Protein Alignment CG12061 and Slc24a3

DIOPT Version :9

• Sequence 1: NP_001104467.2
• Gene: CG12061 / 3354990
• FlyBaseID: FBgn0040031
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_445957.2
• Gene: Slc24a3 / 85267
• RGDID: 69256
• Length: 642
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 174/548 - (31%)
• Similarity: 261/548 - (47%)
• Gaps: 155/548 - (28%)

  Fly    34 ARNCTLPAIVEFP-----NLMRQKSWIAIVVSTLVSMYLFVILAIVCDDYLVPAMERLCYTLRMT 93
            ::|||.||:.|||     |..|::.  |:|:..|.:||:|..|||||||:.||::|::|..|.::
  Rat    83 SKNCTEPALHEFPRDIFSNEDRRQG--AVVLHVLCAMYMFYALAIVCDDFFVPSLEKICERLHLS 145

  Fly    94 YDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFT-QPTKLDWW 157
            .|||||||:||.:||||||.:.:|.|:|.||:|:||||||:|||||.|.||||:|. |...|..|
  Rat   146 EDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSW 210

  Fly   158 PVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYISYVIQLS--------FDRRIQ---NLV 211
            .:.||:.:|.:::.:|...::|..|.|:|:..|:|:|:.|:|.:.        |:||.:   |:|
  Rat   211 CLLRDSIYYTLSVVALIVFIYDEKVSWWESLVLVLMYLIYIIIMKYNACIHQCFERRTKGAGNMV 275

  Fly   212 R--------------------------HEHAESELLDE------------------------DPM 226
            .                          |..|...::||                        .|.
  Rat   276 NGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPK 340

  Fly   227 TR------------------------EEE--------------------PLKGF----RDHVCAK 243
            ||                        |.|                    |.:|.    ||.:.|:
  Rat   341 TRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDIVAE 405

  Fly   244 ---------------------------PKTEYN----FYQWTWWAIKYPAELMLACTVPSA---- 273
                                       |.|.::    ..:...||..:|...:|..|||:.
  Rat   406 ADNETENENEDENNENDEEEDEDDDEGPYTPFDPPSGKLETVKWAFTWPLSFVLYFTVPNCNKPH 470

  Fly   274 -RSIFFLSMISAILWISLISYLLTWFLTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKG 337
             ...|.::..|:.|||:..||::.|.:||:||.|.|||.|||:|.||||||||:..:|.||:::|
  Rat   471 WEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG 535

  Fly   338 YGSMAICNAIGSNTFDILVCLGLPWLLKILI--YQQKIDIDSTALTITTAMLVVTAAVLYLGLLA 400
            .|.||:.|:||||.||||:.|||||.|:.|.  |...|.::|..|..:..:|:.:..|...|:..
  Rat   536 MGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHL 600

  Fly   401 RRFVMGKTVGYLSIIFYALFLIIACTLE 428
            .::.:.|.:|...:..|.:||..:...|
  Rat   601 NKWQLDKKLGCGCLFLYGVFLCFSIMTE 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12061	NP_001104467.2	TIGR00367	61..422	CDD:273039	160/508 (31%)
		Na_Ca_ex	62..199	CDD:279963	69/137 (50%)
		Na_Ca_ex	276..424	CDD:279963	63/149 (42%)
Slc24a3	NP_445957.2	TIGR00367	111..604	CDD:273039	156/492 (32%)
		Na_Ca_ex	112..254	CDD:279963	70/141 (50%)
		Na_Ca_ex	474..626	CDD:279963	63/151 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338072
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10846
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950