Protein Alignment CG17167 and Slc24a4

DIOPT Version :10

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_742164.2
• Gene: Slc24a4 / 238384
• MGIID: 2447362
• Length: 622
• Species: Mus musculus
• Alignment Length: 568
• Identity: 163/568 - (28%)
• Similarity: 281/568 - (49%)
• Gaps: 106/568 - (18%)

  Fly    45 EQLLLDILPRAQCPGEDEGSPM---------DEF-ADLFTVDQLRQGWVVLHVFAAVYFFILLAI 99
            :.:|||.....:......|:|:         .|| .|||:..:.:.|.|:||:..|:|.|..|||
Mouse    52 KHVLLDTWRNRKLMAPINGTPLAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAI 116

  Fly   100 ICNDYFLPTVECICEDLHLSKDVAAATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLMFNT 164
            :|:|:|:|::|.|||.||||:|||.|||||..:|.||.|.:.|...|...|:|:|||:||.:||.
Mouse   117 VCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNI 181

  Fly   165 LGVAGLAALAIDKPVQLDWWPIARDCFIYVFNTIILLVLAWSGSISFTESCIMMGFLILYYLITF 229
            |.:.|:..|...:.|:|.||.:.||...|..:.|:|:...:...|.:.|..:::...:.|.||..
Mouse   182 LCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYVFYILIMK 246

  Fly   230 NNNKFMPAIRVF-----------------IEDRMNCCFSTRYDLTEPPENSAKAQLPLKKDPL-- 275
            .|.|    ::.|                 :||..:....:..|.:.|.....|.:.|..|.|:
Mouse   247 YNMK----MQTFFTTKQKSIANGNPVSNELEDGNDLYDGSYDDPSVPLLGQVKEKPPYGKTPVVM 307

  Fly   276 ----------------SGDGLFVLNL--PENTSSMSS------------TANLTRNKHL------ 304
                            :|..:.:.|.  |.....|:|            :||...:|.|
Mouse   308 VDEILSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVNSKPLQNGRHE 372

  Fly   305 ----------NDED------------------DVADVVPGSIYAYPRDASGWMQFWWIFVFPIKV 341
                      |.||                  :..:.|..|.::.| :|.| .:..|:|.:|:..
Mouse   373 NMENGNVPVENPEDPQQGQEQQPPPQPPPPEPESVETVFLSPFSMP-EAKG-DKAKWVFTWPLIF 435

  Fly   342 TLSLLIPHPMK--YRRLYPLSFIMCILCIGGNAYLIVWMLTAFGVAIHVPTIVMGLTFLAAGSTM 404
            .|.:.||:..|  :.:.:.::||...|.|...:||:||::|..|..:.:|.::||:||||||:::
Mouse   436 LLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSV 500

  Fly   405 PEAVSSLISLRNGENGIGVSNSLGANSLAILLSLGVPWFIKN-CIHYGTGEPQQVGTQGIEYNIL 468
            |:.::|||..|.|...:.|||::|:|...||:.||:||.::. .|:||:  ..::.::|:.|::
Mouse   501 PDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGS--TVKINSRGLVYSV- 562

  Fly   469 ILIISTMALFII-LSFSGYRLTKRVGVALFTVYGVFIVLQILIEMNVF 515
            :|::.::||.:: :..:.:||.:::|:.:..:|.||:...|:||.|||
Mouse   563 VLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVF 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	2A1904	<53..>247	CDD:273344	74/220 (34%)
		ECM27	133..507	CDD:440296	117/460 (25%)
Slc24a4	NP_742164.2	2A1904	<80..606	CDD:273344	153/534 (29%)
		Alpha-1	139..179		20/39 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	358..408		7/49 (14%)
		Alpha-2	495..526		13/30 (43%)