Protein Alignment CG17167 and Slc24a2

DIOPT Version :9

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_006538405.1
• Gene: Slc24a2 / 76376
• MGIID: 1923626
• Length: 746
• Species: Mus musculus
• Alignment Length: 649
• Identity: 166/649 - (25%)
• Similarity: 269/649 - (41%)
• Gaps: 190/649 - (29%)

  Fly    50 DILPRAQCPGEDEGSPMDEFA------DLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPT 108
            |..|:.....||:.....|..      |:|::::.|:|.::|||...:|.||.|||:|:::|:|:
Mouse    97 DYTPQPPASQEDQAENSTEHTQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPS 161

  Fly   109 VECICEDLHLSKDVAAATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAAL 173
            :..|.|.|.:|.|||.|||||...|.||.||:.|...|..|::|:|||:||.:||.|.|.|:.||
Mouse   162 LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCAL 226

  Fly   174 AIDKPVQLDWWPIARDCFIYVFNTIILLVLAWSGSISFTESCIMMGFLILY-------------- 224
            ...:.:.|.|||:.||...|:.:.::|:.......|.:.||.:::.....|
Mouse   227 FSREILNLTWWPLFRDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAYVVFMKFNVQVERWV 291

  Fly   225 -YLITFNN-------------NKFMPAIRVFIEDRMNC------------CF-----STRY---- 254
             .:|:.||             ::|.||.:.  :.|..|            ||     :.|:
Mouse   292 KQMISRNNVIKVTVPEAQAKLSEFPPASQA--DGRTACPTITNDPDCQSLCFEVYPETARHGSCI 354

  Fly   255 ------DLTEPPENSAKAQLP---------------------------------LKK-------- 272
                  .|.|..:||...:.|                                 |::
Mouse   355 TNVNGEPLKEKTQNSCMEESPTAGDKDGPTLPVGSSSAACSCTSEECVAESKPRLQRGGSSASLH 419

  Fly   273 ----------------DPL----------------SGDGLF------------------------ 281
                            |||                :.:|.|
Mouse   420 NSLMRNSIFQLMIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHKIAKKKCQVDENERQN 484

  Fly   282 -------VLNLPENTSS------MSSTANLTRNKHLNDEDDVADVVPGSIYAYPRD----ASGW- 328
                   .:.||.:||:      .|..:...:|.:|:...:.||....:..|...|    :..|
Mouse   485 GAANHVEKIELPNSTSTEVEMTPSSEASEPVQNGNLSHNIEAADAPKATETAEEEDDQPLSLSWP 549

  Fly   329 ----MQFWWIFVFPIKVTLSLLIPHPMK--YRRLYPLSFIMCILCIGGNAYLIVWMLTAFGVAIH 387
                .|..::.||||...|.:.:|...|  .|:.:|::|...|..|...:||:||.....|..|.
Mouse   550 TNTRKQATFLIVFPIVFPLWITLPDVRKPASRKFFPITFFGSITWIAVFSYLMVWWAHQVGETIG 614

  Fly   388 VPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLGANSLAILLSLGVPWFIKNCIHYGT 452
            :...:||||.||||:::|:.::|:|..|.|...:.||:|:|:|...|.:.|.:||.:...||  .
Mouse   615 ISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTIIH--R 677

  Fly   453 GEPQQVGTQGIEYNILILIISTMALFIILSFS--GYRLTKRVGVALFTVYGVFIVLQILIEMNV 514
            ..|..|.:.|:...|::|.|  |.||:|||.:  .:|:.|.:|..:|.:|.||:|:.:|:|..|
Mouse   678 FSPVTVSSNGLFCAIVLLFI--MLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDKV 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	TIGR00367	85..503	CDD:273039	151/595 (25%)
		Na_Ca_ex	86..229	CDD:279963	57/157 (36%)
		Na_Ca_ex	356..509	CDD:279963	54/154 (35%)
Slc24a2	XP_006538405.1	2A1904	<99..746	CDD:273344	165/647 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820