Protein Alignment CG17167 and ncx-4

DIOPT Version :10

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001040663.1
• Gene: ncx-4 / 172834
• WormBaseID: WBGene00003569
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 150/520 - (28%)
• Similarity: 249/520 - (47%)
• Gaps: 57/520 - (10%)

  Fly    48 LLDILPRAQCPGEDEGSPMDEF-ADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVEC 111
            ||....|:..|...:.:...:| .|.|:::|.:.|:||||:...:|.|:.|||:|:::|:|:::.
 Worm    66 LLPTCNRSLAPPAPDVNDDGQFPPDPFSLEQRQNGFVVLHMCGLIYMFVSLAIVCDEFFVPSLDV 130

  Fly   112 ICEDLHLSKDVAAATFMATATSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAALAID 176
            :.|.|.||.|||.|||||...|.|||||:.|...|.::::|:|||:||..||.|.|.....|...
 Worm   131 LTEKLSLSDDVAGATFMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVLAFCTLFSK 195

  Fly   177 KPVQLDWWPIARDCFIYVFNTIILLVLAWSGSISFTESCIMMGFLILYYLITFNNNKFMPAIRVF 241
            ..:.|.|||:.||..||:....:|:.......|:|.|:..|....|:|..:...|.:....::..
 Worm   196 SILDLTWWPLFRDVSIYMLALAMLVFFFMDEMITFPEALAMFSIYIVYCTVMKFNGQLEQLVKKG 260

  Fly   242 IEDRMNCCFSTRYDLTEPPEN------------------SAKAQ-LP-LKKDPLSGDGLFVL--- 283
            .:........|:....:.|.|                  ||:.| :| |....:..:|:..|
 Worm   261 SDSEEASAHETQKLAADVPHNNNNNDLAQLEGSELRRRSSARRQSVPILHSGTMFRNGIMQLMNQ 325

  Fly   284 ---NLPENT---SSMSSTANLTRNKH----LNDEDDVADVVPGSIYAY----------PRDASGW 328
               .|||::   .|..|.:|:....|    ||....:.|.....|...          |.|.: |
 Worm   326 TLEQLPEDSEEDDSSRSRSNVNIESHDMHRLNVNQSMPDRRSSQIEEIKSLLEEQEEKPLDMT-W 389

  Fly   329 MQFW-----WIFVFPIKVTLSLLIPHPMK--YRRLYPLSFIMCILCIGGNAYLIVWMLTAFGVAI 386
            .:.|     ::.:.|:.:.:.:.||...|  .|.|||.:||:.||.|...:||:||.....|...
 Worm   390 PETWVKRLTYVLLAPVVIPMWVTIPDVRKSHNRGLYPATFIISILWIAFFSYLMVWWANTIGETF 454

  Fly   387 HVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLGANSLAILLSLGVPWFIKNCIHY- 450
            .:||.::|||.||||:::|:.::|:|..|.|...:.||:|:|:|...:.:.|.:||.:...|.|
 Worm   455 VIPTEIIGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDVCVGLPIPWLLYFLIEYI 519

  Fly   451 -GTGEPQ---QVGTQGIEYNILILIISTMALFIILSFSGYRLTKRVGVALFTVYGVFIVLQILIE 511
             ...||.   .|.::|:..::.:|.|..:.|...:..||:::.|..|:.:...|..|.|..:.:|
 Worm   520 KHPNEPLSPISVSSKGLLCSVGMLFIMLIVLVFAIFLSGWKMNKIFGILMIVSYVFFCVFSVSLE 584

  Fly   512  511
             Worm   585  584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	2A1904	<53..>247	CDD:273344	66/194 (34%)
		ECM27	133..507	CDD:440296	116/428 (27%)
ncx-4	NP_001040663.1	2A1904	<48..594	CDD:273344	150/520 (29%)