Protein Alignment CG17167 and Slc24a3

DIOPT Version :10

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001343426.1
• Gene: Slc24a3 / 94249
• MGIID: 2137513
• Length: 645
• Species: Mus musculus
• Alignment Length: 600
• Identity: 170/600 - (28%)
• Similarity: 274/600 - (45%)
• Gaps: 141/600 - (23%)

  Fly    21 TVTQAKAATSNASSFLEVSLRYFDEQLLLDILPRAQCPGEDEGSPMDEFADLFTVDQLRQGWVVL 85
            |:|...|...::.:..|.:|..|         ||                |:|:.:..|||.|||
Mouse    72 TLTSEDAGLQSSKNCTEPALHEF---------PR----------------DIFSNEDRRQGAVVL 111

  Fly    86 HVFAAVYFFILLAIICNDYFLPTVECICEDLHLSKDVAAATFMATATSMPEFFTNTISTLILESD 150
            ||..|:|.|..|||:|:|:|:|::|.|||.||||:|||.|||||..:|.||.||:.|...|.:.|
Mouse   112 HVLCAMYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGD 176

  Fly   151 MGLGTIIGSLMFNTLGVAGLAALAIDKPVQLDWWPIARDCFIYVFNTIILLVLAWSGSISFTESC 215
            :|:|||:||.:||.|.:.|:..|...:.|.|..|.:.||...|..:.:.|:|..:...:|:.||.
Mouse   177 VGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVVALIVFIYDEKVSWWESL 241

  Fly   216 IMMGFLILYYLITFNNNKFMPAI--------------------RVFIEDRMNC------------ 248
            :    |:|.|||.....|:...|                    ...|:|..||
Mouse   242 V----LVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANF 302

  Fly   249 --------------------CFS---TRYDLTE--PP---------------------------E 261
                                .||   .|..:|.  ||                           |
Mouse   303 HRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGE 367

  Fly   262 NSAKAQLPLKKDPLSGDGLFV-----LNLPENTSSMSSTANLTRNKHLN------------DEDD 309
            :....::|:|....:|.|...     :|.......::.|.|.|.|::.:            ||||
Mouse   368 SEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDIVAETDNETENENEDNENNENDEEEEEDEDD 432

  Fly   310 VADVVPGSIYAYPRDASGWMQ-FWWIFVFPIKVTLSLLIPHPMK--YRRLYPLSFIMCILCIGGN 371
              |..|.:.:..|   ||.:: ..|.|.:|:...|...:|:..|  :.:.:.::|....|.|...
Mouse   433 --DEGPYTPFDPP---SGKLETVKWAFTWPLSFVLYFTVPNCNKPHWEKWFMVTFASSTLWIAAF 492

  Fly   372 AYLIVWMLTAFGVAIHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLGANSLAILL 436
            :|::|||:|..|..:.:|.::||:||||||:::|:.::|||..|.|...:.||||:|:|...||:
Mouse   493 SYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILI 557

  Fly   437 SLGVPWFIKN-CIHYGTGEPQQVGTQGIEYNILILIISTMALFIILSFSGYRLTKRVGVALFTVY 500
            .||:||.::. .:.||:  ..::.::|:.|::.:|:.|.......:..:.::|.|::|.....:|
Mouse   558 GLGLPWALQTLAVDYGS--YIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLFLY 620

  Fly   501 GVFIVLQILIEMNVF 515
            |||:...|:.|.|||
Mouse   621 GVFLCFSIMTEFNVF 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	2A1904	<53..>247	CDD:273344	77/213 (36%)
		ECM27	133..507	CDD:440296	121/478 (25%)
Slc24a3	NP_001343426.1	2A1904	<89..631	CDD:273344	162/577 (28%)
		Alpha-1	148..188		21/39 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	379..398		3/18 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	404..442		10/39 (26%)
		Alpha-2	520..551		14/30 (47%)