Protein Alignment CG17167 and ncx-5

DIOPT Version :9

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_505690.2
• Gene: ncx-5 / 191715
• WormBaseID: WBGene00003570
• Length: 656
• Species: Caenorhabditis elegans
• Alignment Length: 607
• Identity: 151/607 - (24%)
• Similarity: 255/607 - (42%)
• Gaps: 147/607 - (24%)

  Fly    37 EVSLRY-------FDEQLLLDILPRAQCPGEDEGSPMDEFADLFTVDQLRQGWVVLHVFAAVYFF 94
            |:|.|:       ||     |..||.|.......|...  ||:|::...|:|.|::|:...:|.|
 Worm    53 EISKRHRRSVEYEFD-----DCRPRIQTTSNANSSQFP--ADIFSLQTRRRGGVIVHIGLLIYMF 110

  Fly    95 ILLAIICNDYFLPTVECICEDLHLSKDVAAATFMATATSMPEFFTNTISTLILESDMGLGTIIGS 159
            :.||::|:::|:|::..|.|.|.:|.|||.|||||...|.|||||:.....:.:.::|:|||:||
 Worm   111 VALAVVCDEFFVPSLSVITEVLAISDDVAGATFMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGS 175

  Fly   160 LMFNTLGVAGLAALAIDKPVQLDWWPIARDCFIYVFNTIILLVLAWSGSISFTESCIMMGFLILY 224
            ..||.|.|.....|...:.:.|.|||:.||...|..:..:||:......|.:.|:.:|....|.|
 Worm   176 ATFNILCVLAFCTLFSRQVLHLTWWPLFRDMSFYTLSLFLLLIFFGDEVIEWQEALVMFSMYIAY 240

  Fly   225 -YLITFN------NNKFM---------PAIRVFIEDRMNCCFSTRYDLTEPPENSAKAQLPLKKD 273
             :.:.||      ..:|:         .|....::....|        |....:|..||.|.:..
 Worm   241 GFFMKFNGFLELKTKQFLFRKVGIGSEIAPETIVDAAAGC--------TPRSPHSLGAQGPRRSF 297

  Fly   274 PLSGDG--------LFVLNLPENTSSMSSTANLTRNKHL-------------------------- 304
            |:...|        ..|:...::|||.||:::..|:..:
 Worm   298 PMIHGGQEVRKSIAQLVIGDEDDTSSSSSSSSSERSNKIKPVSNGVPEIRQNGRTIMVKPANDPD 362

  Fly   305 ---NDEDDVADVVP------------------------GSIYAYPRDA----SGWMQF------- 331
               |:::.:..|:.                        ...|..|.:|    :|.::.
 Worm   363 AKFNNQNSIKTVITPIDFGDDHTIVINNNNNGKRKNGNNGTYLTPVEAINPSNGHLELAQTNGNP 427

  Fly   332 -----------------------W---------WIFVFPIKVTLSLLIPHPMK--YRRLYPLSFI 362
                                   |         ::|:.||...|:..:|...|  .|:.:.::||
 Worm   428 VPPIALDNLSIASSTAEKPLDLSWPEANHKKLIYLFLAPITFPLAYTLPDVRKPSLRKFFAITFI 492

  Fly   363 MCILCIGGNAYLIVWMLTAFGVAIHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSL 427
            ..||.|...:||:||.....|....:||.:||||.||||:::|:.::|:|..|.|...:.||:|:
 Worm   493 GAILWIAAYSYLMVWWANTIGETFGIPTEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSI 557

  Fly   428 GANSLAILLSLGVPWFIKNCIHYGTGEPQQ---VGTQGIEYNILILIISTMALFIILSFSGYRLT 489
            |:|...:.:.|.:||.|...|.....||.|   |.:.|:..::.:|....:.|...::.|.:::.
 Worm   558 GSNLFDVCVGLPIPWLIHFAIGVFKSEPTQNISVTSNGLVCSLGLLFAMLIVLLTCVAISRWKMD 622

  Fly   490 KRVGVALFTVYGVFIVLQILIE 511
            |..|:.:...|..|.:|.||:|
 Worm   623 KFFGLLMIFSYCGFCMLCILLE 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	TIGR00367	85..503	CDD:273039	130/542 (24%)
		Na_Ca_ex	86..229	CDD:279963	51/143 (36%)
		Na_Ca_ex	356..509	CDD:279963	48/155 (31%)
ncx-5	NP_505690.2	Na_Ca_ex	102..244	CDD:279963	51/141 (36%)
		Na_Ca_ex	486..642	CDD:279963	48/155 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820