DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17167 and slc8b1

DIOPT Version :9

Sequence 1:	NP_001015257.2	Gene:	CG17167 / 3354991	FlyBaseID:	FBgn0039941	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	XP_021333605.1	Gene:	slc8b1 / 560601	ZFINID:	ZDB-GENE-130530-900	Length:	301	Species:	Danio rerio

Alignment Length:	246	Identity:	68/246 - (27%)
Similarity:	104/246 - (42%)	Gaps:	47/246 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 DEG---SPMDEFADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVECICEDLHLSKDV 122
            |||   .|...|. |||...|... :.::|...::.|::|.:|.:|:|.|.:..|...|.|:.:|
Zfish    79 DEGFIKYPFVTFC-LFTPSLLPLA-ITIYVIWLLFLFLVLGLIASDFFCPNLSAIASTLRLTHNV 141

  Fly   123 AAATFMATATSMPEFFTNTISTLILES-----DMGLGTIIGSLMFNTLGVAGLAALAIDKPVQLD 182
            |..||:|.....|:.|    |.:...|     .:.:|.:.|:.:|.|..|||..||.  ||..:.
Zfish   142 AGVTFLALGNGAPDVF----SAMAAFSHPQTAGLAIGALFGAGIFVTTVVAGSVALV--KPFTVA 200

  Fly   183 WWPIARDCFIYVFNTIILLVLAWSGSISFTESCIMMGFLILYYLITFNNNKFMPAIRVFIEDRMN 247
            ..|..||...|:........:.:.|.||..||...:|..|.|.        |...:..:|.:|.
Zfish   201 SRPFLRDVIFYMAAVFWTFTVLYKGHISLGESVGYLGMYIAYV--------FTVILSSYIYNRQ- 256

  Fly   248 CCFSTRYDLTEPPENSAKAQLPLKKDPLSGD-------------GLFVLNL 285
                 ::.|||.|::|.:.|..:    ||.|             .||:|||
Zfish   257 -----KHQLTESPQSSDREQGGI----LSSDLTYRETVSIQAHGVLFLLNL 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	TIGR00367	85..503	CDD:273039	59/219 (27%)
		Na_Ca_ex	86..229	CDD:279963	42/147 (29%)
		Na_Ca_ex	356..509	CDD:279963
slc8b1	XP_021333605.1	Na_Ca_ex	66..>246	CDD:332332	52/182 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910