DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17167 and MHX

DIOPT Version :9

Sequence 1:	NP_001015257.2	Gene:	CG17167 / 3354991	FlyBaseID:	FBgn0039941	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_566105.1	Gene:	MHX / 819373	AraportID:	AT2G47600	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	115/545 - (21%)
Similarity:	205/545 - (37%)	Gaps:	114/545 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 ILPRAQC------PGEDEGSPMDEFADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYF---- 105
            :|...:|      |||:..|           |.||.   ||:.....|.||.|:.|...:|
plant    17 VLGHLRCENFFLFPGENTLS-----------DGLRG---VLYFLGLAYCFIGLSAITARFFKSME 67

  Fly   106 --------LPTVECI--CEDLHLSK----DVAAATFMATATSMPEFFTNTISTL-----ILESDM 151
                    :.|::.|  .|.:...|    .:|..:.:|..||.|:....||..:     .....:
plant    68 NVVKHSRKVVTIDPITKAEVITYKKVWNFTIADISLLAFGTSFPQISLATIDAIRNMGERYAGGL 132

  Fly   152 GLGTIIGSLMFNTLGVAGLAALA-----IDKPVQLDWW--PIARDCFIYVFNTIILLVLAWSGS- 208
            |.||::||..|:...:..:..:.     :.|...|..|  .:....:.|::..|||.|  ||.:
plant   133 GPGTLVGSAAFDLFPIHAVCVVVPKAGELKKISDLGVWLVELVWSFWAYIWLYIILEV--WSPNV 195

  Fly   209 ISFTESCIMMGFLILYYLITFNNNKFMPAIRVFIEDRMNCCFSTRYDLTEPPENSAKAQLPLKKD 273
            |:..|:.:.   ::.|.|:         .:..:.:|:.....|......:.||.....::...||
plant   196 ITLVEALLT---VLQYGLL---------LVHAYAQDKRWPYLSLPMSRGDRPEEWVPEEIDTSKD 248

  Fly   274 PLSGDGLFVLNLPENTSSMSSTANLTR--NKHLNDED------DVADVVPGSIYAYPRDASGWMQ 330
            ....|...|.:.....:..|.:.|:..  :.|..:.|      .|||..|.|.....:..:..:.
plant   249 DNDNDVHDVYSDAAQDAVESGSRNIVDIFSIHSANNDTGITYHTVADTPPDSATKKGKAKNSTVF 313

  Fly   331 FWWIFVFPIKVTLS---------------------LLIPHPMKYRRLYP-------LSFIMCILC 367
            ..|...|...:||.                     ||.|..:.:..:.|       ::||..:|.
plant   314 DIWKHQFVDAITLETSESKKVDSIYLRIAKSFWHLLLAPWKLLFAFVPPCNIAHGWIAFICSLLF 378

  Fly   368 IGGNAYLIVWMLTAFGVAIHVPTIVMGLTFLAAGSTMPEAVSSLISL-RNGENGIGVSNSLGANS 431
            |.|.|:::............:...|:..|.||:|::.|:.|:|.|:. |.......::|...:||
plant   379 ISGVAFVVTRFTDLISCVTGINPYVIAFTALASGTSWPDLVASKIAAERQLTADSAIANITCSNS 443

  Fly   432 LAILLSLGVPWFIKNCIHY-GTGEPQQV-GTQGIEYNILILIISTMALFIIL---------SFSG 485
            :.|.:.:||||.|....:| ...||..: ..:|:.:::||...:::...::|         ...|
plant   444 VNIYVGIGVPWLINTVYNYFAYREPLYIENAKGLSFSLLIFFATSVGCIVVLVLRRLIIGAELGG 508

  Fly   486 YRLTKRVGVALF-TVYGVFIVLQIL 509
            .||...:..|.| .::.||:||..|
plant   509 PRLWAWLTSAYFMMLWVVFVVLSSL 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	TIGR00367	85..503	CDD:273039	100/497 (20%)
		Na_Ca_ex	86..229	CDD:279963	37/173 (21%)
		Na_Ca_ex	356..509	CDD:279963	42/172 (24%)
MHX	NP_566105.1	caca	12..>221	CDD:273296	49/231 (21%)
MHX	NP_566105.1	caca	<316..539	CDD:273296	50/218 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910