Protein Alignment CG17167 and slc24a1

DIOPT Version :10

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_009291877.3
• Gene: slc24a1 / 558299
• ZFINID: ZDB-GENE-060503-191
• Length: 741
• Species: Danio rerio
• Alignment Length: 645
• Identity: 170/645 - (26%)
• Similarity: 275/645 - (42%)
• Gaps: 164/645 - (25%)

  Fly    21 TVTQAKAATSNASSFLEVSLRYFDEQL------------LLDILPR--AQCPGEDEGSPMDEFAD 71
            |.|:|.:.|:|.:.   |...|.|..|            ...::|.  |..||:......:...|
Zfish    97 TTTEAPSTTTNRTI---VHCIYVDPDLPKPTPVPTPATETTTLVPNTTASQPGDAPHMKGEYPED 158

  Fly    72 LFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVECICEDLHLSKDVAAATFMATATSMPE 136
            :|:::..|:|||.||:|..||.|:.|||:|:::|:||:..|.:.|.:|.|||.|||||...|.||
Zfish   159 IFSIEDRRKGWVSLHIFGMVYMFVSLAIVCDEFFVPTLGVITDKLAISDDVAGATFMAAGGSAPE 223

  Fly   137 FFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAALAIDKPVQLDWWPIARDCFIYVFNTIILL 201
            .||:.|...|..|::|:|||:||.:||.|.|.|:.||...:.:.|.|||:.||...|:.:.|:|:
Zfish   224 LFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGMCALFSREMLHLTWWPLFRDVSFYILDLIMLI 288

  Fly   202 VLAWSGSISFTESCIMMGFLILYYLITFNN-------------NKFMPAIRVFIEDRMNCCFSTR 253
            :.....:|.:.||.:::|...||  :||..             :|....::|...:.......|.
Zfish   289 IFFLDNTIMWWESMMLVGGYALY--VTFMKFNVQLERAFKSQLSKHKSIVKVIAVEEPEKDNGTS 351

  Fly   254 YDLTEPPENSAKAQLPLKK----------------------------DPLSGDGLF--------- 281
            .:...|||...|.:|.||.                            |||..:.:|
Zfish   352 GEENRPPEPEDKNRLKLKPTLQRGGSSASLHNSTMRNTIFQLMIHTLDPLGEESVFNGDAKARSS 416

  Fly   282 ------------VLN-----LPENTSSMSSTANLTRNKHLNDEDDV------------------A 311
                        :||     ..||.....|.....:::...|..|.                  .
Zfish   417 LECKVKFKDKAQILNDMARGKVENKKKEKSGEGDDQSEQTKDSKDAPPGAKDEDTNQKSEAQKDG 481

  Fly   312 DVVPGSIYAYP--RDASG-------------------------------------------W--- 328
            |:..|.....|  .|.||                                           |
Zfish   482 DIAAGGGSENPGGSDNSGDDDEDDSDEESDDDDDDDDDDDDDDDENEDEAGEDGDEPLSLEWPDT 546

  Fly   329 --MQFWWIFVFPIKVTLSLLIP---HPMKYRRLYPLSFIMCILCIGGNAYLIVWMLTAFGVAIHV 388
              .|..::|:.||...|.|.:|   :|.. ::.:.::|:..|:.|...:||:||.....|..|.:
Zfish   547 RRKQATYLFLLPIVFPLWLTVPDVRNPAS-KKFFVITFLGSIVWIAIFSYLMVWWAHQVGETIGI 610

  Fly   389 PTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLGANSLAILLSLGVPWFIKNCIHYGTG 453
            ...:||||.||||:::|:.::|:|..|.|...:.||:|:|:|...|.:.|.|||.:.:..|  :.
Zfish   611 SEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITMGLPVPWLMFSFFH--SF 673

  Fly   454 EPQQVGTQGIEYNILILIISTMALFIILSFSG--YRLTKRVGVALFTVYGVFIVLQILIE 511
            .|..|.:.|:...|::|.:  |.||:|:|.:.  :|:.|.:|..:|.:|.||:||.:::|
Zfish   674 APVPVSSNGLFCAIVLLFL--MLLFVIISIAACKWRMNKVLGFTMFILYFVFLVLSVMLE 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	2A1904	<53..>247	CDD:273344	74/208 (36%)
		ECM27	133..507	CDD:440296	125/513 (24%)
slc24a1	XP_009291877.3	None