Protein Alignment CG17167 and slc24a3

DIOPT Version :9

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_685302.4
• Gene: slc24a3 / 557196
• ZFINID: ZDB-GENE-090312-67
• Length: 660
• Species: Danio rerio
• Alignment Length: 587
• Identity: 164/587 - (27%)
• Similarity: 270/587 - (45%)
• Gaps: 128/587 - (21%)

  Fly    37 EVSLRYFDEQLLLDILPRA--QC--PGEDEGSPMDEFA-DLFTVDQLRQGWVVLHVFAAVYFFIL 96
            ::...|.||   :.:.|.|  .|  ||      :.||. |:||..:..:|.|.|||..|:|.|..
Zfish    83 DIDSNYTDE---VQLGPNADKNCTPPG------IHEFPDDIFTQQERLEGAVALHVLCAMYMFYA 138

  Fly    97 LAIICNDYFLPTVECICEDLHLSKDVAAATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLM 161
            ||::|:|||:|::|.|||.||||:|||.|||||..:|.||.||:.|...|.:.|:|:|||:||.:
Zfish   139 LALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAV 203

  Fly   162 FNTLGVAGLAALAIDKPVQLDWWPIARDCFIYVFNTIILLVLAWSGSISFTESCIMMGFLILYYL 226
            ||.|.:.|:..:...:.|:|..|.:.||...|......|:|..:...:::.||.|::...::|.|
Zfish   204 FNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVTWWESLILIVLYLVYIL 268

  Fly   227 ITFNNNKFMPAIRVFIEDR---------------------------------------------- 245
            |.    ||...:..|||.|
Zfish   269 IM----KFNSRVVHFIERRKKNPANLGNGTASNTDIDDGCDATVVLLKKANFHRKPSVLMVDELL 329

  Fly   246 -----------------MNCCFSTRYDLTEPPENSAKAQLPLKKDPL------SGDGLFVLNLP- 286
                             :...||.|..||     .|...|..::..|      :||....:.:|
Zfish   330 SAYPHQLTFSEAGMRIMITSHFSPRTRLT-----MASRMLITERQRLINSRFSNGDSEVTVKMPG 389

  Fly   287 ----EN-----------------------TSSMSSTANL---TRNKHLNDEDDVADVVPGSIYAY 321
                ||                       ..:.:.|.|.   ..|...::|::..|...|....:
Zfish   390 KRGVENGLAGPDRGLNGRKGGHHDDDRGGAEAGTDTENENEDNENNENDEEEEEEDENEGPYVPF 454

  Fly   322 PRDASGWMQFWWIFVFPIKVTLSLLIPHPM--KYRRLYPLSFIMCILCIGGNAYLIVWMLTAFGV 384
            .....|..:..|:..:|:.:.|...:|:..  ::.|.|.:|||...:.|...:|::|||:|..|.
Zfish   455 RCPGGGINKLKWLLAWPLSMLLFFTVPNSANPRWERWYMVSFISSTIWIAFFSYIMVWMVTVIGY 519

  Fly   385 AIHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLGANSLAILLSLGVPWFIKN-CI 448
            .:.:|.::||:||||||:::|:.::|||..|.|...:.:|||:|:|...||:.||:||.::. .|
Zfish   520 TMGIPDVIMGITFLAAGTSVPDCLASLIVARQGMGDMAISNSIGSNVFDILIGLGLPWALQTLAI 584

  Fly   449 HYGTGEPQQVGTQGIEYNILILIISTMALFIILSFSGYRLTKRVGVALFTVYGVFIVLQILIEMN 513
            :||:  ...:.::|:.:::.:|:.|.....:.:..:.::|.||:|.|...:|.||:...||||.|
Zfish   585 NYGS--TIHLNSKGLIFSVGLLLASVFLTVLGVHLNNWKLDKRLGFACLLMYAVFLCFSILIEFN 647

  Fly   514 VF 515
            :|
Zfish   648 IF 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	TIGR00367	85..503	CDD:273039	141/520 (27%)
		Na_Ca_ex	86..229	CDD:279963	60/142 (42%)
		Na_Ca_ex	356..509	CDD:279963	51/153 (33%)
slc24a3	XP_685302.4	TIGR00367	127..637	CDD:273039	141/520 (27%)
		Na_Ca_ex	128..270	CDD:279963	59/141 (42%)
		Na_Ca_ex	491..643	CDD:279963	51/153 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577442
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10846
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850