Protein Alignment CG17167 and slc24a6a

DIOPT Version :9

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_009289475.1
• Gene: slc24a6a / 561209
• ZFINID: ZDB-GENE-100922-39
• Length: 639
• Species: Danio rerio
• Alignment Length: 647
• Identity: 175/647 - (27%)
• Similarity: 286/647 - (44%)
• Gaps: 162/647 - (25%)

  Fly     8 WRCLFFTLCGS-----------------FLTVTQAKAAT-----------SNASSFLEVSLRYFD 44
            |||  |..||.                 |:......|.|           |...|....:.|...
Zfish    10 WRC--FKRCGGGMKAVLTSRRQRLFYRLFICAVGLIAVTCFAQILHVTEHSKEESDQNWARRKLT 72

  Fly    45 EQLL----LDILPRAQCPGEDEGSPMDEF-ADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDY 104
            :|::    ....|||         .:.|| .|:||..|.|.|.::||||.|||.|..|||:|:.:
Zfish    73 QQIIEENQTSSTPRA---------AIHEFPQDIFTKGQRRHGAILLHVFCAVYMFYALAIVCDVF 128

  Fly   105 FLPTVECICEDLHLSKDVAAATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAG 169
            |:|::|.|||:||||:|||.|||||..:|.||.||:.|...|.:.|:|:|||:||.:||.|.:.|
Zfish   129 FVPSLEKICENLHLSEDVAGATFMAAGSSAPELFTSLIGVFITKGDLGVGTIVGSAVFNILVIIG 193

  Fly   170 LAALAIDKPVQLDWWPIARDCFIYVFNTIILLVLAWSGSISFTESCIMMGFLILYYLITFNNNKF 234
            :..:...:.:.|.|||:.||...|:.:.:.|:::.:...:.:.|:.|::....:|.||.    ||
Zfish   194 VCGIFAGQTITLTWWPLFRDSIFYILSVLALILIIYDEKVIWWETIILISMYGVYILIM----KF 254

  Fly   235 MPAIRVFIEDRMN-----CCFST-RYDLT--EPPENSAKAQLPLKKDPLSG---------DGLFV 282
            ...|..::|.|..     |..|: |.|::  |...:...:.:.|||...:|         |.|..
Zfish   255 NSQIWGWVEQRFGIPGQPCLVSSLRRDVSVGEASPHCDTSMILLKKGQNAGGQDSPVVMVDELMS 319

  Fly   283 LN-------------------LPENTSSMSSTANLTRNKHL------------------------ 304
            |:                   .|....||:....:|..:.|
Zfish   320 LHPHQFSFSEASLRVMITPHFSPRTRLSMAGRMLITERQRLIRNRSPGDSSGSGAGDTPGQDGPG 384

  Fly   305 ---------------------------------------------NDEDD--VADVVPGSIYAYP 322
                                                         :||:|  .||..|...:..|
Zfish   385 MEAVPWGLENGGALESETQPLEEPRRRSQGGELERVADIEDTQPKDDEEDEEEADEEPFRPFTVP 449

  Fly   323 RDASGWMQFWWIFVFPIKVTLSLLIPHPM--KYRRLYPLSFIMCILCIGGNAYLIVWMLTAFGVA 385
            .  ..|.|..|:|.:|:...|...:|:.:  ::.|.:.::|:...|.|...:||:|||:|.....
Zfish   450 E--GRWEQAKWMFSWPLSCLLYYTVPNCVLPRWERWFMVTFVASTLWIAVFSYLMVWMVTIISFT 512

  Fly   386 IHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLGANSLAILLSLGVPWFIKN-CIH 449
            :.:|.:|||:||||||:::|:.::|||..|.|...:.||||:|:|...|||.||.||.::. .:.
Zfish   513 LDIPDVVMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNIFDILLGLGFPWALRTLVVD 577

  Fly   450 YGTGEPQQVGTQGIEYNILILIISTMALFIILSFSGYRLTKRVGVALFTVYGVFIVLQILIE 511
            ||:  ...:.::|:.|::::|:.|.....:.:..:.:||.:|:|:.|..:|.:|::..|..|
Zfish   578 YGS--TVSINSKGLVYSVILLLASVFLTVLSVHLNHWRLDRRLGLGLMFLYAIFLLCSICFE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	TIGR00367	85..503	CDD:273039	148/527 (28%)
		Na_Ca_ex	86..229	CDD:279963	60/142 (42%)
		Na_Ca_ex	356..509	CDD:279963	51/153 (33%)
slc24a6a	XP_009289475.1	Na_Ca_ex	<85..637	CDD:332332	161/568 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577439
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10846
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850