFIYDEKIVWWESLVLVVMYACYILIMKFNSRLQK----------------- 306

  Fly   216 CSIHTKNSNEKEPELVENRICQNMANIQLNGGLNKEQAKATSTSGAGTTAI---SITTSTMT--- 274
              ..|:..|            :|:||.....|...|..|.:.....|:..:   .|..|...
Zfish   307 --FFTRKGN------------KNVANGNAAAGSELEDVKTSKIYSRGSVVMVDEIINASPPNYRF 357

  Fly   275 -----TTLSTTHSAGGGGGAVGLCSGPGAIVQMAP-LDDAEAESHVAVA-----AADEGRK--EE 326
                 ..:.|.|            .||...::||. |...|.:..|..|     |..:|:.  |.
Zfish   358 PEAGLRVMVTNH------------FGPKTRLRMASRLIITERQRLVQSANGVETAVVDGKPDIEN 410

  Fly   327 GYSLLSYPKDKS-----------------CFAQFTWLIIWPIHLLFRIAIPDCKKAKNNKIFPLT 374
            |    :.|:|||                 |..:..|||.||:.|:....||:|.|::..|.|.|:
Zfish   411 G----NVPEDKSTEEKESELTTPFRLPDGCMNRTKWLISWPLLLILFFTIPNCAKSRWEKYFMLS 471

  Fly   375 FIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICN 439
            ||:..|||...||.:.||:||||.||.|||.:|||||||||||||:.::|:|||::|.|.|.:.|
Zfish   472 FILSTVWIAVFSYFMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSN 536

  Fly   440 SIGSNTFDILLCLGVPWLIKAVFFPIQPGQNY---VAINSAGLEYSAITLLSTLFLLYLTFSTNK 501
            :||||.||||:.|||||.::.:      ..||   |.|||.||.||.:.||.::.|..|....|.
Zfish   537 TIGSNVFDILVGLGVPWALQTM------AVNYGSVVMINSRGLLYSVVLLLGSVALTILGIHLNH 595

  Fly   502 FKLDKKVGTACLVMYLVFMVFASLIELNVFFRVNLPTC 539
            :|||.|:|...|::|.||:.|:.:||.|||..||||.|
Zfish   596 WKLDFKLGVYVLLLYAVFLCFSIMIEYNVFTFVNLPMC 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zyd	NP_001015261.3	ECM27	46..522	CDD:223604	209/514 (41%)
		Na_Ca_ex	48..192	CDD:279963	86/143 (60%)
		Na_Ca_ex	370..525	CDD:279963	79/157 (50%)
slc24a4b	XP_002665845.2	TIGR00367	155..581	CDD:273039	195/478 (41%)
		Na_Ca_ex	156..298	CDD:279963	85/141 (60%)
		Na_Ca_ex	467..619	CDD:279963	79/157 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577432
Domainoid	1	1.000	187	1.000	Domainoid score	I3263
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	407	1.000	Inparanoid score	I1859
OMA	1	1.010	-	-		QHG50092
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	1	1.000	-	-		otm25347
orthoMCL	1	0.900	-	-		OOG6_103920
Panther	1	1.100	-	-	O	PTHR10846
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	1	1.000	-	-		X1463
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.840