Protein Alignment CG17167 and SLC24A4

DIOPT Version :9

• Sequence 1: NP_001015257.2
• Gene: CG17167 / 3354991
• FlyBaseID: FBgn0039941
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_011534738.1
• Gene: SLC24A4 / 123041
• HGNCID: 10978
• Length: 669
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 156/544 - (28%)
• Similarity: 271/544 - (49%)
• Gaps: 113/544 - (20%)

  Fly    68 EF-ADLFTVDQLRQGWVVLHVFAAVYFFILLAIICNDYFLPTVECICEDLHLSKDVAAATFMATA 131
            || .|||:..:.:.|.|:||:..|:|.|..|||:|:|:|:|::|.|||.||||:|||.|||||..
Human   131 EFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAG 195

  Fly   132 TSMPEFFTNTISTLILESDMGLGTIIGSLMFNTLGVAGLAALAIDKPVQLDWWPIARDCFIYVFN 196
            :|.||.|.:.|...|...|:|:|||:||.:||.|.:.|:..|...:.|:|.||.:.||...|..:
Human   196 SSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTIS 260

  Fly   197 TIILLVLAWSGSISFTESCIMMGFLILYYLITFNNNKFMPAIRVFIEDRM-------------NC 248
            .|:|:|..:...|.:.|..::: .|.::|::....|..|.|.....:..:             |.
Human   261 VIVLIVFIYDEQIVWWEGLVLI-ILYVFYILIMKYNVKMQAFFTVKQKSIANGNPVNSELEAGND 324

  Fly   249 CFSTRYDLTEPPENSAKAQLPL----KKDPLSGDGLFVL------------NLPE---------- 287
            .:...||  :|       .:||    |:.|..|....|:            ..||
Human   325 FYDGSYD--DP-------SVPLLGQVKEKPQYGKNPVVMVDEIMSSSPPKFTFPEAGLRIMITNK 380

  Fly   288 ----------------------NTSSMSSTANLTRNKHLNDEDD--------------------- 309
                                  |:::..|:..|...:|.|.|:.
Human   381 FGPRTRLRMASRIIINERQRLINSANGVSSKPLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQ 445

  Fly   310 ---------VADVVPGSIYAYPRDASGWMQFWWIFVFPIKVTLSLLIPHPMK--YRRLYPLSFIM 363
                     .||.:  |.::.| :|.| .:..|:|.:|:...|.:.||:..|  :.:.:.::||.
Human   446 PPPPEPEPVEADFL--SPFSVP-EARG-DKVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFIT 506

  Fly   364 CILCIGGNAYLIVWMLTAFGVAIHVPTIVMGLTFLAAGSTMPEAVSSLISLRNGENGIGVSNSLG 428
            ..|.|...:|::||::|..|..:.:|.::||:||||||:::|:.::|||..|.|...:.|||::|
Human   507 ATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIG 571

  Fly   429 ANSLAILLSLGVPWFIKN-CIHYGTGEPQQVGTQGIEYNILILIISTMALFII-LSFSGYRLTKR 491
            :|...||:.|||||.::. .::||:  ..::.::|:.|:: :|::.::||.:: :..:.:||.::
Human   572 SNVFDILVGLGVPWGLQTMVVNYGS--TVKINSRGLVYSV-VLLLGSVALTVLGIHLNKWRLDRK 633

  Fly   492 VGVALFTVYGVFIVLQILIEMNVF 515
            :||.:..:|.:|:...|:||.|||
Human   634 LGVYVLVLYAIFLCFSIMIEFNVF 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17167	NP_001015257.2	TIGR00367	85..503	CDD:273039	142/512 (28%)
		Na_Ca_ex	86..229	CDD:279963	59/142 (42%)
		Na_Ca_ex	356..509	CDD:279963	49/154 (32%)
SLC24A4	XP_011534738.1	TIGR00367	149..645	CDD:273039	142/512 (28%)
		Na_Ca_ex	150..292	CDD:279963	59/142 (42%)
		Na_Ca_ex	499..651	CDD:279963	49/154 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10846
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850