Protein Alignment CG17167 and Slc24a1

DIOPT Version :9

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_659062.1
• Gene: Slc24a1 / 214111
• MGIID: 2384871
• Length: 1130
• Species: Mus musculus
• Alignment Length: 745
• Identity: 165/745 - (22%)
• Similarity: 268/745 - (35%)
• Gaps: 301/745 - (40%)

  Fly    53 PRAQCPGEDEGSPMDEF-ADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVECICEDL 116
            |.|..||.....|..|: .|||:|:..||||||||:|..:|.|:.|||:|::||:|.:..|...|
Mouse   391 PSALPPGWPNLHPKAEYPPDLFSVEDRRQGWVVLHIFGMMYVFVALAIVCDEYFVPALGVITHKL 455

  Fly   117 HLSKDVAAATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAALAIDKPVQL 181
            .:|:|||.|||||...|.||.||:.|...|..|::|:|||:||.:||.|.|.|..||...:.:.|
Mouse   456 QISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNL 520

  Fly   182 DWWPIARDCFIYVFNTIILLVLAWSGSISFTESCIMMGFLILY--YLITFNNNKFMPAIRVFIED 244
            .|||:.||...|:.:..:|:|......|::.||.::   |:.|  |:.|...||   .|.:::::
Mouse   521 TWWPLFRDVSFYILDLSMLIVFFLDSFIAWWESLLL---LLAYALYVFTMKWNK---QIELWVKE 579

  Fly   245 RMNCCFSTR--------YDLTEPPE---------NSAKAQLPL---------------------- 270
            ::    |.|        .||::|.|         :|.|.:||.
Mouse   580 QL----SRRPVAKVMALGDLSKPSEDAVEENEQQDSKKLKLPSVLTRGSSSASLHNSIIRNTIYH 640

  Fly   271 ----KKDPLSGDGLFVLNLPENTSSMSSTANLTRNKHLNDEDDVADVVPGSIYAYPR-DASG--- 327
                ..||| |:.....:..|:.:..:...:.|:.:...|||:.|::...::...|. ||.|
Mouse   641 LMLHSLDPL-GEARPSKDKQESLNQEARVLSQTKAESSPDEDEPAELPAVTVTPAPAPDAKGDQE 704

  Fly   328 ----------------------------------------------------------------- 327
                                                                             
Mouse   705 DDPGCQEDVDEAERRGEMTGEEGEKETETEGKKDEQEGETEAERKEDEQEEETEAEGKEQEGETE 769

  Fly   328 ----------------------------------------------------------------- 327
                                                                             
Mouse   770 AEGKEDEQEGETEAEGKKDEQEGETEAEGKEEQEGETEAEGKEDEQEGETEAEGKEEQEGETEAE 834

  Fly   328 ----------------------------------------------------------------- 327
                                                                             
Mouse   835 SKEVEQERETEAEGKDKHEGQGETQPDDTEVKDGEGETEANAEDQCEATQGEKGADGGGESDGGD 899

  Fly   328 --------------------------------W-----MQFWWIFVFPIKVTLSLLIP--HPMKY 353
                                            |     .|..::|:.||...|.|.||  ...:.
Mouse   900 SEEEEDEEDEEEEEEEDEEEEEEENEEPLSLEWPDSRQKQAIYLFLLPIVFPLWLTIPDVRRQES 964

  Fly   354 RRLYPLSFIMCILCIGGNAYLIVWMLTAFGVAIHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGE 418
            |:.:.::|:..|:.|...:||:||.....|..|.:...:||||.||||:::|:.::|:|..|.|.
Mouse   965 RKFFVITFLGSIIWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGL 1029

  Fly   419 NGIGVSNSLGANSLAILLSLGVPWFIKNCIHYGTGEPQQVGTQGIEYNILILIISTMALFIILSF 483
            ..:.||:|:|:|...|.:.|.|||.:.:.|:  ..:|..|.:.|:...|::|.:  |.||:|.|.
Mouse  1030 GDMAVSSSVGSNIFDITVGLPVPWLLFSLIN--ALQPVPVSSNGLFCAIVLLFL--MLLFVIFSI 1090

  Fly   484 SG--YRLTKRVGVALFTVYGVFIVLQILIE 511
            :.  :|:.|.:|..:|.:|.||:|:.:::|
Mouse  1091 ASCKWRMNKILGFTMFLLYFVFLVISVMLE 1120

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	TIGR00367	85..503	CDD:273039	145/702 (21%)
		Na_Ca_ex	86..229	CDD:279963	58/144 (40%)
		Na_Ca_ex	356..509	CDD:279963	51/154 (33%)
Slc24a1	NP_659062.1	2A1904	1..1130	CDD:273344	165/745 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820